Towards the identification of the loci of adaptive evolution.
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Authors
Pardo-Diaz, Carolina
Salazar, Camilo
Jiggins, Chris D
Abstract
- Establishing the genetic and molecular basis underlying adaptive traits is one of the major goals of evolutionary geneticists in order to understand the connection between genotype and phenotype and elucidate the mechanisms of evolutionary change. Despite considerable effort to address this question, there remain relatively few systems in which the genes shaping adaptations have been identified. 2. Here, we review the experimental tools that have been applied to document the molecular basis underlying evolution in several natural systems, in order to highlight their benefits, limitations and suitability. In most cases, a combination of DNA, RNA and functional methodologies with field experiments will be needed to uncover the genes and mechanisms shaping adaptation in nature.
Description
Keywords
DNA mapping, QTL, adaptation, candidate genes, expression, functional analysis, resequencing
Journal Title
Methods Ecol Evol
Conference Name
Journal ISSN
2041-210X
2041-210X
2041-210X
Volume Title
6
Publisher
British Ecological Society
Publisher DOI
Sponsorship
Biotechnology and Biological Sciences Research Council (BB/K019945/1)
Biotechnology and Biological Sciences Research Council (BB/H01439X/1)
Biotechnology and Biological Sciences Research Council (BB/H01439X/1)
This work was supported by BBSRC grant number BB/K019945/1 to CJ.