Nondeterministic self-assembly with asymmetric interactions.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Tesoro, Salvatore https://orcid.org/0000-0003-4011-366X
Göpfrich, K
Kartanas, T
Keyser, UF
Ahnert, SE
Abstract
We investigate general properties of nondeterministic self-assembly with asymmetric interactions, using a computational model and DNA tile assembly experiments. By contrasting symmetric and asymmetric interactions we show that the latter can lead to self-limiting cluster growth. Furthermore, by adjusting the relative abundance of self-assembly particles in a two-particle mixture, we are able to tune the final sizes of these clusters. We show that this is a fundamental property of asymmetric interactions, which has potential applications in bioengineering, and provides insights into the study of diseases caused by protein aggregation.
Description
Keywords
cond-mat.soft, cond-mat.soft, cond-mat.stat-mech
Journal Title
Phys Rev E
Conference Name
Journal ISSN
2470-0045
2470-0053
2470-0053
Volume Title
94
Publisher
American Physical Society (APS)
Publisher DOI
Sponsorship
Engineering and Physical Sciences Research Council (EP/L015978/1)
Engineering and Physical Sciences Research Council (EP/L504920/1)
Engineering and Physical Sciences Research Council (EP/L504920/1)
Winton Programme for the Physics of Sustainability, Gates Cambridge, Oppenheimer PhD studentship, NanoDTC Cambridge (Grant ID: EP/L015978/1), Engineering and Physical Sciences Research Council (Grant ID: EP/L504920/1), Royal Society