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Cognition in people with Prader-Willi syndrome: Insights into genetic influences on cognitive and social development.

Accepted version
Peer-reviewed

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Authors

Whittington, Joyce 

Abstract

We present a mini-review of cognition in Prader-Willi syndrome. Studies cited include findings on general ability (IQ), IQ correlates with family members, strengths and weaknesses in cognitive profiles in genetic subtypes, attainment in literacy and numeracy, language, comprehension, modality preferences, executive functions, and social cognition. The latter includes investigations of theory of mind, emotion recognition, face processing and knowledge of social norms. Results from research on mouse models and brain imaging studies relevant to cognition are briefly discussed. The importance of these studies to understanding and managing education and behaviour in PWS and the limitations of the studies in terms of small numbers, non-representativeness, and lack of replication is also touched upon.

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Keywords

Ability, Attainment, Cognition, Prader-Willi syndrome, Social cognition, Animals, Cognition, Cognition Disorders, Humans, Prader-Willi Syndrome, Social Behavior, Social Change

Journal Title

Neurosci Biobehav Rev

Conference Name

Journal ISSN

0149-7634
1873-7528

Volume Title

72

Publisher

Elsevier BV