Associations Between Fetal Imprinted Genes and Maternal Blood Pressure in Pregnancy
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Abstract
In addition to maternal genes and environmental exposures, variation in fetal imprinted genes could also affect maternal blood pressure during pregnancy. Our objective was to test the associations between polymorphic variants in 16 imprinted genes and maternal mean arterial blood pressures in 1160 DNA trios from 2 established birth cohorts (the Cambridge Baby Growth and Wellbeing Studies) and seek replication in 1367 Hyperglycemia and Adverse Pregnancy Outcome Study participants. Significant univariate associations, all independent of fetal sex, were observed in the Cambridge cohorts, including
Description
Keywords
Journal Title
Conference Name
Journal ISSN
1524-4563
Volume Title
Publisher
Publisher DOI
Sponsorship
National Institute for Health Research (NIHR) (unknown)
National Institute for Health Research (NIHR) (via West Anglia Comprehensive Local Research Network (CLRN)) (UKCRN 11822)
MRC Epidemiology Unit (7500001180)
Mothercare Charitable Foundation (unknown)
Medical Research Council (MC_UU_12015/2)
Medical Research Council (G0600717)
Diabetes UK (11/0004241)
Medical Research Council (MC_U106179472)
Medical Research Council (G0600717/1)