Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer
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Peer-reviewed
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Abstract
We have previously reported that the negative signaling regulator Similar Expression to FGF (hSef) is downregulated in prostate cancer and its loss is associated with clinical metastasis. Here, we explored the mechanistic basis of this finding. We first confirmed our clinical observation by testing hSef manipulation in an
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1097-0215