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Recent advances in epilepsy

Published version
Peer-reviewed

Type

Article

Change log

Authors

Manford, M 

Abstract

This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression.

Description

Keywords

epilepsy, classification, status epilepticus, treatment, pregnancy, epileptogenesis

Journal Title

Journal of Neurology

Conference Name

Journal ISSN

0340-5354
1432-1459

Volume Title

Publisher

Springer