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Impact of maternal obesity and diabetes on long-term health of the offspring.

Published version
Peer-reviewed

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Type

Article

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Authors

Maric-Bilkan, Christine 
Symonds, Michael 
Alexander, Barbara T 

Abstract

The initial observations of David Barker, popularly known as the “Barker hypothesis” or “developmental origins of health and disease,” show that being born with low birth weight, as a result of intrauterine growth restriction produced by maternal undernutrition, is associated with a number of chronic diseases later in life [1]. Subsequently, studies show that it is not just intrauterine growth restriction, but also exposure to any other adverse factor during fetal and/or early postnatal development that can increase susceptibility to a number of chronic diseases later in life including cardiovascular and renal disease, hypertension, type 2 diabetes, certain forms of cancer, osteoporosis, Parkinson’s disease, dementia, and polycystic ovary syndrome [2–4]

Description

Keywords

Adult Children, Diabetes, Gestational, Female, Health Status, Humans, Male, Maternal Nutritional Physiological Phenomena, Obesity, Overweight, Pregnancy, Pregnancy in Diabetics

Journal Title

Experimental Diabetes Research

Conference Name

Journal ISSN

1687-5303
1687-5303

Volume Title

2011

Publisher

Hindawi Publishing Corporation
Sponsorship
Medical Research Council (G0600717)
Medical Research Council (G0600717/1)