Research data supporting "A fragment-based approach to targeting IMPDH from Mycobacterium tuberculosis"
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Authors
Trapero, Ana
Paccito, Angela
Singh, Vinayak
Sabbah, Mohamad
Description
Characterisation data for the paper 'A fragment-based approach to targeting IMPDH from Mycobacterium tuberculosis'. NMR, LCMS, HRMS for all compounds in the paper. IC50 curves for compounds screened against IMPDH from Mtb.
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NMR, LCMS, HRMS, IC50
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This work was supported by the Bill and Melinda Gates Foundation (Hit-TB) and FP7 European Project MM4TB Grant no. 260872. D.B.A was supported by a C. J. Martin Research Fellowship from the National Health and Medical Research Council of Australia (APP1072476) and the Jack Brockhoff Foundation (JBF 4186, 2016). D.B.A. and T.L.B. were also funded by a Newton Fund RCUK-CONFAP Grant awarded by The Medical Research Council and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (MR/M026302/1). V.M. and V.S. were also supported by grants from the HHMI (Senior International Research Scholars grant to V.M.), the South African Medical Research Council and the National Research Foundation.