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ComplexViewer: visualization of curated macromolecular complexes.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Combe, Colin W 
Sivade, Marine Dumousseau 
Hermjakob, Henning 
Heimbach, Joshua 
Meldal, Birgit HM 

Abstract

SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. CONTACT: colin.combe@ed.ac.uk or juri.rappsilber@ed.ac.uk.

Description

Keywords

Computational Biology, Macromolecular Substances, Models, Biological, Protein Binding, Protein Interaction Domains and Motifs, Protein Interaction Maps, Software

Journal Title

Bioinformatics

Conference Name

Journal ISSN

1367-4803
1367-4811

Volume Title

33

Publisher

Oxford University Press (OUP)
Sponsorship
BBSRC (via European Molecular Biology Laboratory (EMBL)) (CID:1861-MIDAS)