Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Wilson, Hayley
Török, M Estée
Abstract
Antimicrobial resistance (AMR) is a global public-health emergency, which threatens the advances made by modern medical care over the past century. The World Health Organization has recently published a global priority list of antibiotic-resistant bacteria, which includes extended-spectrum β-lactamase-producing Enterobacteriaceae and carbapenemase-producing Enterobacteriaceae. In this review, we highlight the mechanisms of resistance and the genomic epidemiology of these organisms, and the impact of AMR.
Description
Keywords
CPE, ESBL, Enterobacteriaceae, Gram-negative, antimicrobial resistance, Anti-Bacterial Agents, Antimicrobial Stewardship, Bacterial Proteins, Carbapenem-Resistant Enterobacteriaceae, Drug Resistance, Multiple, Bacterial, Enterobacteriaceae, Enterobacteriaceae Infections, Genes, Bacterial, Humans, Molecular Epidemiology, Prevalence, Whole Genome Sequencing, beta-Lactamases
Journal Title
Microb Genom
Conference Name
Journal ISSN
2057-5858
2057-5858
2057-5858
Volume Title
4
Publisher
Microbiology Society
Publisher DOI
Sponsorship
Academy of Medical Sciences (unknown)
Medical Research Council (MR/N029399/1)
Medical Research Council (MR/N029399/1)
The Academy of Medical Sciences, the Health Foundation, and the NIHR Cambridge Biomedical Research Centre.