Humoral alloimmunity in cardiac allograft rejection
Repository URI
Repository DOI
Change log
Authors
Alsughayyir, Jawaher
Abstract
Although the short-term outcomes of solid allograft survival have improved substantially over the last few decades, there has been no significant improvement in long-term survival of solid allografts. This thesis presents the initial characterisation of alloantibody mediated rejection in a murine heart transplant model, with particular focus on the impact of the different phases of the humoral alloimmune response (follicular or germinal centre) on graft rejection.
Description
Date
2018-07-12
Advisors
Pettigrew, Gavin
Keywords
Transplantation, antibody-mediated rejection, rejection, organ transplantation
Qualification
Doctor of Philosophy (PhD)
Awarding Institution
University of Cambridge