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Under Pressure: When a Transformed Environment Pushes Cells to Malignancy.

Accepted version
Peer-reviewed

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Authors

García-Fernández, M 
Mendez-Ferrer, Simon  ORCID logo  https://orcid.org/0000-0002-9805-9988

Abstract

Mesenchymal stem/progenitor cells (MSPCs) have recently gained attention as key elements that contribute to different stages of oncogenesis, from predisposition to disease manifestation and evolution. In this issue of Cell Stem Cell, Zambetti et al. (2016) propose a mechanism by which mutated MSPCs transform hematopoietic cells into a malignant-prone state.

Description

Keywords

Carcinogenesis, Cells, Cultured, Hematopoietic Stem Cells, Humans, Mesenchymal Stem Cells

Journal Title

Cell Stem Cell

Conference Name

Journal ISSN

1934-5909
1875-9777

Volume Title

19

Publisher

Elsevier
Sponsorship
Medical Research Council (MC_PC_12009)
European Research Council (648765)
Medical Research Council (MC_PC_12009), European Research Council (648765)