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Adaptive Behaviour and Cognitive Skills: Stability and Change from 7 Months to 7 Years in Siblings at High Familial Risk of Autism Spectrum Disorder.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Shephard, Elizabeth 
Milosavljevic, Bosiljka 
Johnson, Mark H 
Charman, Tony 

Abstract

Cognitive and adaptive behaviour abilities early in life provide important clinical prognostic information. We examined stability of such skills in children at high familial risk for ASD who either met diagnostic criteria for ASD at age 7 years (HR-ASD, n = 15) or did not (HR-non-ASD, n = 24) and low-risk control children (LR, n = 37), prospectively studied from infancy. For both HR groups, cognitive skills were consistently lower across time than those of LR children. HR-ASD children showed increasing difficulties in adaptive behaviour over time compared to LR children, while the HR-non-ASD children showed no such difficulties. This pattern of change may inform our understanding of developmental profiles of HR siblings beyond core ASD symptoms.

Description

Keywords

Adaptive behaviour, Cognitive ability, High familial risk, Prospective study, Adaptation, Psychological, Autism Spectrum Disorder, Child, Child, Preschool, Cognition, Female, Humans, Infant, Male, Risk Factors, Siblings, Social Skills

Journal Title

J Autism Dev Disord

Conference Name

Journal ISSN

0162-3257
1573-3432

Volume Title

48

Publisher

Springer Science and Business Media LLC
Sponsorship
Medical Research Council (G0600977)
Medical Research Council (MR/K021389/1)
Medical Research Council (G0701484)