ANCA Renal Risk Score: is prediction of end-stage renal disease at baseline possible?
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Kronbichler, Andreas https://orcid.org/0000-0002-2945-2946
Jayne, David RW
Abstract
Despite improved overall prognosis of patients with ANCA-associated vasculitis (AAV), those presenting with impaired renal function remain at risk of developing end-stage renal disease (ESRD). In addition to its role in diagnosis, renal histology provides prognostic information that has permitted definition of subgroups with differing risks of ESRD. In this issue, Brix et al. have developed and validated a risk score to predict the probability of ESRD. Against a background of outcome prediction in AAV, this commentary assesses different approaches to histologic risk and to what extent they assist with decisions on patient management.
Description
Keywords
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Antibodies, Antineutrophil Cytoplasmic, Glomerulonephritis, Humans, Kidney, Kidney Failure, Chronic
Journal Title
Kidney Int
Conference Name
Journal ISSN
0085-2538
1523-1755
1523-1755
Volume Title
94
Publisher
Elsevier
Publisher DOI
Sponsorship
DRWJ has received research grants from Chemocentryx, GSK, and Roche/Genentech