Cap control: cyclic versus linear oligomerisation in covalent template-directed synthesis.
Published version
Peer-reviewed
Repository URI
Repository DOI
Type
Article
Change log
Authors
Núñez-Villanueva, Diego https://orcid.org/0000-0002-1005-1464
Ciaccia, Maria
Hunter, Christopher A https://orcid.org/0000-0002-5182-1859
Abstract
Covalent template-directed synthesis was used to oligomerise monomer building blocks in a controlled manner to give exclusively the linear trimer. Competing reaction pathways were blocked by addition of a large excess of a monomeric capping agent. At a concentration of 1 mM, the cap selectively prevented further reaction of the product chain ends to give polymeric and macrocyclic products, but did not interfere with the templating process.
Description
Keywords
3405 Organic Chemistry, 34 Chemical Sciences
Journal Title
RSC Adv
Conference Name
Journal ISSN
2046-2069
2046-2069
2046-2069
Volume Title
9
Publisher
Royal Society of Chemistry (RSC)
Publisher DOI
Sponsorship
Engineering and Physical Sciences Research Council (EP/P027067/1)
Engineering and Physical Sciences Research Council (EP/P027067/1), Herchel Smith Fund.