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Social Isolation and Cognitive Function in Later Life: A Systematic Review and Meta-Analysis.

Published version
Peer-reviewed

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Type

Article

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Authors

Evans, Isobel EM 
Martyr, Anthony 
Collins, Rachel 
Clare, Linda 

Abstract

BACKGROUND: There is some evidence to suggest that social isolation may be associated with poor cognitive function in later life. However, findings are inconsistent and there is wide variation in the measures used to assess social isolation. OBJECTIVE: We conducted a systematic review and meta-analysis to investigate the association between social isolation and cognitive function in later life. METHODS: A search for longitudinal studies assessing the relationship between aspects of social isolation (including social activity and social networks) and cognitive function (including global measures of cognition, memory, and executive function) was conducted in PsycInfo, CINAHL, PubMed, and AgeLine. A random effects meta-analysis was conducted to assess the overall association between measures of social isolation and cognitive function. Sub-analyses investigated the association between different aspects of social isolation and each of the measures of cognitive function. RESULTS: Sixty-five articles were identified by the systematic review and 51 articles were included in the meta-analysis. Low levels of social isolation characterized by high engagement in social activity and large social networks were associated with better late-life cognitive function (r = 0.054, 95% CI: 0.043, 0.065). Sub-analyses suggested that the association between social isolation and measures of global cognitive function, memory, and executive function were similar and there was no difference according to gender or number of years follow-up. CONCLUSIONS: Aspects of social isolation are associated with cognitive function in later life. There is wide variation in approaches to measuring social activity and social networks across studies which may contribute to inconsistencies in reported findings.

Description

Keywords

Aging, cognition, cognitive reserve, social isolation

Journal Title

Journal of Alzheimer's Disease

Conference Name

Journal ISSN

1387-2877
1875-8908

Volume Title

70

Publisher

IOS Press
Sponsorship
Alzheimer's Society (226 (AS-DTC-2014-027))
Economic and Social Research Council (ES/G035954/1)
We are grateful to the Alzheimer’s Society for funding a PhD scholarship for Isobel Evans to complete this work through the following grant: Transdisciplinary training for dementia research in CFAS (The Alzheimer’s Society CFAS Doctoral Training Centre). 2015–2018. AS-DTC-2014-027.