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ODE-and PDE-based modeling of biological transportation networks

Accepted version
Peer-reviewed

Type

Article

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Authors

Haskovec, J 
Kreusser, LM 
Markowich, P 

Abstract

We study the global existence of solutions of a discrete (ODE based) model on a graph describing the formation of biological transportation networks, introduced by Hu and Cai. We propose an adaptation of this model so that a macroscopic (PDE based) system can be obtained as its formal continuum limit. We prove the global existence of weak solutions of the macroscopic PDE model. Finally, we present results of numerical simulations of the discrete model, illustrating the convergence to steady states, their non-uniqueness as well as their dependence on initial data and model parameters.

Description

Keywords

Weak solutions, energy dissipation, continuum limit, pattern formation, numerical modeling

Journal Title

Communications in Mathematical Sciences

Conference Name

Journal ISSN

1539-6746
1945-0796

Volume Title

17

Publisher

International Press of Boston

Rights

All rights reserved