Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster.
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Peer-reviewed
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Abstract
Highlights•FGF21 increases glucose and lipid uptake in adipose tissue.•The selective FGF21-induced increase in lipid uptake in BAT may fuel thermogenesis.•Unlike BAT, glucose uptake in WAT may be used for lipogenesis.
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Brown adipose tissue, Glucose uptake, White Adipose Tissue, Fgf21, Lipid Uptake, Β-klotho
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2212-8778
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Biotechnology and Biological Sciences Research Council (BB/M001555/1)