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INTERFEROME: the database of interferon regulated genes.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Samarajiwa, Shamith A 
Forster, Sam 
Auchettl, Katie 
Hertzog, Paul J 

Abstract

INTERFEROME is an open access database of types I, II and III Interferon regulated genes (http://www.interferome.org) collected from analysing expression data sets of cells treated with IFNs. This database of interferon regulated genes integrates information from high-throughput experiments with annotation, ontology, orthologue sequences from 37 species, tissue expression patterns and gene regulatory information to enable a detailed investigation of the molecular mechanisms underlying IFN biology. INTERFEROME fulfils a need in infection, immunity, development and cancer research by providing computational tools to assist in identifying interferon signatures in gene lists generated by high-throughput expression technologies, and their potential molecular and biological consequences.

Description

Keywords

Animals, Databases, Genetic, Gene Expression Profiling, Gene Expression Regulation, Humans, Interferons, Mice, Oligonucleotide Array Sequence Analysis, Promoter Regions, Genetic, Proteomics

Journal Title

Nucleic Acids Res

Conference Name

Journal ISSN

0305-1048
1362-4962

Volume Title

37

Publisher

Oxford University Press (OUP)