Spleen Size Does Not Correlate With Histological Stage of Liver Disease in People With Nonalcoholic Fatty Liver Disease.
Accepted version
Peer-reviewed
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Repository DOI
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Authors
Cacciottolo, Tessa M
Kumar, Anupa
Godfrey, Edmund M
Davies, Susan E
Allison, Michael
Abstract
Splenomegaly in the context of liver disease is classically associated with advanced cirrhosis and portal hypertension.1 More recently, we observed an increasing number of patients with splenomegaly and nonalcoholic fatty liver disease (NAFLD), but in whom intensive work-up revealed no evidence of advanced liver disease or portal hypertension. In this study, we found no correlation between spleen size and histological stage of NAFLD, and a strong correlation between body weight, height and serum high density lipoprotein (HDL) levels.
Description
Keywords
Humans, Non-alcoholic Fatty Liver Disease, Spleen, Splenomegaly, Liver, Liver Cirrhosis, Hypertension, Portal
Journal Title
Clin Gastroenterol Hepatol
Conference Name
Journal ISSN
1542-3565
1542-7714
1542-7714
Volume Title
75
Publisher
Elsevier BV