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Impact of the intrauterine environment on future reproductive and metabolic health

Published version
Peer-reviewed

Change log

Authors

Dunkerton, Suzanna 

Abstract

jats:secjats:titleKey content</jats:title>jats:p <jats:list list-type="bullet">

jats:list-itemjats:pAs survival of babies born following high‐risk pregnancies continues to increase globally, understanding the long‐term impacts of suboptimal intrauterine environments on future health becomes increasingly important.</jats:p></jats:list-item>

jats:list-itemjats:pThe intrauterine environment is a key influence on later metabolic health, particularly the tendency to later‐life obesity and dyslipidaemia.</jats:p></jats:list-item>

jats:list-itemjats:pRecent evidence shows that female reproductive function is also highly sensitive to the influence of the early life environment.</jats:p></jats:list-item>

jats:list-itemjats:pVarious suboptimal intrauterine environments are linked to adverse reproductive and metabolic outcomes, including maternal obesity, low‐protein diets and chronic fetal hypoxia.</jats:p></jats:list-item> </jats:list> </jats:p></jats:sec>jats:secjats:titleLearning objectives</jats:title>jats:p <jats:list list-type="bullet">

jats:list-itemjats:pTo know that the prevalence of high‐risk intrauterine environments is increasing in maternity populations because of, for example, increasing rates of maternal obesity.</jats:p></jats:list-item>

jats:list-itemjats:pTo be aware of the later‐life health implications for the fetus when caring for women with high‐risk pregnancies.</jats:p></jats:list-item>

jats:list-itemjats:pTo understand that children who are survivors of high‐risk pregnancies are at increased risk of adverse metabolic health outcomes and more work is required to determine optimal follow‐up.</jats:p></jats:list-item> </jats:list> </jats:p></jats:sec>

Description

Keywords

developmental programming, high-risk pregnancy, intrauterine environment, metabolic health, reproductive health

Journal Title

OBSTETRICIAN & GYNAECOLOGIST

Conference Name

Journal ISSN

1467-2561
1744-4667

Volume Title

Publisher

Wiley