Research data supporting "Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner"
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Dataset
Change log
Authors
Carminatti Pantaleao, Lucas https://orcid.org/0000-0002-5626-8810
Inzani, Isabella
Description
The xlsx file contains a collection of datasets characterizing the cardiac phenotype and the cardiac and circulatory lipid profiles in late gestation E18.5 fetuses of diet-induced obese pregnant mice. These several datasets contain the processed data used in the article "Maternal diet-induced obesity during pregnancy alters lipid supply to mouse E18.5 fetuses and changes the cardiac tissue lipidome in a sex-dependent manner", published on eLife (doi: 10.7554/eLife.69078) Datasets are separated in tabs with a brief description of the data, as well as outlier allocation and criteria.
Version
Software / Usage instructions
R v.4.1.2
Ingenuity Pathways Analysis (IPA) v.42012434
edgeR v.3.36.0
QuPath v.0.3.0
Xcalibur v.4.3
Harmony v5.0
ImageJ v.1.53n
XCMS v.3.16.1
Peakpicker v.2.0
Keywords
Maternal obesity, Fetal heart, Lipidomics, Heart metabolism
Publisher
Sponsorship
This work was funded by the British Heart Foundation [RG/17/12/33167], the MRC Metabolic Diseases Unit [MRC_MC_UU_00014/4], and the Wellcome Trust [208363/Z/17/Z]. A.A.M.C was supported by a Cambridge Home and EU Student Scholarship. E.L. was supported by a British Heart Foundation studentship [FS/12/64/30001]. II was supported by a British Heart Foundation studentship [FS/18/56/35177]. S.F. was supported by the BBSRC [BB/M027252/1].