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[{"$nulls":15},"Rules used; From Paper PMID:12538249 Ma H, Zeng AP Reconstruction of metabolic networks from genome data and analysis of their global structure for various organisms"]
[null,"Row","Identifier","KEGG Identifier","Description","Equation","LB","UB","Direction Confidence",null,"Localisation Confidence","EC",null,null,null,"a) Oxygen consumption reaction"]
[null,1,"R00004MM","R00004","Pyrophosphate+H2O-->2Orthophosphate","C00013MM + C00001MM <=> 2 C00009MM",0,1000,"d,h4,i",4,"U, G1, P, M10, S, T","3.6.1.1",null,null,null,"b) CO2 production (only used as a ssubstrate when used with PEP and ATP are consumed at the same time"]
[null,2,"R00004Cyto","R00004","Pyrophosphate+H2O-->2Orthophosphate","C00013Cyto + C00001Cyto <=> 2 C00009Cyto + C00080Cyto",0,1000,"d,h4,i",{"$error":"#N/A"},"n/a","3.6.1.1",null,null,null,"c) NH3 production (except carbamoyl phosphate production)"]
[null,3,"R00009MM","R00009","2H2O2-->Oxygen+2H2O","2 C00027MM <=> C00007MM + 2 C00001MM",0,1000,"h1,i,l",14,"G2, M8, S, T","1.11.1.6",null,null,null,"d) Phosphate production (except when reacts with AcCoA"]
[null,4,"R00014MM","R00014","Pyruvate+Thiamindiphosphate-->2-(alpha-Hydroxyethyl)thiaminediphosphate+CO2","C00022MM + C00068MM + C00080MM <=> C05125MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, P, M23, S, T","1.2.4.1",null,null,null,"e) THF produced for transferring one carbon unit"]
[null,5,"R00036Cyto","R00036","25-Aminolevulinate-->Porphobilinogen+2H2O","2 C00430Cyto <=> C00931Cyto + 2 C00001Cyto + C00080Cyto",-1000,1000,"n/a",null,"n/a","4.2.1.24",null,null,null,"f) Most ATP consumption reactions and other high energy metabolites (except where GTP, CAP, acetyl phosphate, Acyl-CoA "]
[null,6,"R00081MM","R00081","COMPLEX_IV_Oxygen+4Ferrocytochromec-->4Ferricytochromec+2H2O","C00007MM + 4 C00126MM + 8 C00080MM <=> 4 C00125MM + 2 C00001MM + 4 C00080Cyto",-1000,1000,"n/a","Is complex IV","L, U, G2, B2, S, T","1.9.3.1","h4,l,m. Change stoichiometry!",null,null,"g) CDP-diacylglycerol consumption"]
[null,7,"R00084Cyto","R00084","4Porphobilinogen+H2O-->Hydroxymethylbilane+4NH3","4 C00931Cyto + C00001Cyto <=> C01024Cyto + 4 C00014Cyto",-1000,1000,"n/a",null,"n/a","2.5.1.61",null,null,null,"h1) Delta G 30kJ/mol"]
[null,8,"R00086MM","R00086","ATP_SYNTHASE_ADP+Orthophosphate+4H+-->ATP+H2O"," C00008MM + C00009MM + 2.7 C00080Cyto <=> C00002MM + C00001MM + 1.7 C00080MM",-1000,1000,"n/a","ATP Synthase","L, U, G2, B2, S, T","3.6.3.14","Brenda says opposite",null,null,"h2) Delta G 20kJ/mol"]
[null,9,"R00094MM","R00094","2Glutathione+NAD+-->Glutathionedisulfide+NADH+H+","2 C00051MM + C00003MM <=> C00127MM + C00004MM + C00080MM",-1000,0,"i,k","Brenda, stops loop with R00115","U, G1, P, M8, B2, S, T","1.8.1.7",null,null,null,"h3) Delta G 10kJ/mol"]
[null,10,"R00112MM","R00112","NADPH+NAD+-->NADP++NADH","C00005MM + C00003MM <=> C00006MM + C00004MM",-1000,0,"i,j","Ec with evidence is only '-> in Kegg","U, G2, M9, B2, S, T","1.6.1.2",null,null,null,"h4) Delta G 5kJ/mol"]
[null,11,"R00115MM","R00115","2Glutathione+NADP+-->Glutathionedisulfide+NADPH+H+","2 C00051MM + C00006MM <=> C00127MM + C00005MM + C00080MM",-1000,0,"i,k,l,n","14, Brenda, stops loop with R00115","U, G1, P, M8, B2, S, T","1.8.1.7",null,null,null,"i) Brenda"]
[null,12,"R00127MM","R00127","ATP+AMP-->2ADP","C00002MM + C00020MM <=> 2 C00008MM",-1000,1000,"n/a",0,"U, G2, M11, S, T","2.7.4.3",null,null,null,"j) Primary literature"]
[null,13,"R00127Cyto","R00127c","ATP+AMP-->2ADP","C00002Cyto + C00020Cyto <=> 2 C00008Cyto + C00080Cyto",-1000,1000,"n/a",{"$error":"#N/A"},"n/a","2.7.4.3",null,null,null,"k) Required to stop loops"]
[null,14,"R00156MM","R00156","ATP+UDP-->ADP+UTP","C00002MM + C00015MM <=> C00008MM + C00075MM",0,1000,"f,m",0,"U, G1, P, M8, B2, S, T","2.7.4.6",null,null,null,"l) Palsson model"]
[null,15,"R00157MM","R00157","UTP+AMP-->UDP+ADP","C00075MM + C00020MM <=> C00015MM + C00008MM",-1000,1000,"n/a",0,"U, G2, M11, S, T","2.7.4.10",null,null,null,"m) Modelling purposes - prevent production of ATP etc"]
[null,16,"R00200Cyto","R00200","ATP+Pyruvate-->ADP+Phosphoenolpyruvate","C00002Cyto + C00022Cyto <=> C00008Cyto + C00074Cyto + 2 C00080Cyto",-1000,0,"i,j,l,n","Part of glycolysis","n/a","2.7.1.40",null,null,null,"n) Kegg"]
[null,17,"R00205MM","R00205","Methylglyoxal+NADP++H2O-->Pyruvate+NADPH+H+","C00546MM + C00006MM + C00001MM <=> C00022MM + C00005MM + 2 C00080MM",-1000,1000,"n/a",null,"S, T, L","1.2.1.49",null,null,null,"o) HumanCyc"]
[null,18,"R00214MM","R00214","(S)-Malate+NAD+-->Pyruvate+CO2+NADH+H+","C00149MM + C00003MM <=> C00022MM + C00011MM + C00004MM",0,1000,"b,i",2,"U, G2, M11, S, T","1.1.1.38","Brenda says opposite"]
[null,19,"R00214Cyto","R00214c","(S)-Malate+NAD+-->Pyruvate+CO2+NADH+H+","C00149Cyto + C00003Cyto <=> C00022Cyto + C00011Cyto + C00004Cyto",0,1000,"b,i",2,"n/a","1.1.1.38","Brenda says opposite",null,null,"Code for localisation"]
[null,20,"R00216MM","R00216","(S)-Malate+NADP+-->Pyruvate+CO2+NADPH+H+","C00149MM + C00006MM <=> C00022MM + C00011MM + C00005MM",0,1000,"b,l","2,14","U, G2, M11, S, T","1.1.1.38",null,null,null,"U - UniProt mitochondrion"]
[null,21,"R00233MM","R00233","Malonyl-CoA-->Acetyl-CoA+CO2","C00083MM + C00080MM <=> C00024MM + C00011MM",0,1000,"b,i,n",2,"U, G1, M5, B1, B2, S, T, ","1.1.1.9","Palsson wrong",null,null,"G1 - GO mitochondrion"]
[null,22,"R00236MM","R00236","Acetyladenylate+CoA-->AMP+Acetyl-CoA","C05993MM + C00010MM <=> C00020MM + C00024MM + C00080MM",0,1000,"h2, o",13,"U, G2, P, M7, S, T","6.2.1.1",null,null,null,"G2 - GO mitochondrial matrix"]
[null,23,"R00238MM","R00238","2Acetyl-CoA-->CoA+Acetoacetyl-CoA","2 C00024MM <=> C00010MM + C00332MM",-1000,1000,"n/a",0,"U, G2, M15, S, T","2.3.1.16","Brenda says reversible",null,null,"B1 - Brenda mitochondrion"]
[null,24,"R00239MM","R00239","ATP+L-Glutamate-->ADP+L-Glutamyl5-phosphate","C00002MM + C00025MM <=> C00008MM + C03287MM",0,1000,"f,i,n","7 does not apply as acetyl phosphate involved. Brenda says is this direction","U, G2, M6, N13, B1, S, T","2.7.2.11",null,null,null,"B2 - Brenda mitochondrial matrix"]
[null,25,"R00243MM","R00243","L-Glutamate+NAD++H2O-->2-Oxoglutarate+NH3+NADH+H+","C00025MM + C00003MM + C00001MM <=> C00026MM + C00014MM + C00004MM + C00080MM",0,1000,"c,k","Not convinced 3 applies as against thermodynamics. Need to stop loop with R00248","U, G2, M18, S, T","1.4.1.3","Brenda says reversible",null,null,"P - GFP evidence"]
[null,26,"R00245MM","R00245","L-Glutamate5-semialdehyde+NAD++H2O-->L-Glutamate+NADH+H+","C01165MM + C00003MM + C00001MM <=> C00025MM + C00004MM + 2 C00080MM",0,1000,"i,j,o","13, need to stop loop with R03314, R00245 and R00708","U, G2, M16, S, T","1.5.1.12",null,null,null,"M - Number of MS studies"]
[null,27,"R00248MM","R00248","L-Glutamate+NADP++H2O-->2-Oxoglutarate+NH3+NADPH+H+","C00025MM + C00006MM + C00001MM <=> C00026MM + C00014MM + C00005MM + C00080MM",0,1000,"c,k","Not convinced 3 applies as against thermodynamics. Need to stop loop with R00243","U, G2, M18, S, T","1.4.1.3",null,null,null,"N - Number of MS experiments"]
[null,28,"R00256MM","R00256","L-Glutamine+H2O-->L-Glutamate+NH3","C00064MM + C00001MM <=> C00025MM + C00014MM",-1000,1000,"n/a",3,"U, G2, M2, S, T","3.5.1.2",null,null,null,"T - Tissue (Brenda or MS study)"]
[null,29,"R00258MM","R00258","L-Alanine+2-Oxoglutarate-->Pyruvate+L-Glutamate","C00041MM + C00026MM <=> C00022MM + C00025MM",-1000,0,"j,m",0,"U, G2, M8, S, T","2.6.1.2",null,null,null,"S - Species (Brenda or MS study)"]
[null,30,"R00261MM","R00261","L-Glutamate-->4-Aminobutanoate+CO2","C00025MM + C00080MM <=> C00334MM + C00011MM",0,1000,"b,i,n",2,"M2, B1, S","4.1.1.15","not in brenda",null,null,"L - Literature mitochondrial"]
[null,31,"R00268MM","R00268","Oxalosuccinate+NADP+-->2-Oxoglutarate+CO2+NADPH+H+","C05379MM + C00080MM <=> C00026MM + C00011MM",0,1000,"b",2,"U, G2, P, M10, S, T","1.1.1.42"]
[null,32,"R00274MM","R00274","H2O2+2Glutathione-->Glutathionedisulfide+2H2O","C00027MM + 2 C00051MM <=> C00127MM + 2 C00001MM",0,1000,"h1,i,n",12,"G1, M8, B1, B2, S, T ","1.11.1.9"]
[null,33,"R00275MM","R00275","2O2.-+2H+-->H2O2+Oxygen","2 C00704MM + 2 C00080MM <=> C00027MM + C00007MM",0,1000,"l,i",14,"U, G2, M19, S, T","1.15.1.1"]
[null,34,"R00310MM","R00310","Protoporphyrin+Fe2+-->Heme+2H+","C02191MM + C14818MM <=> C00032MM + 2 C00080MM",0,1000,"l,i,n",14,"U, G2, M8, S, T","4.99.1.1"]
[null,35,"R00316MM","R00316","ATP+Acetate-->Pyrophosphate+Acetyladenylate","C00002MM + C00033MM <=> C00013MM + C05993MM",-1000,1000,"n/a","13 does not apply as 2 step of reaction is negative enough to cover","U, G2, P, M7, S","6.2.1.1"]
[null,36,"R00330MM","R00330","ATP+GDP-->ADP+GTP","C00002MM + C00035MM <=> C00008MM + C00044MM",-1000,1000,"n/a",0,"U, G1, P, M8, B2, S, T","2.7.4.6"]
[null,37,"R00342MM","R00342","(S)-Malate+NAD+-->Oxaloacetate+NADH+H+","C00149MM + C00003MM <=> C00036MM + C00004MM + C00080MM",0,1000,"j,m","Part of malate aspartate shuttle","U, G2, P, M22, S, T","1.1.1.37"]
[null,38,"R00342Cyto","R00342c","(S)-Malate+NAD+-->Oxaloacetate+NADH+H+","C00149Cyto + C00003Cyto <=> C00036Cyto + C00004Cyto + C00080Cyto",-1000,0,"j,m","Part of malate aspartate shuttle","n/a","1.1.1.37"]
[null,39,"R00344MM","R00344","ATP+Pyruvate+HCO3--->ADP+Orthophosphate+Oxaloacetate","C00002MM + C00022MM + C00288MM <=> C00008MM + C00009MM + C00036MM + C00080MM",0,1000,"f,i,l,n","7,14","U, G2, M9, S, T","6.4.1.1"]
[null,40,"R00351MM","R00351","Citrate+CoA-->Acetyl-CoA+H2O+Oxaloacetate","C00158MM + C00010MM + C00080MM <=> C00024MM + C00001MM + C00036MM",-1000,0,"h4,i,l",14,"U, G2, M14, S, T","2.3.3.1"]
[null,41,"R00355MM","R00355","L-Aspartate+2-Oxoglutarate-->Oxaloacetate+L-Glutamate","C00049MM + C00026MM <=> C00036MM + C00025MM",-1000,0,"j,m","Part of malate aspartate shuttle","U, G2, M17, S, T","2.6.1.1"]
[null,42,"R00355Cyto","R00355c","L-Aspartate+2-Oxoglutarate-->Oxaloacetate+L-Glutamate","C00049Cyto + C00026Cyto <=> C00036Cyto + C00025Cyto",0,1000,"j,m","Part of malate aspartate shuttle","n/a","2.6.1.1"]
[null,43,"R00371MM","R00371","Acetyl-CoA+Glycine-->CoA+L-2-Amino-3-oxobutanoicacid","C00024MM + C00037MM <=> C00010MM + C03508MM + C00080MM",-1000,1000,"n/a",0,"U, G2, P, M3, S","2.3.1.37"]
[null,44,"R00388MM","R00388","Acyl-CoA+Oxygen-->trans-2,3-Dehydroacyl-CoA+H2O2","C00040MM + C00007MM <=> C00658MM + C00027MM",-1000,1000,"n/a","Odd reaction - really produce H2O2 in vivo","G1, M4, B1, S, T","1.3.3.6"]
[null,45,"R00391MM","R00391","Acyl-CoA+Acetyl-CoA-->CoA+3-Oxoacyl-CoA","C00040MM + C00024MM <=> C00010MM + C00264MM",-1000,1000,"n/a","To make TCA (R00351) to work","U, G2, M14, B2, S, T","2.3.1.16","Reversible in brenda"]
[null,46,"R00405MM","R00405","ATP+Succinate+CoA-->ADP+Orthophosphate+Succinyl-CoA","C00002MM + C00042MM + C00010MM <=> C00008MM + C00009MM + C00091MM",-1000,0,"m","Required to stop ATP production","U, G2, P, M14, S, T","6.2.1.5"]
[null,47,"R00410MM","R00410","Succinyl-CoA+Acetoacetate-->Succinate+Acetoacetyl-CoA","C00091MM + C00164MM <=> C00042MM + C00332MM",0,1000,"i,j,o,k,m",0,"U, G2, M9, S, T","2.8.3.5"]
[null,48,"R00430MM","R00430","GTP+Pyruvate-->GDP+Phosphoenolpyruvate","C00044MM + C00022MM <=> C00035MM + C00074MM + C00080MM",-1000,1000,"n/a",0,"M8, S, T","2.7.1.40"]
[null,49,"R00431MM","R00431","GTP+Oxaloacetate-->GDP+Phosphoenolpyruvate+CO2","C00044MM + C00036MM <=> C00035MM + C00074MM + C00011MM",0,1000,"f,i,l,n","7,14","U, G1, P, M7, S, T","4.1.1.32"]
[null,50,"R00432MM","R00432","GTP+Succinate+CoA-->GDP+Orthophosphate+Succinyl-CoA","C00044MM + C00042MM + C00010MM <=> C00035MM + C00009MM + C00091MM",-1000,1000,"n/a","TCA cycle so can produce GTP","U, G1, G2, M9, S, T","6.2.1.4"]
[null,51,"R00512MM","R00512","ATP+CMP-->ADP+CDP","C00002MM + C00055MM <=> C00008MM + C00112MM",-1000,1000,"n/a",0,"U, G1, P, B1, S","2.7.4.14"]
[null,52,"R00551MM","R00551","L-Arginine+H2O-->L-Ornithine+Urea","C00062MM + C00001MM <=> C00077MM + C00086MM",0,1000,"i,k,n,o",0,"U, G1, M3, B1, L, S, T","3.5.3.1"]
[null,53,"R00566MM","R00566","L-Arginine-->Agmatine+CO2","C00062MM + C00080MM <=> C00179MM + C00011MM",0,1000,"b,i,n",2,"G1, B2, S","4.1.1.19","Opposite in brenda"]
[null,54,"R00570MM","R00570","ATP+CDP-->ADP+CTP","C00002MM + C00112MM <=> C00008MM + C00063MM",0,1000,"a,i",0,"U, G1, P, M8, B2, T , S","2.7.4.6"]
[null,55,"R00572MM","R00572","CTP+Pyruvate-->CDP+Phosphoenolpyruvate","C00063MM + C00022MM <=> C00112MM + C00074MM + C00080MM",-1000,1000,"n/a",0,"M8, S, T","2.7.1.40"]
[null,56,"R00621MM","R00621","2-Oxoglutarate+Thiamindiphosphate-->3-Carboxy-1-hydroxypropyl-ThPP+CO2","C00026MM + C00068MM + C00080MM <=> C05381MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, P, M19, S, T","1.2.4.2"]
[null,57,"R00658Cyto","R00658","2-Phospho-D-glycerate-->Phosphoenolpyruvate+H2O","C00631Cyto <=> C00074Cyto + C00001Cyto",-1000,1000,"n/a",0,"n/a","4.2.1.11"]
[null,58,"R00659MM","R00659","UTP+Pyruvate-->UDP+Phosphoenolpyruvate","C00075MM + C00022MM <=> C00015MM + C00074MM + C00080MM",-1000,0,"i,k,m","Brenda says this direction and needed to prevent production of pyruvate","G1, M8, S, T","2.7.1.40"]
[null,59,"R00667MM","R00667","L-Ornithine+2-Oxoglutarate-->L-Glutamate5-semialdehyde+L-Glutamate","C00077MM + C00026MM <=> C01165MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M12, S, T","2.6.1.13"]
[null,60,"R00703Cyto","R00703","(S)-Lactate+NAD+-->Pyruvate+NADH+H+","C00186Cyto + C00003Cyto <=> C00022Cyto + C00004Cyto + C00080Cyto",-1000,1000,"n/a",{"$error":"#N/A"},"M6, N12, B2, S, T","1.1.1.27"]
[null,61,"R00705MM","R00705","3-Oxopropanoate+CoA+NAD+-->Acetyl-CoA+CO2+NADH+H+","C00222MM + C00010MM + C00003MM <=> C00024MM + C00011MM + C00004MM",0,1000,"b,h4,i,n",2,"U, G1, M11, B2, S, T","1.2.1.18"]
[null,62,"R00706MM","R00706","3-Oxopropanoate+CoA+NADP+-->Acetyl-CoA+CO2+NADPH+H+","C00222MM + C00010MM + C00006MM <=> C00024MM + C00011MM + C00005MM",0,1000,"b,h4,i,n",2,"U, G1, M11, B2, S, T","1.2.1.18"]
[null,63,"R00707MM","R00707","(S)-1-Pyrroline-5-carboxylate+NAD++2H2O-->L-Glutamate+NADH+H+","C03912MM + C00003MM + 2 C00001MM <=> C00025MM + C00004MM + C00080MM",0,1000,"i,o",null,"U, G2, B2, P, M16, S, T","1.5.1.12"]
[null,64,"R00708MM","R00708","(S)-1-Pyrroline-5-carboxylate+NADP++2H2O-->L-Glutamate+NADPH+H+","C03912MM + C00006MM + 2 C00001MM <=> C00025MM + C00005MM + C00080MM",0,1000,"i,o",null,"U, G2, B2, P, M16, S, T","1.5.1.12"]
[null,65,"R00709MM","R00709","Isocitrate+NAD+-->2-Oxoglutarate+CO2+NADH+H+","C00311MM + C00003MM <=> C00026MM + C00011MM + C00004MM",0,1000,"b,i,j,l","TCA cycle","U, G2, P, M11, S, T","1.1.1.41"]
[null,66,"R00710MM","R00710","Acetaldehyde+NAD++H2O-->Acetate+NADH+H+","C00084MM + C00003MM + C00001MM <=> C00033MM + C00004MM +  2 C00080MM",0,1000,"h3,i","13,Brenda","U, G2, P, M18, S, T","1.2.1.3"]
[null,67,"R00711MM","R00711","Acetaldehyde+NADP++H2O-->Acetate+NADPH+H+","C00084MM + C00006MM + C00001MM <=> C00033MM + C00005MM + 2 C00080MM",0,1000,"h3,i","13,Brenda","U, G2, P, M18, S, T","1.2.1.3"]
[null,68,"R00713MM","R00713","Succinatesemialdehyde+NAD++H2O-->Succinate+NADH+H+","C00232MM + C00003MM + C00001MM <=> C00042MM + C00004MM + 2 C00080MM",-1000,1000,"n/a",0,"U, G1, M5, N24, B2, S, T","1.2.1.24"]
[null,69,"R00716MM","R00716","N6-(L-1,3-Dicarboxypropyl)-L-lysine+NADP++H2O-->L-Lysine+2-Oxoglutarate+NADPH+H+","C00449MM + C00006MM + C00001MM <=> C00047MM + C00026MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"U, G1, M4, B2, S, T","1.5.1.8"]
[null,70,"R00722MM","R00722","ATP+IDP-->ADP+ITP","C00002MM + C00104MM <=> C00008MM + C00081MM",0,1000,"f,i",0,"U, G1, P, M8, B2, S, T","2.7.4.6","not in brenda"]
[null,71,"R00724MM","R00724","ITP+Pyruvate-->IDP+Phosphoenolpyruvate","C00081MM + C00022MM <=> C00104MM + C00074MM + C00080MM",-1000,0,"i,k,m","Required to stop ATP production via GTP R00430","G1, M8, S, T","2.7.1.40","not in brenda"]
[null,72,"R00726MM","R00726","L-Alanine+2-Oxoglutarate-->Pyruvate+L-Glutamate","C00081MM + C00036MM <=> C00104MM + C00074MM + C00011MM",-1000,1000,"n/a","Required to stop production of ATP from ITP (R00722)","U, G1, P, M7, B1, S, T","4.1.1.32"]
[null,73,"R00727MM","R00727","ITP+Succinate+CoA-->IDP+Orthophosphate+Succinyl-CoA","C00081MM + C00042MM + C00010MM <=> C00104MM + C00009MM + C00091MM",-1000,0,"m","Required to stop ATP production","U, G2, M9, B2, S, T","6.2.1.4"]
[null,74,"R00740MM","R00740","3-Oxopropanoate+CoA+NADP+-->Malonyl-CoA+NADPH+H+","C00222MM + C00010MM + C00006MM <=> C00083MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"U, G1, M11, S, T","1.2.1.18"]
[null,75,"R00742MM","R00742","ATP+Acetyl-CoA+HCO3--->ADP+Orthophosphate+Malonyl-CoA","C00002MM + C00024MM + C00288MM <=> C00008MM + C00009MM + C00083MM + C00080MM",0,1000,"d,f,i,n","4,7","M3, N8, B2, S, T","6.4.1.2"]
[null,76,"R00830MM","R00830","Succinyl-CoA+Glycine-->5-Aminolevulinate+CoA+CO2","C00091MM + C00037MM <=> C00430MM + C00010MM + C00011MM",0,1000,"b,i,n",2,"U, G2, P, M3, S","2.3.1.37"]
[null,77,"R00833MM","R00833","(R)-2-Methyl-3-oxopropanoyl-CoA-->Succinyl-CoA","C01213MM <=> C00091MM",-1000,1000,"n/a",0,"U, G2, M5, S, T","5.4.99.2"]
[null,78,"R00842Cyto","R00842","sn-Glycerol3-phosphate+NAD+-->Glyceronephosphate+NADH+H+","C00093Cyto + C00003Cyto <=> C00111Cyto + C00004Cyto + C00080Cyto",-1000,0,"i,j,n","Is part of the glycerol phosphate shuttle","U, G1, P, M8, B2, S","1.1.1.8"]
[null,79,"R00851MM","R00851","sn-Glycerol3-phosphate+Palmitoyl-CoA-->1-Acyl-sn-glycerol3-phosphate+CoA","C00093Cyto + C00154MM <=> C00681MM + C00010MM",-1000,1000,"n/a",0,"U, G2, M3, B2, S, T","2.3.1.15"]
[null,80,"R00895MM","R00895","L-Cysteine+2-Oxoglutarate-->Mercaptopyruvate+L-Glutamate","C00097MM + C00026MM <=> C00957MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M17, S, T","2.6.1.1","not in brenda"]
[null,81,"R00926MM","R00926","Propinoladenylate+CoA-->AMP+Propanoyl-CoA","C05983MM + C00010MM <=> C00020MM + C00100MM + C00080MM",-1000,1000,"n/a","13 and below","U, G2, P, M7, S, T","6.2.1.1"]
[null,82,"R00927MM","R00927","Propanoyl-CoA+Acetyl-CoA-->CoA+2-Methylacetoacetyl-CoA","C00100MM + C00024MM <=> C00010MM + C03344MM",-1000,1000,"n/a",0,"U, G2, M14, S, T","2.3.1.16"]
[null,83,"R00935MM","R00935","(S)-Methylmalonatesemialdehyde+CoA+NAD+-->Propanoyl-CoA+CO2+NADH+H+","C06002MM + C00010MM + C00003MM <=> C00100MM + C00011MM + C00004MM",0,1000,"b,h4,i,n,",0,"U, G1, M6, B2, S","1.2.1.27"]
[null,84,"R00941MM","R00941","10-Formyltetrahydrofolate+NADP++H2O-->Tetrahydrofolate+CO2+NADPH+H+","C00234MM + C00006MM + C00001MM <=> C00101MM + C00011MM + C00005MM + C00080MM",0,1000,"b,e,h4,i,n","2,6","M4, N12, B1, S, T","1.5.1.6"]
[null,85,"R00945MM","R00945","5,10-Methylenetetrahydrofolate+Glycine+H2O-->Tetrahydrofolate+L-Serine","C00143MM + C00037MM + C00001MM <=> C00101MM + C00065MM",-1000,1000,"n/a",0,"U, G2, P, M12, B2, S, T","2.1.2.1"]
[null,86,"R01015Cyto","R01015","D-Glyceraldehyde3-phosphate-->Glyceronephosphate","C00118Cyto <=> C00111Cyto",-1000,1000,"n/a","Part of glycolysis","n/a","5.3.1.1"]
[null,87,"R01061Cyto","R01061","D-Glyceraldehyde3-phosphate+Orthophosphate+NAD+-->3-Phospho-D-glyceroylphosphate+NADH+H+","C00118Cyto + C00009Cyto + C00003Cyto <=> C00236Cyto + C00004Cyto + C00080Cyto",-1000,1000,"n/a",0,"n/a","1.2.1.12"]
[null,88,"R01070Cyto","R01070","beta-D-Fructose1,6-bisphosphate-->Glyceronephosphate+D-Glyceraldehyde3-phosphate","C05378Cyto <=> C00111Cyto + C00118Cyto",-1000,1000,"n/a",0,"n/a","4.1.2.13"]
[null,89,"R01082MM","R01082","(S)-Malate-->Fumarate+H2O","C00149MM <=> C00122MM + C00001MM",-1000,1000,"n/a",0,"U, G2, P, M17, S, T","4.2.1.2"]
[null,90,"R01090MM","R01090","L-Leucine+2-Oxoglutarate-->4-Methyl-2-oxopentanoate+L-Glutamate","C00123MM + C00026MM <=> C00233MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M12, S, T","2.6.1.42"]
[null,91,"R01137MM","R01137","ATP+dADP-->ADP+dATP","C00002MM + C00206MM <=> C00008MM + C00131MM",0,1000,"b,i",0,"U, G1, P, M8, B2, S, T","2.7.4.6"]
[null,92,"R01138MM","R01138","dATP+Pyruvate-->dADP+Phosphoenolpyruvate","C00131MM + C00022MM <=> C00206MM + C00074MM + C00080MM",-1000,0,"i,m","Required to stop production of ITP via R00724 which generates ATP from R00722","G1, M8, S, T","2.7.1.40","Not in brenda"]
[null,93,"R01157MM","R01157","Agmatine+H2O-->Putrescine+Urea","C00179MM + C00001MM <=> C00134MM + C00086MM",-1000,1000,"n/a",0,"U, G1, M1, N4, B2, S","3.5.3.11"]
[null,94,"R01171MM","R01171","Butanoyl-CoA+NAD+-->Crotonoyl-CoA+NADH+H+","C00136MM + C00003MM <=> C00877MM + C00004MM + C00080MM",1000,0,"m","part of fatty acid metabolism so can go up hill","U, G2, M12, S, T","1.3.99.2"]
[null,95,"R01175MM","R01175","Butanoyl-CoA+FAD-->FADH2+Crotonoyl-CoA","C00136MM + C00016MM + C00080MM <=> C01352MM + C00877MM",0,1000,"i,j,m,n","part of fatty acid metabolism so can go up hill","U, G2, M16, S, T","1.3.99.3"]
[null,96,"R01176MM","R01176","ATP+Butanoicacid+CoA-->AMP+Pyrophosphate+Butanoyl-CoA","C00002MM + C00246MM + C00010MM <=> C00020MM + C00013MM + C00136MM + C00080MM",0,1000,"f,i,n",0,"U, G2, M4, B2, S, T","6.2.1.2"]
[null,97,"R01177MM","R01177","Acetyl-CoA+Butanoyl-CoA-->CoA+3-Oxohexanoyl-CoA","C00024MM + C00136MM <=> C00010MM + C05269MM",-1000,1000,"n/a",0,"U, G2, M15, S, T","2.3.1.16"]
[null,98,"R01214MM","R01214","L-Valine+2-Oxoglutarate-->3-Methyl-2-oxobutanoicacid+L-Glutamate","C00183MM + C00026MM <=> C00141MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M12, S, T","2.6.1.42"]
[null,99,"R01218MM","R01218","5,10-Methylenetetrahydrofolate+NAD+-->5,10-Methenyltetrahydrofolate+NADH+H+","C00143MM + C00003MM <=> C00445MM + C00004MM",0,1000,"i,j,o",0,"U, G1, M5, B1, S","1.5.1.15"]
[null,100,"R01220MM","R01220","5,10-Methylenetetrahydrofolate+NADP+-->5,10-Methenyltetrahydrofolate+NADPH+H+","C00143MM + C00006MM <=> C00445MM + C00005MM",0,1000,"i, o",0,"M7, N18, B1, S, T","1.5.1.5"]
[null,101,"R01248MM","R01248","L-Proline+NAD+-->(S)-1-Pyrroline-5-carboxylate+NADH+H+","C00148MM + C00003MM <=> C03912MM + C00004MM + 2 C00080MM",-1000,0,"i,j,o",0,"U, G1, M4, N13, B2, S","1.5.1.2"]
[null,102,"R01251MM","R01251","L-Proline+NADP+-->(S)-1-Pyrroline-5-carboxylate+NADPH+H+","C00148MM + C00006MM <=> C03912MM + C00005MM + 2 C00080MM",-1000,0,"i,j,o",0,"U, G1, M4, N13, B2, S","1.5.1.2"]
[null,103,"R01253MM","R01253","L-Proline+FAD-->(S)-1-Pyrroline-5-carboxylate+FADH2","C00148MM + C00016MM <=> C03912MM + C01352MM",null,1000,"i,j,o",0,"U, G1, G2, M4, B2, S, T","1.5.99.8"]
[null,104,"R01278MM","R01278","Palmitoyl-CoA+NADP+-->trans-Hexadec-2-enoyl-CoA+NADPH+H+","C00154MM + C00006MM <=> C05272MM + C00005MM + C00080MM",-1000,0,"i,j",0,"U, G1, G2, P, M9, B1, S, T","1.3.1.38"]
[null,105,"R01279MM","R01279","Palmitoyl-CoA+FAD-->trans-Hexadec-2-enoyl-CoA+FADH2","C00154MM + C00016MM + C00080MM <=> C05272MM + C01352MM",0,1000,"i,j",0,"U, G2, P, M7, S, T / U, G2, M16, S, T","1.3.99.13/1.3.99.3"]
[null,106,"R01280MM","R01280","ATP+Hexadecanoicacid+CoA-->AMP+Palmitoyl-CoA+Pyrophosphate","C00002MM + C00249MM + C00010MM <=> C00020MM + C00154MM + C00013MM + C00080MM",-1000,1000,"n/a",null,"U, G1, B1, P ,M7, S, T","6.2.1.3"]
[null,107,"R01280Cyto","R01280","ATP+Hexadecanoicacid+CoA-->AMP+Palmitoyl-CoA+Pyrophosphate","C00002Cyto + C00249Cyto + C00010Cyto <=> C00020Cyto + C00154Cyto + C00013Cyto + C00080Cyto",-1000,1000,"n/a",{"$error":"#N/A"},"n/a","6.2.1.3"]
[null,108,"R01325MM","R01325","Citrate-->cis-Aconitate+H2O","C00158MM <=> C00417MM + C00001MM",-1000,1000,"n/a",0,"U, G2, P, M19, S, T","4.2.1.3"]
[null,109,"R01354MM","R01354","ATP+Propanoate-->Pyrophosphate+Propinoladenylate","C00002MM + C00163MM <=> C00013MM + C05983MM",0,1000,"f,h2,i","7, Part of two step reaction where overall ->","U, G2, P, M7, S, T","6.2.1.1"]
[null,110,"R01360MM","R01360","(S)-3-Hydroxy-3-methylglutaryl-CoA-->Acetyl-CoA+Acetoacetate","C00356MM <=> C00024MM + C00164MM",-1000,1000,"n/a",0,"U, G2, M8, S, T","4.1.3.4"]
[null,111,"R01361MM","R01361","(R)-3-Hydroxybutanoate+NAD+-->Acetoacetate+NADH+H+","C01089MM + C00003MM <=> C00164MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M12, S, T","1.1.1.30"]
[null,112,"R01512Cyto","R01512","ATP+3-Phospho-D-glycerate-->ADP+3-Phospho-D-glyceroylphosphate","C00002Cyto + C00197Cyto <=> C00008Cyto + C00236Cyto + C00080Cyto",-1000,1000,"n/a","Ignore 7 as part of glycolysis","n/a","2.7.2.3"]
[null,113,"R01518Cyto","R01518","2-Phospho-D-glycerate-->3-Phospho-D-glycerate","C00631Cyto <=> C00197Cyto",-1000,1000,"n/a",0,"n/a","5.4.2.1"]
[null,114,"R01624MM","R01624","Acetyl-CoA+Acyl-carrierprotein-->CoA+Acetyl-[acyl-carrierprotein]","C00024MM + C00229MM <=> C00010MM + C03939MM",-1000,1000,"n/a",0,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,115,"R01626MM","R01626","Malonyl-CoA+Acyl-carrierprotein-->CoA+Malonyl-[acyl-carrierprotein]","C00083MM + C00229MM <=> C00010MM + C01209MM",-1000,1000,"n/a",0,"U, G, M3, N10, B2, S","2.3.1.39"]
[null,116,"R01648MM","R01648","4-Aminobutanoate+2-Oxoglutarate-->Succinatesemialdehyde+L-Glutamate","C00334MM + C00026MM <=> C00232MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M7, N20, B1, S, T","2.6.1.19"]
[null,117,"R01655MM","R01655","5,10-Methenyltetrahydrofolate+H2O-->10-Formyltetrahydrofolate+H+","C00445MM + C00001MM <=> C00234MM + C00080MM",-1000,1000,"n/a",0,"U, G1, M7, B2, S, T","6.3.4.3"]
[null,118,"R01699MM","R01699","Pyruvate+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residueacetyltransferase]S-acetyldihydrolipoyllysine+CO2","C00022MM + C15972MM + C00080MM <=> C16255MM + C00011MM",0,1000,"b,h4,i",2,"U, G2, P, M23, S, T","1.2.4.1"]
[null,119,"R01700MM","R01700","2-Oxoglutarate+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residuesuccinyltransferase]S-succinyldihydrolipoyllysine+CO2","C00026MM + C15972MM + C00080MM <=> C16254MM + C00011MM",0,1000,"b,h4,i",2,"U, G2, P, M19, S, T","1.2.4.2"]
[null,120,"R01701MM","R01701","3-Methyl-2-oxobutanoicacid+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylpropanoyl)dihydrolipoyllysine+CO2","C00141MM + C15972MM + C00080MM <=> C15977MM + C00011MM",0,1000,"b,h4,i",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,121,"R01702MM","R01702","4-Methyl-2-oxopentanoate+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(3-methylbutanoyl)dihydrolipoyllysine+CO2","C00233MM + C15972MM + C00080MM <=> C15975MM + C00011MM",0,1000,"b,h4,i",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,122,"R01706MM","R01706","Hexadecanoyl-[acp]+H2O-->Acyl-carrierprotein+Hexadecanoicacid","C05764MM + C00001MM <=> C00229MM + C00249MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","2.3.1.85"]
[null,123,"R01778MM","R01778","(3S)-3-Hydroxyacyl-CoA+NAD+-->3-Oxoacyl-CoA+NADH+H+","C00640MM + C00003MM <=> C00264MM + C00004MM + C00080MM",-1000,0,"i,k,m","13, to stop production of ATP","U, G2, M19, B2, S, T","1.1.1.211"]
[null,124,"R01786Cyto","R01786","ATP+alpha-D-Glucose-->ADP+alpha-D-Glucose6-phosphate","C00002Cyto + C00267Cyto <=> C00008Cyto + C00668Cyto + 2 C00080Cyto",-1000,1000,"n/a",{"$error":"#N/A"},"n/a","2.7.1.1/2.7.1.2"]
[null,125,"R01799MM","R01799","CTP+Phosphatidate-->Pyrophosphate+CDP-diacylglycerol","C00063MM + C00416MM <=> C00013MM + C00269MM",-1000,1000,"n/a",0,"U, G2, B2, S, T","2.7.7.41","Not in brenda"]
[null,126,"R01801MM","R01801","CDP-diacylglycerol+sn-Glycerol3-phosphate-->CMP+Phosphatidylglycerophosphate","C00269MM + C00093Cyto <=> C00055MM + C03892MM + C00080MM",0,1000,"g,i,n",9,"U, G1, M1, B2, S, T","2.7.8.5"]
[null,127,"R01857MM","R01857","ATP+dGDP-->ADP+dGTP","C00002MM + C00361MM <=> C00008MM + C00286MM",0,1000,"f,i",0,"U, G1, P, M8, B2, S, T","2.7.4.6"]
[null,128,"R01858MM","R01858","dGTP+Pyruvate-->dGDP+Phosphoenolpyruvate","C00286MM + C00022MM <=> C00361MM + C00074MM + C00080MM",-1000,0,"i,k,m,n","Required to stop production of ITP via R00724 which generates ATP from R00722","M8, S, T","2.7.1.40"]
[null,129,"R01859MM","R01859","ATP+Propanoyl-CoA+HCO3--->ADP+Orthophosphate+(S)-2-Methyl-3-oxopropanoyl-CoA","C00002MM + C00100MM + C00288MM <=> C00008MM + C00009MM + C00683MM + C00080MM",0,1000,"d,f,i,l,n","7, 4","U, G2, M7, B1, S, T","6.4.1.3"]
[null,130,"R01899MM","R01899","Isocitrate+NADP+-->Oxalosuccinate+NADPH+H+","C00311MM + C00006MM <=> C05379MM + C00005MM + C00080MM",-1000,1000,"n/a","TCA cycle","U, G2, P, M10, S, T","1.1.1.42"]
[null,131,"R01900MM","R01900","Isocitrate-->cis-Aconitate+H2O","C00311MM <=> C00417MM + C00001MM",-1000,1000,"n/a",0,"U, G2, P, M19, S, T","4.2.1.3"]
[null,132,"R01923MM","R01923","Palmitoyl-CoA+L-Carnitine-->CoA+L-Palmitoylcarnitine","C00154MM + C00318MM <=> C00010MM + C02990MM",-1000,1000,"n/a",0,"U, G2, M 11, B2, S, T","2.3.1.21"]
[null,133,"R01923Cyto","R01923c","Palmitoyl-CoA+L-Carnitine-->CoA+L-Palmitoylcarnitine","C00154Cyto + C00318Cyto <=> C00010Cyto + C02990Cyto",-1000,1000,"n/a",{"$error":"#N/A"},"n/a","2.3.1.21"]
[null,134,"R01939MM","R01939","L-2-Aminoadipate+2-Oxoglutarate-->2-Oxoadipate+L-Glutamate","C00956MM + C00026MM <=> C00322MM + C00025MM",-1000,1000,"n/a",0,"U, G1, M6, B2, S, T","2.6.1.39"]
[null,135,"R01940MM","R01940","2-Oxoadipate+Lipoamide-->S-Glutaryldihydrolipoamide+CO2","C00322MM + C15972MM + C00080MM <=> C06157MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, P, M19, S, T","1.2.4.2"]
[null,136,"R01975MM","R01975","(S)-3-Hydroxybutanoyl-CoA+NAD+-->Acetoacetyl-CoA+NADH+H+","C01144MM + C00003MM <=> C00332MM + C00004MM + C00080MM",-1000,1000,"n/a","Generates Acetoacetyl-CoA and in turn ATP from R0405 - Part of Fatty acid metabolism","U, G2, M19, B2, S, T","1.1.1.211","Not in brenda- ambigous"]
[null,137,"R01978MM","R01978","(S)-3-Hydroxy-3-methylglutaryl-CoA+CoA-->Acetyl-CoA+H2O+Acetoacetyl-CoA","C00356MM + C00010MM + C00080MM <=> C00024MM + C00001MM + C00332MM",-1000,1000,"n/a","Needed to stop R00410 generating Acetoacetyl-CoA and in turn ATP from R0405","U, G2, M11, B1, S, T","2.3.3.10"]
[null,138,"R02029MM","R02029","Phosphatidylglycerophosphate+H2O-->Phosphatidylglycerol+Orthophosphate","C03892MM + C00001MM <=> C00344MM + C00009MM",0,1000,"d,i,n",4,"L","3.1.3.27"]
[null,139,"R02030MM","R02030","Phosphatidylglycerol+CDP-diacylglycerol-->Cardiolipin+CMP","C00344MM + C00269MM <=> C05980MM + C00055MM + C00080MM",0,1000,"g,n",9,"U, G1, G2, P, M2, S","2.7.8.-"]
[null,140,"R02085MM","R02085","(S)-3-Hydroxy-3-methylglutaryl-CoA-->3-Methylglutaconyl-CoA+H2O","C00356MM <=> C03231MM + C00001MM",-1000,1000,"n/a",0,"U, G1, M4, B1, S, T","4.2.1.18"]
[null,141,"R02093MM","R02093","ATP+dTDP-->ADP+dTTP","C00002MM + C00363MM <=> C00008MM + C00459MM",-1000,1000,"n/a",0,"U, G1, P, M8, B2, T , S","2.7.4.6"]
[null,142,"R02161MM","R02161","COMPLEX_III_Ubiquinol+2Ferricytochromec-->Ubiquinone+2Ferrocytochromec"," C00390MM + 2 C00125MM + 2 C00080MM <=> C00399MM + 2 C00126MM + 4 C00080Cyto",-1000,1000,"n/a","Is complex III","L, U, G2, B2, S, T","1.10.2.2"]
[null,143,"R02163MM","R02163","COMPLEX_I_Ubiquinone+NADH-->Ubiquinol+NAD+4H+0.002O2.-","0.999 C00399MM + C00004MM + 4.994 C00080MM + 0.002 C00007MM <=> 0.999 C00390MM + C00003MM + 3.996 C00080Cyto + 0.002 C00704MM",-1000,1000,"n/a","Is complex I","L, U, G2, B2, S, T","1.6.5.3"]
[null,144,"R02164MM","R02164","COMPLEX_II_Ubiquinone+Succinate-->Ubiquinol+Fumarate"," C00399MM + C00042MM <=> C00390MM + C00122MM",-1000,1000,"n/a","Is complex II","L, U, G2, B2, S, T","1.3.5.1"]
[null,145,"R02199MM","R02199","L-Isoleucine+2-Oxoglutarate-->(S)-3-Methyl-2-oxopentanoicacid+L-Glutamate","C00407MM + C00026MM <=> C00671MM + C00025MM",-1000,1000,"n/a",0,"U, G2, M12, S, T","2.6.1.42"]
[null,146,"R02241MM","R02241","Phosphatidate+CoA-->1-Acyl-sn-glycerol3-phosphate+Palmitoyl-CoA","C00416MM + C00010MM <=> C00681MM + C00154MM",-1000,1000,"n/a",0,"G1, M1, N8, B1, S, T","2.3.1.51"]
[null,147,"R02313MM","R02313","N6-(L-1,3-Dicarboxypropyl)-L-lysine+NAD++H2O-->L-Glutamate+L-2-Aminoadipate6-semialdehyde+NADH+H+","C00449MM + C00003MM + C00001MM <=> C00025MM + C04076MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G1, M4, B1, B2, S","1.5.1.9"]
[null,148,"R02326MM","R02326","ATP+dCDP-->ADP+dCTP","C00002MM + C00705MM <=> C00008MM + C00458MM",-1000,1000,"n/a",0,"U, G1, P, M2, B2, S, T","2.7.4.6","Not in brenda"]
[null,149,"R02487MM","R02487","Glutaryl-CoA+FAD-->FADH2+Crotonoyl-CoA+CO2","C00527MM + C00016MM + 2 C00080MM <=> C01352MM + C00877MM + C00011MM",0,1000,"b,i,n",2,"U, G2, P, M5, B1, S, T","1.3.99.7"]
[null,150,"R02529MM","R02529","Aminoacetone+H2O+Oxygen-->Methylglyoxal+NH3+H2O2","C01888MM + C00001MM + C00007MM + C00080MM <=> C00546MM + C00014MM + C00027MM",-1000,1000,"n/a",null,"U, G1, B1, M7, N24, S, T","1.4.3.4"]
[null,151,"R02569MM","R02569","Acetyl-CoA+EnzymeN6-(dihydrolipoyl)lysine-->CoA+[Dihydrolipoyllysine-residueacetyltransferase]S-acetyldihydrolipoyllysine","C00024MM + C15973MM <=> C00010MM + C16255MM",-1000,1000,"n/a",0,"U, G2, P, M13, B1, S, T","2.3.1.12"]
[null,152,"R02570MM","R02570","Succinyl-CoA+EnzymeN6-(dihydrolipoyl)lysine-->CoA+[Dihydrolipoyllysine-residuesuccinyltransferase]S-succinyldihydrolipoyllysine","C00091MM + C15973MM <=> C00010MM + C16254MM",-1000,1000,"n/a",0,"U, G2, P, M18, B1, S, T","2.3.1.61"]
[null,153,"R02571MM","R02571","Glutaryl-CoA+Dihydrolipoamide-->CoA+S-Glutaryldihydrolipoamide","C00527MM + C15973MM <=> C00010MM + C06157MM",-1000,1000,"n/a",0,"U, G2, P, M18, B1, S, T","2.3.1.61"]
[null,154,"R02660MM","R02660","22-Methylpropanoyl-CoA+Oxygen-->22-Methylprop-2-enoyl-CoA+2H2O","2 C00630MM + C00007MM <=> 2 C03460MM + 2 C00001MM",0,1000,"a,h1","1,12","U, G2, M12, S, T","1.3.99.2"]
[null,155,"R02661MM","R02661","2-Methylpropanoyl-CoA+FAD-->2-Methylprop-2-enoyl-CoA+FADH2","C00630MM + C00016MM + C00080MM <=> C03460MM + C01352MM",-1000,1000,"n/a",0,"U, G2, M16, S, T","1.3.99.3"]
[null,156,"R02662MM","R02662","2-Methylpropanoyl-CoA+EnzymeN6-(dihydrolipoyl)lysine-->CoA+[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylpropanoyl)dihydrolipoyllysine","C00630MM + C15973MM <=> C00010MM + C15977MM",-1000,1000,"n/a",0,"U, G1, G2, M9, B1, S, T","2.3.1.168"]
[null,157,"R02685MM","R02685","(3S)-3-Hydroxyacyl-CoA-->trans-2,3-Dehydroacyl-CoA+H2O","C00640MM <=> C00658MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,158,"R02740Cyto","R02740","alpha-D-Glucose6-phosphate-->beta-D-Fructose6-phosphate","C00668Cyto <=> C05345Cyto",-1000,1000,"n/a",0,"n/a","5.3.1.9"]
[null,159,"R02765MM","R02765","(R)-2-Methyl-3-oxopropanoyl-CoA-->(S)-2-Methyl-3-oxopropanoyl-CoA","C01213MM <=> C00683MM",-1000,1000,"n/a",0,"U, G1, M6, B1, S","5.1.99.1"]
[null,160,"R03026MM","R03026","(S)-3-Hydroxybutanoyl-CoA-->Crotonoyl-CoA+H2O","C01144MM <=> C00877MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,161,"R03102MM","R03102","L-2-Aminoadipate6-semialdehyde+NAD++H2O-->L-2-Aminoadipate+NADH+H+","C04076MM + C00003MM + C00001MM <=> C00956MM + C00004MM + 2 C00080MM",0,1000,"h4,i,n","13, kegg","G1, M4, B1, L, S, T","1.2.1.31"]
[null,162,"R03103MM","R03103","L-2-Aminoadipate6-semialdehyde+NADP++H2O-->L-2-Aminoadipate+NADPH+H+","C04076MM + C00006MM + C00001MM <=> C00956MM + C00005MM + 2 C00080MM",0,1000,"h4,i,n","13, kegg","G1, M4, B1, L, S, T","1.2.1.31"]
[null,163,"R03105MM","R03105","Mercaptopyruvate+Sulfite-->Thiosulfate+Pyruvate","C00957MM + C00094MM <=> C00320MM + C00022MM",0,1000,"h3,i,n,o",0,"U, G2, M9, B2, S, T","2.8.1.2"]
[null,164,"R03165Cyto","R03165","Hydroxymethylbilane-->UroporphyrinogenIII+H2O","C01024Cyto <=> C01051Cyto + C00001Cyto",-1000,1000,"n/a",null,"n/a","4.2.1.75"]
[null,165,"R03170MM","R03170","2(S)-2-Methylbutanoyl-CoA+Oxygen-->22-Methylbut-2-enoyl-CoA+2H2O","2 C15980MM + C00007MM <=> 2 C03345MM + 2 C00001MM",0,1000,"a,h1","1,12","U, G2, M12, S, T","1.3.99.2"]
[null,166,"R03172MM","R03172","(S)-2-Methylbutanoyl-CoA+FAD-->2-Methylbut-2-enoyl-CoA+FADH2","C15980MM + C00016MM + C00080MM <=> C03345MM + C01352MM",-1000,1000,"n/a",0,"U, G2, M16, S, T","1.3.99.3"]
[null,167,"R03174MM","R03174","(S)-2-Methylbutanoyl-CoA+EnzymeN6-(dihydrolipoyl)lysine-->CoA+[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylbutanoyl)dihydrolipoyllysine","C15980MM + C15973MM <=> C00010MM + C15979MM",-1000,1000,"n/a",0,"U, G2, M9, B1, S, T","2.3.1.168","No enzymatic step"]
[null,168,"R03197Cyto","R03197","UroporphyrinogenIII-->CoproporphyrinogenIII+4CO2","C01051Cyto + 4 C00080Cyto <=> C03263Cyto + 4 C00011Cyto",-1000,1000,"n/a",null,"n/a","4.1.1.37"]
[null,169,"R03220Cyto","R03220","CoproporphyrinogenIII+Oxygen-->ProtoporphyrinogenIX+2CO2+2H2O","C03263Cyto + C00007Cyto + 2 C00080Cyto <=> C01079Cyto + 2 C00011Cyto + 2 C00001Cyto",-1000,1000,"n/a",null,"n/a","1.3.3.3"]
[null,170,"R03222MM","R03222","2ProtoporphyrinogenIX+3Oxygen-->2Protoporphyrin+6H2O","C01079Cyto + 3 C00007MM <=> C02191MM + 3 C00027MM",0,1000,"a,i,n",1,"U, G2, P, M5, B2, S","1.3.3.4"]
[null,171,"R03270MM","R03270","2-(alpha-Hydroxyethyl)thiaminediphosphate+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residueacetyltransferase]S-acetyldihydrolipoyllysine+Thiamindiphosphate","C05125MM + C15972MM <=> C16255MM + C00068MM",-1000,1000,"n/a",0,"U, G2, P, M23, S, T","1.2.4.1"]
[null,172,"R03313MM","R03313","L-Glutamate5-semialdehyde+Orthophosphate+NADP+-->L-Glutamyl5-phosphate+NADPH+H+","C01165MM + C00009MM + C00006MM <=> C03287MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M6, B1, S, T","1.2.1.41"]
[null,173,"R03314MM","R03314","L-Glutamate5-semialdehyde-->(S)-1-Pyrroline-5-carboxylate+H2O","C01165MM <=> C03912MM + C00001MM + C00080MM",-1000,1000,"n/a","13, used to stop loop R00245 and R00708","Non enzymatic step","spontaneous"]
[null,174,"R03316MM","R03316","3-Carboxy-1-hydroxypropyl-ThPP+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residuesuccinyltransferase]S-succinyldihydrolipoyllysine+Thiamindiphosphate","C05381MM + C15972MM <=> C16254MM + C00068MM",-1000,1000,"n/a",0,"U, G2, P, M19, S, T","1.2.4.2"]
[null,175,"R03381MM","R03381","(S)-Methylmalonatesemialdehyde+CoA+NAD+-->(R)-2-Methyl-3-oxopropanoyl-CoA+NADH+H+","C06002MM + C00010MM + C00003MM <=> C01213MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G1, M11, B2, S, T","1.2.1.18"]
[null,176,"R03758MM","R03758","Aminoacetone+CO2<=>L-2-Amino-3-oxobutanoicacid","C01888MM + C00011MM <=> C03508MM + C00080MM",-1000,0,"b,n",null,"Non enzymatic step","spontaneous"]
[null,177,"R03776MM","R03776","Octanoyl-CoA+NADP+-->trans-Oct-2-enoyl-CoA+NADPH+H+","C01944MM + C00006MM <=> C05276MM + C00005MM + C00080MM",-1000,0,"h3,i,n",13,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,178,"R03777MM","R03777","Octanoyl-CoA+FAD-->trans-Oct-2-enoyl-CoA+FADH2","C01944MM + C00016MM + C00080MM <=> C05276MM + C01352MM",0,1000,"i,j",0,"U, G2, M16, S, T","1.3.99.3"]
[null,179,"R03778MM","R03778","Octanoyl-CoA+Acetyl-CoA-->CoA+3-Oxodecanoyl-CoA","C01944MM + C00024MM <=> C00010MM + C05265MM",-1000,1000,"n/a",0,"U, G2, M15, S, T","2.3.1.16"]
[null,180,"R03856MM","R03856","Lauroyl-CoA+NADP+-->2-trans-Dodecenoyl-CoA+NADPH+H+","C01832MM + C00006MM <=> C03221MM + C00005MM + C00080MM",-1000,0,"h3,i,n",13,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,181,"R03857MM","R03857","Lauroyl-CoA+FAD-->2-trans-Dodecenoyl-CoA+FADH2","C01832MM + C00016MM + C00080MM <=> C03221MM + C01352MM",0,1000,"i,j",0,"U, G2, P, M7, S, T / U, G2, M16, S, T","1.3.99.13/1.3.99.3"]
[null,182,"R03858MM","R03858","Lauroyl-CoA+Acetyl-CoA-->CoA+3-Oxotetradecanoyl-CoA","C01832MM + C00024MM <=> C00010MM + C05261MM",-1000,1000,"n/a",0,"U, G2, M14, B1, S, T","2.3.1.16"]
[null,183,"R03989MM","R03989","Tetradecanoyl-CoA+NADP+-->trans-Tetradec-2-enoyl-CoA+NADPH+H+","C02593MM + C00006MM <=> C05273MM + C00005MM + C00080MM",-1000,0,"h3,i,n",13,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,184,"R03990MM","R03990","Tetradecanoyl-CoA+FAD-->trans-Tetradec-2-enoyl-CoA+FADH2","C02593MM + C00016MM + C00080MM <=> C05273MM + C01352MM",0,1000,"i,j",0,"U, G2, P, M7, S, T / U, G2, M16, S, T","1.3.99.13/1.3.99.3"]
[null,185,"R03991MM","R03991","Tetradecanoyl-CoA+Acetyl-CoA-->CoA+3-Oxopalmitoyl-CoA","C02593MM + C00024MM <=> C00010MM + C05259MM",-1000,1000,"n/a",0,"U, G2, M14, B1, S, T","2.3.1.16"]
[null,186,"R04095MM","R04095","3-Methylbutanoyl-CoA+FAD-->3-Methylcrotonyl-CoA+FADH2","C02939MM + C00016MM + C00080MM <=> C03069MM + C01352MM",-1000,1000,"n/a",0,"U, G2, M14, S, T","1.3.99.10"]
[null,187,"R04097MM","R04097","3-Methylbutanoyl-CoA+EnzymeN6-(dihydrolipoyl)lysine-->CoA+[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(3-methylbutanoyl)dihydrolipoyllysine","C02939MM + C15973MM <=> C00010MM + C15975MM",-1000,1000,"n/a",0,"U, G2, M9, B1, S, T","2.3.1.168"]
[null,188,"R04138MM","R04138","ATP+3-Methylcrotonyl-CoA+HCO3--->ADP+Orthophosphate+3-Methylglutaconyl-CoA","C00002MM + C03069MM + C00288MM <=> C00008MM + C00009MM + C03231MM + C00080MM",0,1000,"d,f,i,n","7,4","U, G2, M9, B2, S, T","6.4.1.4"]
[null,189,"R04170MM","R04170","(S)-3-Hydroxydodecanoyl-CoA-->2-trans-Dodecenoyl-CoA+H2O","C05262MM <=> C03221MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,190,"R04203MM","R04203","(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA+NAD+-->2-Methylacetoacetyl-CoA+NADH+H+","C04405MM + C00003MM <=> C03344MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M15, B2, S, T","1.1.1.35"]
[null,191,"R04204MM","R04204","(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA-->2-Methylbut-2-enoyl-CoA+H2O","C04405MM <=> C03345MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,192,"R04224MM","R04224","2-Methylprop-2-enoyl-CoA+H2O-->(S)-3-Hydroxyisobutyryl-CoA","C03460MM + C00001MM <=> C06000MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,193,"R04225MM","R04225","(S)-3-Methyl-2-oxopentanoicacid+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylbutanoyl)dihydrolipoyllysine+CO2","C00671MM + C15972MM + C00080MM <=> C15979MM + C00011MM",0,1000,"b,h4,i",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,194,"R04355MM","R04355","Acetyl-[acyl-carrierprotein]+Malonyl-[acyl-carrierprotein]-->Acetoacetyl-[acp]+CO2+Acyl-carrierprotein","C03939MM + C01209MM + C00080MM <=> C05744MM + C00011MM + C00229MM",0,1000,"b,i,n",2,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,195,"R04428MM","R04428","(3R)-3-Hydroxybutanoyl-[acyl-carrierprotein]-->But-2-enoyl-[acyl-carrierprotein]+H2O","C04618MM <=> C04246MM + C00001MM",-1000,1000,"n/a",0,"M3, N11, S","2.3.1.85"]
[null,196,"R04430MM","R04430","Butyryl-[acp]+NADP+-->But-2-enoyl-[acyl-carrierprotein]+NADPH+H+","C05745MM + C00006MM <=> C04246MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, B1, S","1.3.1.10"]
[null,197,"R04433MM","R04433MM","Ubiquinone+FADH2-->Ubiquinol+FAD+","C00399MM + C01352MM <=> C00390MM + C00016MM + C00080MM",-1000,1000,"n/a",null,"U, G2, B1, P, M16, N39, T, S, L","1.5.5.1"]
[null,198,"R04533MM","R04533","(3R)-3-Hydroxybutanoyl-[acyl-carrierprotein]+NADP+-->Acetoacetyl-[acp]+NADPH+H+","C04618MM + C00006MM <=> C05744MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,199,"R04534MM","R04534","(3R)-3-Hydroxydecanoyl-[acyl-carrierprotein]+NADP+-->3-Oxodecanoyl-[acp]+NADPH","C04619MM + C00006MM <=> C05753MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,200,"R04535MM","R04535","(3R)-3-Hydroxydecanoyl-[acyl-carrierprotein]-->trans-Dec-2-enoyl-[acp]+H2O","C04619MM <=> C05754MM + C00001MM",-1000,1000,"n/a",null,"M3, N11, S","2.3.1.85"]
[null,201,"R04536MM","R04536","(3R)-3-Hydroxyoctanoyl-[acyl-carrierprotein]+NADP+-->3-Oxooctanoyl-[acp]+NADPH+H+","C04620MM + C00006MM <=> C05750MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,202,"R04537MM","R04537","(3R)-3-Hydroxyoctanoyl-[acyl-carrierprotein]-->trans-Oct-2-enoyl-[acp]+H2O","C04620MM <=> C05751MM + C00001MM",-1000,1000,"n/a",0,"M3, N11, S","2.3.1.85"]
[null,203,"R04543MM","R04543","(3R)-3-Hydroxypalmitoyl-[acyl-carrierprotein]+NADP+-->3-Oxohexadecanoyl-[acp]+NADPH+H+","C04633MM + C00006MM <=> C05762MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,204,"R04544MM","R04544","(3R)-3-Hydroxypalmitoyl-[acyl-carrierprotein]-->trans-Hexadec-2-enoyl-[acp]+H2O","C04633MM <=> C05763MM + C00001MM",-1000,1000,"n/a",null,"M3, N11, S","2.3.1.85"]
[null,205,"R04566MM","R04566","(3R)-3-Hydroxytetradecanoyl-[acyl-carrierprotein]+NADP+-->3-Oxotetradecanoyl-[acp]+NADPH+H+","C04688MM + C00006MM <=> C05759MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,206,"R04568MM","R04568","(3R)-3-Hydroxytetradecanoyl-[acyl-carrierprotein]-->trans-Tetradec-2-enoyl-[acp]+H2O","C04688MM <=> C05760MM + C00001MM",-1000,1000,"n/a",null,"M3, N11, S","2.3.1.85"]
[null,207,"R04725MM","R04725","Dodecanoyl-[acyl-carrierprotein]+NADP+-->trans-Dodec-2-enoyl-[acp]+NADPH+H+","C05223MM + C00006MM <=> C05758MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.3.1.10 & 2.3.1.85"]
[null,208,"R04726MM","R04726","Dodecanoyl-[acyl-carrierprotein]+Malonyl-[acyl-carrierprotein]-->3-Oxotetradecanoyl-[acp]+CO2+Acyl-carrierprotein","C05223MM + C01209MM + C00080MM <=> C05759MM + C00011MM + C00229MM",0,1000,"b,n",null,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,209,"R04737MM","R04737","(S)-3-Hydroxyhexadecanoyl-CoA+NAD+-->3-Oxopalmitoyl-CoA+NADH+H+","C05258MM + C00003MM <=> C05259MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,210,"R04738MM","R04738","(S)-3-Hydroxyhexadecanoyl-CoA-->trans-Hexadec-2-enoyl-CoA+H2O","C05258MM <=> C05272MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,211,"R04739MM","R04739","(S)-3-Hydroxytetradecanoyl-CoA+NAD+-->3-Oxotetradecanoyl-CoA+NADH","C05260MM + C00003MM <=> C05261MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,212,"R04740MM","R04740","(S)-3-Hydroxytetradecanoyl-CoA-->trans-Tetradec-2-enoyl-CoA+H2O","C05260MM <=> C05273MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,213,"R04741MM","R04741","(S)-3-Hydroxydodecanoyl-CoA+NAD+-->3-Oxododecanoyl-CoA+NADH+H+","C05262MM + C00003MM <=> C05263MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,214,"R04742MM","R04742","Decanoyl-CoA+Acetyl-CoA-->CoA+3-Oxododecanoyl-CoA","C05274MM + C00024MM <=> C00010MM + C05263MM",-1000,1000,"n/a",0,"U, G2, M15, S, T","2.3.1.16"]
[null,215,"R04743MM","R04743","(S)-Hydroxydecanoyl-CoA+NAD+-->3-Oxodecanoyl-CoA+NADH+H+","C05264MM + C00003MM <=> C05265MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,216,"R04744MM","R04744","(S)-Hydroxydecanoyl-CoA-->trans-Dec-2-enoyl-CoA+H2O","C05264MM <=> C05275MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,217,"R04745MM","R04745","(S)-Hydroxyoctanoyl-CoA+NAD+-->3-Oxooctanoyl-CoA+NADH+H+","C05266MM + C00003MM <=> C05267MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,218,"R04746MM","R04746","(S)-Hydroxyoctanoyl-CoA-->trans-Oct-2-enoyl-CoA+H2O","C05266MM <=> C05276MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17"]
[null,219,"R04747MM","R04747","Hexanoyl-CoA+Acetyl-CoA-->CoA+3-Oxooctanoyl-CoA","C05270MM + C00024MM <=> C00010MM + C05267MM",-1000,1000,"n/a",0,"U, G2, M15, S, T","2.3.1.16"]
[null,220,"R04748MM","R04748","(S)-Hydroxyhexanoyl-CoA+NAD+-->3-Oxohexanoyl-CoA+NADH+H+","C05268MM + C00003MM <=> C05269MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M19, B2, S, T","1.1.1.211"]
[null,221,"R04749MM","R04749","(S)-Hydroxyhexanoyl-CoA-->trans-Hex-2-enoyl-CoA+H2O","C05268MM <=> C05271MM + C00001MM",-1000,1000,"n/a",0,"U, G2, M18, B2, S, T","4.2.1.17","Ambigous EC- no brenda"]
[null,222,"R04751MM","R04751","Hexanoyl-CoA+FAD-->trans-Hex-2-enoyl-CoA+FADH2","C05270MM + C00016MM + C00080MM <=> C05271MM + C01352MM",0,1000,"i,j",0,"U, G2, M16, S, T","1.3.99.3"]
[null,223,"R04753MM","R04753","Decanoyl-CoA+NADP+-->trans-Dec-2-enoyl-CoA+NADPH+H+","C05274MM + C00006MM <=> C05275MM + C00005MM + C00080MM",-1000,0,"h3,i,n",13,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,224,"R04754MM","R04754","Decanoyl-CoA+FAD-->trans-Dec-2-enoyl-CoA+FADH2","C05274MM + C00016MM + C00080MM <=> C05275MM + C01352MM",0,1000,"i,j",0,"U, G1, G2, M16, S, T","1.3.99.3"]
[null,225,"R04779Cyto","R04779","ATP+beta-D-Fructose6-phosphate-->ADP+beta-D-Fructose1,6-bisphosphate","C00002Cyto + C05345Cyto <=> C00008Cyto + C05378Cyto + 2 C00080Cyto",0,1000,"f,i,n",7,"n/a","2.7.1.11"]
[null,226,"R04952MM","R04952","Butyryl-[acp]+Malonyl-[acyl-carrierprotein]-->3-Oxohexanoyl-[acp]+CO2+Acyl-carrierprotein","C05745MM + C01209MM + C00080MM <=> C05746MM + C00011MM + C00229MM",0,1000,"b,n",2,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,227,"R04953MM","R04953","(R)-3-Hydroxyhexanoyl-[acp]+NADP+-->3-Oxohexanoyl-[acp]+NADPH+H+","C05747MM + C00006MM <=> C05746MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,228,"R04954MM","R04954","(R)-3-Hydroxyhexanoyl-[acp]-->trans-Hex-2-enoyl-[acp]+H2O","C05747MM <=> C05748MM + C00001MM",-1000,1000,"n/a",0,"M3, N11, S","2.3.1.85"]
[null,229,"R04956MM","R04956","Hexanoyl-[acp]+NADP+-->trans-Hex-2-enoyl-[acp]+NADPH+H+","C05749MM + C00006MM <=> C05748MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","2.3.1.85"]
[null,230,"R04957MM","R04957","Hexanoyl-[acp]+Malonyl-[acyl-carrierprotein]-->3-Oxooctanoyl-[acp]+CO2+Acyl-carrierprotein","C05749MM + C01209MM + C00080MM <=> C05750MM + C00011MM + C00229MM",0,1000,"b,n",2,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,231,"R04959MM","R04959","Octanoyl-[acp]+NADP+-->trans-Oct-2-enoyl-[acp]+NADPH+H+","C05752MM + C00006MM <=> C05751MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"M3, N11, S","2.3.1.85"]
[null,232,"R04960MM","R04960MM","Octanoyl-[acp]+Malonyl-[acyl-carrierprotein]-->3-Oxodecanoyl-[acp]+CO2+Acyl-carrierprotein","C05752MM + C01209MM + C00080MM <=> C05753MM + C00011MM + C00229MM",0,1000,"b,n",null,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,233,"R04962MM","R04962MM","Decanoyl-[acp]+NADP+-->trans-Dec-2-enoyl-[acp]+NADPH+H+","C05755MM + C00006MM <=> C05754MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.3.1.10 / 2.3.1.85"]
[null,234,"R04963MM","R04963MM","Decanoyl-[acp]+Malonyl-[acyl-carrierprotein]-->3-Oxododecanoyl-[acp]+CO2+Acyl-carrierprotein","C05755MM + C01209MM + C00080MM <=> C05756MM + C00011MM + C00229MM",0,1000,"b,n",null,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,235,"R04964MM","R04964MM","(R)-3-Hydroxydodecanoyl-[acp]+NADP+-->3-Oxododecanoyl-[acp]+NADPH+H+","C05757MM + C00006MM <=> C05756MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.1.1.100 / 2.3.1.85"]
[null,236,"R04965MM","R04965MM","(R)-3-Hydroxydodecanoyl-[acp]-->trans-Dodec-2-enoyl-[acp]+H2O","C05757MM <=> C05758MM + C00001MM",-1000,1000,"n/a",null,"M3, N11, S","2.3.1.85"]
[null,237,"R04967MM","R04967MM","Tetradecanoyl-[acp]+NADP+-->trans-Tetradec-2-enoyl-[acp]+NADPH+H+","C05761MM + C00006MM <=> C05760MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.3.1.10 / 2.3.1.85"]
[null,238,"R04968MM","R04968MM","Tetradecanoyl-[acp]+Malonyl-[acyl-carrierprotein]-->3-Oxohexadecanoyl-[acp]+CO2+Acyl-carrierprotein","C05761MM + C01209MM + C00080MM <=> C05762MM + C00011MM + C00229MM",0,1000,"b,n",null,"U, G1, M4, B1, S, T","2.3.1.41"]
[null,239,"R04970MM","R04970MM","Hexadecanoyl-[acp]+NADP+-->trans-Hexadec-2-enoyl-[acp]+NADPH+H+","C05764MM + C00006MM <=> C05763MM + C00005MM + C00080MM",-1000,1000,"n/a",null,"M3, N11, S","1.3.1.10 / 2.3.1.85"]
[null,240,"R05064MM","R05064","(S)-3-Hydroxyisobutyryl-CoA+H2O-->CoA+(S)-3-Hydroxyisobutyrate","C06000MM + C00001MM <=> C00010MM + C06001MM + C00080MM",-1000,1000,"n/a",0,"U, G1, P, M11, B1, S, T","3.1.2.4"]
[null,241,"R05066MM","R05066","(S)-3-Hydroxyisobutyrate+NAD+-->(S)-Methylmalonatesemialdehyde+NADH+H+","C06001MM + C00003MM <=> C06002MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, M15, B2, S, T","1.1.1.35"]
[null,242,"R06985MM","R06985","trans-Hex-2-enoyl-CoA+NADPH+H+-->Hexanoyl-CoA+NADP+","C05271MM + C00005MM + C00080MM <=> C05270MM + C00006MM",0,1000,"h3,i,n",13,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,243,"R07162MM","R07162","Acyl-CoA+NADP+-->trans-2,3-Dehydroacyl-CoA+NADPH+H+","C00040MM + C00006MM <=> C00658MM + C00005MM + C00080MM",-1000,1000,"n/a",0,"U, G2, P, M9, B1, S, T","1.3.1.38"]
[null,244,"R07390MM","R07390","2Phosphatidylglycerol-->Cardiolipin+Glycerol","2 C00344MM <=> C05980MM + C00116MM",-1000,1000,"n",0,"U, G2, P, M2, S","2.7.8.-"]
[null,245,"R07599MM","R07599","3-Methyl-2-oxobutanoicacid+Thiamindiphosphate-->2-Methyl-1-hydroxypropyl-ThPP+CO2","C00141MM + C00068MM + C00080MM <=> C15976MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,246,"R07600MM","R07600","2-Methyl-1-hydroxypropyl-ThPP+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylpropanoyl)dihydrolipoyllysine+Thiamindiphosphate","C15976MM + C15972MM <=> C15977MM + C00068MM",-1000,1000,"n/a",0,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,247,"R07601MM","R07601","4-Methyl-2-oxopentanoate+Thiamindiphosphate-->3-Methyl-1-hydroxybutyl-ThPP+CO2","C00233MM + C00068MM + C00080MM <=> C15974MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,248,"R07602MM","R07602","3-Methyl-1-hydroxybutyl-ThPP+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(3-methylbutanoyl)dihydrolipoyllysine+Thiamindiphosphate","C15974MM + C15972MM <=> C15975MM + C00068MM",-1000,1000,"n/a",0,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,249,"R07603MM","R07603","(S)-3-Methyl-2-oxopentanoicacid+Thiamindiphosphate-->2-Methyl-1-hydroxybutyl-ThPP+CO2","C00671MM + C00068MM + C00080MM <=> C15978MM + C00011MM",0,1000,"b,h4,i,n",2,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,250,"R07604MM","R07604","2-Methyl-1-hydroxybutyl-ThPP+EnzymeN6-(lipoyl)lysine-->[Dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]S-(2-methylbutanoyl)dihydrolipoyllysine+Thiamindiphosphate","C15978MM + C15972MM <=> C15979MM + C00068MM",-1000,1000,"n/a",0,"U, G2, M6, B2, S, T","1.2.4.4"]
[null,251,"R07618MM","R07618","EnzymeN6-(dihydrolipoyl)lysine+NAD+-->EnzymeN6-(lipoyl)lysine+NADH+H+","C15973MM + C00003MM <=> C15972MM + C00004MM + C00080MM",-1000,1000,"n/a",0,"U, G2, P, M18, B1, S, T","1.8.1.4"]
[null,252,"R08157MM","R08157","Octanoyl-[acp]+H2O-->Acyl-carrierprotein+Octanoicacid","C05752MM + C00001MM <=> C00229MM + C06423MM = C00080MM",-1000,1000,"n/a",0,"G1, M3, S","3.1.2.-"]
[null,253,"R08657MM","R08657","sn-Glycerol","C00093Cyto + C00399MM <=> C00111Cyto + C00390MM",0,1000,"j,m","Is part of the glycerol phosphate shuttle","U, G2, M10, B2, S, T","1.1.5.3"]