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{"sheet":"Transport & Boundary Supplement","index":0,"n_rows":166,"n_cols":9,"rows_kept":166,"cut":false,"hidden":false,"merged":[]}
[]
[null,"Row","Identifier","Description","Equation","LB","UB"]
[null,1,"Transporter1","Citrate carrier - Malate for citrate","C00158Cyto + C00149MM <=> C00158MM + C00149Cyto",-1000,0]
[null,2,"Transporter2","Citrate carrier - Malate for isocitrate","C00311MM + C00149Cyto <=> C00311Cyto + C00149MM",0,1000]
[null,3,"Transporter3","Citrate carrier - PEP for citrate","C00158MM + C00074Cyto <=> C00158Cyto + C00074MM",0,1000]
[null,4,"Transporter4","Citrate carrier - PEP for isocitrate","C00311MM + C00074Cyto <=> C00311Cyto + C00074MM",0,1000]
[null,5,"Transporter5","Citrate carrier - Citrate for Isocitrate","C00158MM + C00311Cyto <=> C00158Cyto + C00311MM",-1000,1000]
[null,6,"Transporter6","Phosphate carrier - Phosphate and H+ together","C00009MM + C00080MM <=> C00009Cyto + C00080Cyto",-1000,1000]
[null,7,"Transporter7","ADP/ATP carrier - ADP for ATP","C00008MM + C00002Cyto <=> C00008Cyto + C00002MM + C00080Cyto",-1000,1000]
[null,8,"Transporter8","UCP carrier - H+","C00080MM <=> C00080Cyto",-1000,0]
[null,9,"Transporter9","Dicarboxylate carrier - Malate for phosphate","C00149MM + C00009Cyto <=> C00149Cyto + C00009MM",0,1000]
[null,10,"Transporter10","Dicarboxylate carrier - Succinate for phosphate","C00042MM + C00009Cyto <=> C00042Cyto + C00009MM",-1000,1000]
[null,11,"Transporter11","Dicarboxylate carrier - Malate for sulphite","C00149MM + C00094Cyto <=> C00149Cyto + C00094MM",0,1000]
[null,12,"Transporter12","Dicarboxylate carrier - Malate for sulfate","C00149MM + C00059Cyto <=> C00149Cyto + C00059MM",0,1000]
[null,13,"Transporter13","Dicarboxylate carrier - Malate for thiosulfate","C00149MM + C00320Cyto <=> C00149Cyto + C00320MM",0,1000]
[null,14,"Transporter14","Dicarboxylate carrier - Succinate for sulphite","C00042MM + C00094Cyto <=> C00042Cyto + C00094MM",-1000,0]
[null,15,"Transporter15","Dicarboxylate carrier - Succinate for sulfate","C00042MM + C00059Cyto <=> C00042Cyto + C00059MM",-1000,0]
[null,16,"Transporter16","Dicarboxylate carrier - Succinate for thiosulfate","C00042MM + C00320Cyto <=> C00042Cyto + C00320MM",-1000,0]
[null,17,"Transporter17","Oxoglutarate carrier - Oxoglutarate for malate","C00026Cyto + C00149MM <=> C00026MM + C00149Cyto",-1000,0]
[null,18,"Transporter18","Aspartate/glutamate carrier - Glutamate and H+ for aspartate","C00049MM + C00025Cyto + C00080Cyto <=> C00049Cyto + C00025MM + C00080MM",-1000,1000]
[null,19,"Transporter19","Ornithine carrier - Ornithine for citrulline and H+","C00077MM + C00327Cyto + C00080Cyto <=> C00077Cyto + C00327MM + C00080MM",-1000,1000]
[null,20,"Transporter20","Ornithine carrier - Lysine for citrulline and H+","C00047MM + C00327Cyto + C00080Cyto <=> C00047Cyto + C00327MM + C00080MM",-1000,0]
[null,21,"Transporter21","Ornithine carrier - Arginine for citrulline and H+","C00062MM + C00327Cyto + C00080Cyto <=> C00062Cyto + C00327MM + C00080MM",-1000,0]
[null,22,"Transporter22","Ornithine carrier - Ornithine for lysine and H+","C00077MM + C00047Cyto + C00080Cyto <=> C00077Cyto + C00047MM + C00080MM",0,1000]
[null,23,"Transporter23","Ornithine carrier - Ornithine for arginine and H+","C00077MM + C00062Cyto + C00080Cyto <=> C00077Cyto + C00062MM + C00080MM",0,1000]
[null,24,"Transporter24","Ornithine carrier - Lysine for arginine and H+","C00047MM + C00062Cyto + C00080Cyto <=> C00047Cyto + C00062MM + C00080MM",-1000,1000]
[null,25,"Transporter25","Ornithine carrier - L-Lysine for H+","C00047MM + C00080Cyto <=> C00047Cyto + C00080MM",-1000,0]
[null,26,"Transporter26","Ornithine carrier - L-Ornithine for H+","C00077MM + C00080Cyto <=> C00077Cyto + C00080MM",-1000,1000]
[null,27,"Transporter27","Ornithine carrier - L-Arginine for H+","C00062MM + C00080Cyto <=> C00062Cyto + C00080MM",-1000,0]
[null,28,"Transporter28","Ornithine carrier - L-Citrulline for H+","C00327MM + C00080Cyto <=> C00327Cyto + C00080MM",0,1000]
[null,29,"Transporter29","Graves disease carrier - CoA","C00010MM <=> C00010Cyto",-1000,0]
[null,30,"Transporter30","Glutamate carrier - Glutamate and H+","C00025MM + C00080MM <=> C00025Cyto + C00080Cyto",-1000,0]
[null,31,"Transporter31","deoxynucleotide carrier - dATP ","C00131MM <=> C00131Cyto",-1000,0]
[null,32,"Transporter32","deoxynucleotide carrier - dGTP","C00286MM <=> C00286Cyto",-1000,0]
[null,33,"Transporter33","deoxynucleotide carrier - dCTP","C00458MM <=> C00458Cyto",-1000,0]
[null,34,"Transporter34","deoxynucleotide carrier - dTTP","C00459MM <=> C00459Cyto",-1000,0]
[null,35,"Transporter35","deoxynucleotide carrier - dADP","C00206MM <=> C00206Cyto",-1000,0]
[null,36,"Transporter36","deoxynucleotide carrier - dGDP","C00361MM <=> C00361Cyto",-1000,0]
[null,37,"Transporter37","deoxynucleotide carrier - dCDP","C00705MM <=> C00705Cyto",-1000,0]
[null,38,"Transporter38","deoxynucleotide carrier - dTDP","C00363MM <=> C00363Cyto",-1000,0]
[null,39,"Transporter39","deoxynucleotide carrier - ADP","C00008MM <=> C00008Cyto",-1000,0]
[null,40,"Transporter40","deoxynucleotide carrier - GDP","C00035MM <=> C00035Cyto",-1000,0]
[null,41,"Transporter41","deoxynucleotide carrier - UDP","C00015MM <=> C00015Cyto",-1000,0]
[null,42,"Transporter42","deoxynucleotide carrier - CDP","C00112MM <=> C00112Cyto",-1000,0]
[null,43,"Transporter43","Slc25a19 carrier - ThPP","C00068MM <=> C00068Cyto",-1000,0]
[null,44,"Transporter44","carnitine carrier - Carnitine out, palmitoyl/acyl carnitine in ","C00318MM + C02990Cyto <=> C00318Cyto + C02990MM",0,1000]
[null,45,"Transporter45","carnitine carrier - Carnitine out","C00318MM <=> C00318Cyto",0,1000]
[null,46,"Transporter46","oxodicarboxylate carrier - Oxoadipate for oxoglutarate","C00322MM + C00026Cyto <=> C00322Cyto + C00026MM",-1000,0]
[null,47,"Transporter47","oxodicarboxylate carrier - 2-aminoadipate for oxoglutarate","C00956MM + C00026Cyto <=> C00956Cyto + C00026MM",-1000,0]
[null,48,"Transporter48","oxodicarboxylate carrier - citrate for oxoglutarate","C00158MM + C00026Cyto <=> C00158Cyto + C00026MM",-1000,0]
[null,49,"Transporter49","oxodicarboxylate carrier - oxaloacetate for oxoglutarate","C00036MM + C00026Cyto <=> C00036Cyto + C00026MM",-1000,0]
[null,50,"Transporter50","Unknown pyruvate carrier - Pyruvate","C00022MM + C00080MM <=> C00022Cyto + C00080Cyto",-1000,0]
[null,51,"Transporter51","Unknown carrier - NAD+","C00003MM <=> C00003Cyto",-1000,1000]
[null,52,"Transporter52","Diffusion - CO2","C00011MM <=> C00011Cyto",-1000,1000]
[null,53,"Transporter53","Diffusion - H2O","C00001MM <=> C00001Cyto",-1000,1000]
[null,54,"Transporter54","Diffusion - Oxygen","C00007MM <=> C00007Cyto",-1000,0]
[null,55,"Transporter55","Diffusion - Glycerol","C00116MM <=> C00116Cyto",-1000,1000]
[null,56,"Transporter56","Diffusion - Ethanal","C00084MM <=> C00084Cyto",-1000,1000]
[null,57,"Transporter57","FAD carrier - FAD","C00016MM <=> C00016Cyto",-1000,1000]
[null,58,"Transporter58","Phosphatidylserine carrier - Phosphatidylserine","C02737MM <=> C02737Cyto",-1000,0]
[null,59,"Transporter59","Phosphatidylcholine carrier - Phosphatidylcholine","C00157MM <=> C00157Cyto",-1000,0]
[null,60,"Transporter60","Phosphatidylethanolamine carrier - Phosphatidylethanolamine","C00350MM + C00080MM <=> C00350Cyto",-1000,0]
[null,61,"Transporter61","Diffusion? - Propanoate","C00163MM <=> C00163Cyto",-1000,1000]
[null,62,"Transporter62","Diffusion? - Butanoic acid","C00246MM <=> C00246Cyto",-1000,1000]
[null,63,"Transporter63","MitoFerrin carrier - Fe2+","C14818MM <=> C14818Cyto",-1000,1000]
[null,64,"Transporter64","Unknown amino acid carrier - L-Asparagine","C00152MM <=> C00152Cyto",-1000,1000]
[null,65,"Transporter65","Unknown amino acid carrier - L-Cysteine","C00097MM <=> C00097Cyto",-1000,1000]
[null,66,"Transporter66","Unknown amino acid carrier - L-Glutamine","C00064MM <=> C00064Cyto",-1000,1000]
[null,67,"Transporter67","Unknown amino acid carrier - L-Proline","C00148MM <=> C00148Cyto",-1000,1000]
[null,68,"Transporter68","Unknown amino acid carrier - L-Tyrosine","C00082MM <=> C00082Cyto",-1000,1000]
[null,69,"Transporter69","Unknown amino acid carrier - L-Histidine","C00135MM <=> C00135Cyto",-1000,1000]
[null,70,"Transporter70","Unknown amino acid carrier - L-Methionine","C00073MM <=> C00073Cyto",-1000,1000]
[null,71,"Transporter71","Unknown amino acid carrier - L-Phenylalanine","C00079MM <=> C00079Cyto",-1000,1000]
[null,72,"Transporter72","Unknown amino acid carrier - L-Tryptophan","C00078MM <=> C00078Cyto",-1000,1000]
[null,73,"Transporter73","Unknown amino acid carrier - Glycine","C00037MM <=> C00037Cyto",-1000,1000]
[null,74,"Transporter74","Unknown amino acid carrier - L-Isoleucine","C00407MM <=> C00407Cyto",-1000,1000]
[null,75,"Transporter75","Unknown amino acid carrier - L-Leucine","C00123MM <=> C00123Cyto",-1000,1000]
[null,76,"Transporter76","Unknown amino acid carrier - L-Valine","C00183MM <=> C00183Cyto",-1000,1000]
[null,77,"Transporter77","Unknown carrier - Glutathione","C00051MM <=> C00051Cyto",-1000,1000]
[null,78,"Transporter78","Unknown carrier - 5-Aminolevulinate","C00430MM + C00080MM <=> C00430Cyto",-1000,1000]
[null,79,"Transporter79","Unknown carrier - (R)-3-Hydroxybutanoate","C01089MM <=> C01089Cyto",-1000,1000]
[null,80,"Transporter80","Unknown carrier - Urea","C00086MM <=> C00086Cyto",0,1000]
[null,81,"Transporter81","Unknown carrier - Fumarate","C00122MM <=> C00122Cyto",0,1000]
[null,82,"Transporter82","Unknown carrier - Acetoacetate","C00164MM <=> C00164Cyto",-1000,1000]
[null,83,"Transporter83","Biomass","C00000MM <=> C00000Cyto",0,1000]
[null,84,"Transporter84","Unknown carrier - HCO3-","C00288MM <=> C00288Cyto",-1000,1000]
[null,85,"Transporter85","Diffusion? - NH3","C00014MM <=> C00014Cyto",-1000,0]
[null,86,"Transporter86","Putrescine","C00134MM <=> C00134Cyto",-1000,1000]
[null,87,"Transporter87","L-Alanine","C00041MM <=> C00041Cyto",-1000,1000]
[null,88,"Transporter88","L-Serine","C00065MM <=> C00065Cyto",-1000,1000]
[null,89,"Transporter89","L-Threonine","C00188MM <=> C00188Cyto",-1000,1000]
[]
[null,"Row","Identifier","Description","Equation","LB","UB","Species/Tissue","PubMed ID"]
[null,1,"Boundary1","CO2","C00011_b <=> C00011Cyto",-1000,1000]
[null,2,"Boundary2","FAD","C00016_b <=> C00016Cyto",-1000,1000]
[null,3,"Boundary3","Oxygen","C00007_b <=> C00007Cyto",-1000,19.8,"Rat heart",9486263]
[null,4,"Boundary4","Glutathione","C00051_b <=> C00051Cyto",-1000,1000]
[null,5,"Boundary5","L-Arginine","C00062_b <=> C00062Cyto",-1000,6.7999999999999996E-3,"Rat heart",690905]
[null,6,"Boundary6","L-Lysine","C00047_b <=> C00047Cyto",-1000,2.98E-2,"Rat heart",690905]
[null,7,"Boundary7","L-Glutamate","C00025_b <=> C00025Cyto",-1000,0]
[null,8,"Boundary8","L-Proline","C00148_b <=> C00148Cyto",-1000,4.4000000000000003E-3,"Rat heart",690905]
[null,9,"Boundary9","Fe2+","C14818_b <=> C14818Cyto",-1000,1000]
[null,10,"Boundary10","L-Aspartate","C00049_b <=> C00049Cyto",-1000,0.15240000000000001,"Human heart",11557236]
[null,11,"Boundary11","Glycine","C00037_b <=> C00037Cyto",-1000,8.8999999999999999E-3,"Rat heart",690905]
[null,12,"Boundary12","L-Tyrosine","C00082_b <=> C00082Cyto",-1000,1.0800000000000001E-2,"Rat heart",690905]
[null,13,"Boundary13","L-Asparagine","C00152_b <=> C00152Cyto",-1000,1000]
[null,14,"Boundary14","L-Methionine","C00073_b <=> C00073Cyto",-1000,5.0000000000000001E-3,"Rat heart",690905]
[null,15,"Boundary15","L-Phenylalanine","C00079_b <=> C00079Cyto",-1000,1.21E-2,"Rat heart",690905]
[null,16,"Boundary16","L-Tryptophan","C00078_b <=> C00078Cyto",-1000,8.0000000000000002E-3,"Rat heart",690905]
[null,17,"Boundary17","L-Histidine","C00135_b <=> C00135Cyto",-1000,9.7999999999999997E-3,"Rat heart",690905]
[null,18,"Boundary18","L-Glutamine","C00064_b <=> C00064Cyto",-1000,{"$f":"(0.14+0.02)*5","v":0.8},"Rat heart",11968138]
[null,19,"Boundary19","5-Aminolevulinate","C00430_b <=> C00430Cyto",-1000,0]
[null,20,"Boundary20","L-Cysteine","C00097_b <=> C00097Cyto",-1000,1E-3,"Rat heart",690905]
[null,21,"Boundary21","Phosphatidylcholine","C00157_b <=> C00157Cyto",-1000,1000]
[null,22,"Boundary22","Phosphatidylserine","C02737_b <=> C02737Cyto",-1000,1000]
[null,23,"Boundary23","Phosphatidylethanolamine","C00350_b <=> C00350Cyto",-1000,1000]
[null,24,"Boundary24","alpha-D-Glucose","C00267_b <=> C00267Cyto",-1000,0.9,"Human heart","UB: 1601987, 8182160"]
[null,25,"Boundary25","Glycerol","C00116_b <=> C00116Cyto",-1000,1000]
[null,26,"Boundary26","Propanoate","C00163_b <=> C00163Cyto",-1000,0]
[null,27,"Boundary27","Sulfate","C00059_b <=> C00059Cyto",-1000,1000]
[null,28,"Boundary28","Sulfite","C00094_b <=> C00094Cyto",-1000,1000]
[null,29,"Boundary29","Thiosulfate","C00320_b <=> C00320Cyto",-1000,1000]
[null,30,"Boundary30","Succinate","C00042_b <=> C00042Cyto",-1000,0]
[null,31,"Boundary31","(S)-Malate","C00149_b <=> C00149Cyto",-1000,0]
[null,32,"Boundary32","Isocitrate","C00311_b <=> C00311Cyto",-1000,0]
[null,33,"Boundary33","Citrate","C00158_b <=> C00158Cyto",-1000,0]
[null,34,"Boundary34","Butanoic acid","C00246_b <=> C00246Cyto",-1000,6.0000000000000001E-3,"Rat brain",11746406]
[null,35,"Boundary35","Oxaloacetate","C00036_b <=> C00036Cyto",-1000,0]
[null,36,"Boundary36","L-2-Aminoadipate","C00956_b <=> C00956Cyto",-1000,1000]
[null,37,"Boundary37","2-Oxoadipate","C00322_b <=> C00322Cyto",-1000,1000]
[null,38,"Boundary38","CoA","C00010_b <=> C00010Cyto",-1000,1000]
[null,39,"Boundary39","H2O","C00001_b <=> C00001Cyto",-1000,1000]
[null,40,"Boundary40","(R)-3-Hydroxybutanoate","C01089_b + C00080_b <=> C01089Cyto + C00080Cyto",0,0.7,"Lamb heart",11356176]
[null,41,"Boundary41","Urea","C00086_b <=> C00086Cyto",-1000,1000]
[null,42,"Boundary42","Orthophosphate","C00009_b <=> C00009Cyto",-1000,1000]
[null,43,"Boundary43","Thiamin diphosphate","C00068_b <=> C00068Cyto",-1000,1000]
[null,44,"Boundary44","Biomass","C00000_b <=> C00000Cyto",-1000,0]
[null,45,"Boundary45","NAD+","C00003_b <=> C00003Cyto",-1000,1000]
[null,46,"Boundary46","ADP","C00008_b <=> C00008Cyto",-1000,1000]
[null,47,"Boundary47","UDP","C00015_b <=> C00015Cyto",-1000,1000]
[null,48,"Boundary48","2-Oxoglutarate","C00026_b <=> C00026Cyto",-1000,0]
[null,49,"Boundary49","GDP","C00035_b <=> C00035Cyto",-1000,1000]
[null,50,"Boundary50","CDP","C00112_b <=> C00112Cyto",-1000,1000]
[null,51,"Boundary51","dATP","C00131_b <=> C00131Cyto",-1000,1000]
[null,52,"Boundary52","dADP","C00206_b <=> C00206Cyto",-1000,1000]
[null,53,"Boundary53","dGTP","C00286_b <=> C00286Cyto",-1000,1000]
[null,54,"Boundary54","dGDP","C00361_b <=> C00361Cyto",-1000,1000]
[null,55,"Boundary55","dTDP","C00363_b <=> C00363Cyto",-1000,1000]
[null,56,"Boundary56","dCTP","C00458_b <=> C00458Cyto",-1000,1000]
[null,57,"Boundary57","dTTP","C00459_b <=> C00459Cyto",-1000,1000]
[null,58,"Boundary58","dCDP","C00705_b <=> C00705Cyto",-1000,1000]
[null,59,"Boundary59","ATP","C00002_b <=> C00002Cyto",-1000,0]
[null,60,"Boundary60","H+","C00080_b <=> C00080Cyto",-1000,0]
[null,61,"Boundary61","L-Isoleucine","C00407_b <=> C00407Cyto",-1000,3.8999999999999998E-3,"Rat heart",690905]
[null,62,"Boundary62","L-Leucine","C00123_b <=> C00123Cyto",-1000,1.5900000000000001E-2,"Rat heart",690905]
[null,63,"Boundary63","L-Valine","C00183_b <=> C00183Cyto",-1000,1.06E-2,"Rat heart",690905]
[null,64,"Boundary64","Acetaldehyde","C00084_b <=> C00084Cyto",-1000,0]
[null,65,"Boundary65","Hexadecanoic acid","C00249_b + C00080_b <=> C00249Cyto + C00080Cyto",-1000,1,"Rabbit heart",17751291]
[null,66,"Boundary66","(S)-Lactate","C00186_b + C00080_b <=> C00186Cyto + C00080Cyto",-1000,0.57499999999999996,"Dog Heart",7739243]
[null,67,"Boundary67","Fumarate","C00122_b <=> C00122Cyto",-1000,0]
[null,68,"Boundary68","Octanoic acid","C06423_b <=> C06423MM",-1000,1000]
[null,69,"Boundary69","HCO3-","C00288_b <=> C00288Cyto",-1000,1.9800000000000002E-2,"To allow maximum degration of leucine and isoleucine"]
[null,70,"Boundary70","Putrescine","C00134_b <=> C00134Cyto",-1000,1000]
[null,71,"Boundary71","L-Alanine","C00041_b <=> C00041Cyto",-1000,1000]
[null,72,"Boundary72","L-Serine","C00065_b <=> C00065Cyto",-1000,1.66E-2,"Rat heart",690905]
[null,73,"Boundary73","L-Threonine","C00188_b <=> C00188Cyto",-1000,1.1900000000000001E-2,"Rat heart",690905]