Now showing items 1-4 of 4

    • CPEB and miR-15/16 Co-Regulate Translation of Cyclin E1 mRNA during Xenopus Oocyte Maturation 

      Wilczynska, Ania; Git, Anna; Argasinska, Joanna; Belloc, Eulalia; Standart, Nancy Margaret (PLOS, 2016-02-01)
      Cell cycle transitions spanning meiotic maturation of the Xenopus oocyte and early embryogenesis are tightly regulated at the level of stored inactive maternal mRNA. We investigated here the translational control of cyclin ...
    • Double-stranded microRNA mimics can induce length- and passenger strand-dependent effects in a cell type-specific manner 

      Goldgraben, Mae Akilina; Russell, Roslin; Rueda, Oscar M; Caldas, Carlos Manuel; Git, Anna (RNA Society, 2015-12-15)
      MicroRNAs are short (17–26) noncoding RNAs driving or modulating physiological and pathological cellular events. Overexpression of miR-155 is pathogenic in B-cell malignancy but was also reported in a number of solid ...
    • PMC42, a breast progenitor cancer cell line, has normal-like mRNA and miRNA transcriptomes 

      Git, Anna; Spiteri, Inmaculada; Blenkiron, Cherie; Dunning, Mark James; Pole, Jessica CM; Chin, Suet Feung; Wang, Yanzhong et al. (2008-06-27)
      Abstract Introduction The use of cultured cell lines as model systems for normal tissue is limited by the molecular alterations accompanying the immortalisation process, including changes in the mRNA and microRNA (miRNA) ...
    • Subtype-specific micro-RNA expression signatures in breast cancer progression 

      Haakensen, Vilde D; Nygaard, Vegard; Gregers, Liliana; Aure, Miriam R; Fromm, Bastian; Bukholm, Ida RK; Lüders, Torben et al. (Wiley, 2016-04-15)
      Robust markers of invasiveness may help reduce the overtreatment of in situ carcinomas. Breast cancer is a heterogeneous disease and biological mechanisms for carcinogenesis vary between subtypes. Stratification by subtype ...