Now showing items 13210-13229 of 222664

    • G-actin provides substrate-specificity to eukaryotic initiation factor 2a holophosphatases 

      Chen, Ruming; Rato, Claudia Sofia; Yan, Yahui; Crespillo-Casado, Ana; Clarke, Hanna J; Harding, Heather Parish; Marciniak, Stefan John et al. (eLife, 2015-03-16)
      Dephosphorylation of eukaryotic translation initiation factor 2a (eIF2a) restores protein synthesis at the waning of stress responses and requires a PP1 catalytic subunit and a regulatory subunit, PPP1R15A/GADD34 or ...
    • G-equation modelling of thermo-acoustic oscillations of partially-premixed flames 

      Semlitsch, Bernhard; Orchini, A; Dowling, Ann Patricia; Juniper, Matthew Pudan
      Numerical simulations aid combustor design to avoid and reduce thermo-acoustic oscillations. Non-linear heat release rate estimation and its modelling are essential for the prediction of saturation amplitudes of limit ...
    • G-force PD- A global initiative in coordinating stem cell based dopamine treatments for Parkinson’s disease 

      Barker, Roger Alistair; Studer, Lorenz; Cattaneo, Elena; Takahashi, Jun; G-Force, PD consortium (2015-09-24)
      Translating new cell-based therapies to the clinic for patients with neurodegenerative disorders is complex. It involves pre-clinical testing of the cellular product and discussions with several regulatory agencies, as ...
    • G-quadruplex ligands exhibit differential G-tetrad selectivity 

      Le, Daniel Dinh; Di, Antonio M; Chan, Louis Ka; Balasubramanian, Shankar (RSC, 2015-04-03)
      A rapid and simple equilibrium-binding assay mediated by ligand-induced fluorescence quenching of fluorophore-labelled G-quadruplex (G4) structures enabled quantitative interrogation of mutually exclusive ligand binding ...
    • G-quadruplex recognition and isolation with small molecules 

      Müller, Sebastian (2011-01-11)
      An increasing interest in non-canonical nucleic acid structures has drawn the attention of the scientific community during the last few decades. One such structure, the G-quadruplex, has been the focus of an increasing ...
    • G-quadruplex structures mark human regulatory chromatin 

      Hänsel-Hertsch, R; Beraldi, Dario; Lensing, Stefanie; Marsico, Giovanni; Zyner, Katherine Grazyna; Parry, A; Di Antonio, Marco et al. (Nature Publishing Group, 2016-10)
      G-quadruplex (G4) structural motifs have been linked to transcription, replication and genome instability and are implicated in cancer and other diseases. However, it is crucial to demonstrate the bona fide formation of ...
    • G-quadruplex structures within the 3' UTR of LINE-1 elements stimulate retrotransposition 

      Sahakyan, Aleksandr; Murat, P; Mayer, C; Balasubramanian, Shankar (Nature Publishing Group, 2017-03-01)
      Long interspersed nuclear elements (LINEs) are ubiquitous transposable elements in higher eukaryotes that have a significant role in shaping genomes, owing to their abundance. Here we report that guanine-rich sequences in ...
    • G.B. Airy 

      Slater, Isaac Ware; Wageman, Thomas Charles (Institute of Astronomy Library, 1830)
    • G.yang ’bod prayer 

      Dhondup, Yangdon (World Oral Literature Project, 2010-10-04)
      This collection includes ten video files focusing on ritual practices and prayer services of some communities belonging to the Reb kong sngags mang, the community of tantric practitioners from Reb kong. They were recorded ...
    • G11.92−0.61 MM1: a Keplerian disc around a massive young proto-O star 

      Ilee, John David; Cyganowski, CJ; Nazari, P; Hunter, TR; Brogan, CL; Forgan, DH; Zhang, Q (Oxford University Press, 2016-08-09)
      The formation process of massive stars is not well understood, and advancement in our understanding benefits from high-resolution observations and modelling of the gas and dust surrounding individual high-mass (proto)stars. ...
    • G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status 

      Agarwal, Pallavi; Jackson, Stephen Philip (Elsevier, 2016-07-16)
      Cancer cells often exhibit altered epigenetic signatures that can misregulate genes involved in processes such as transcription, proliferation, apoptosis and DNA repair. As regulation of chromatin structure is crucial for ...
    • G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program. 

      Antignano, Frann; Braam, Mitchell; Hughes, Michael R; Chenery, Alistair L; Burrows, Kyle; Gold, Matthew J; Oudhoff, Menno J et al. (2016-06-13)
    • Gaalimasane: a Play. n.d. 

      Mulira, Eridadi M.K.
    • GABRB1 Single Nucleotide Polymorphism Associated with Altered Brain Responses (but not Performance) during Measures of Impulsivity and Reward Sensitivity in Human Adolescents 

      Duka, Theodora; Nikolaou, Kyriaki; King, Sarah L.; Banaschewski, Tobias; Bokde, Arun L. W.; Büchel, Christian; Carvalho, Fabiana M. et al. (2017-02-15)
    • Gadamer's ontology: an examination of Hans-Georg Gadamer's concept of being in relation to Heidegger, Plato and Hegel 

      Dawson, Christopher (Faculty of Philosophy, University of Cambridge, 1996-01-30)
      An examination of the ontological position on which Hans-Georg Gadamer’s views rely, and of its relationship to the views of Heidegger, Plato and Hegel. I argue that Gadamer’s notion of being appeals to a structure he uses ...
    • GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins 

      Harmon, Tyler S; Crabtree, Michael; Shammas, Sarah L; Posey, Ammon E; Clarke, Jane; Pappu, Rohit V (Oxford University Press, 2016-08-08)
      Many intrinsically disordered proteins (IDPs) participate in coupled folding and binding reactions and form alpha helical structures in their bound complexes. Alanine, glycine, or proline scanning mutagenesis approaches ...
    • Gadofosveset-enhanced thoracic MR venography: a comparative study evaluating steady state imaging versus conventional first-pass time-resolved dynamic imaging. 

      See, Teik C; Patterson, Andrew James; Hilliard, Nicholas J; Soh, Ed; Winterbottom, Andrew P; Patterson, Ilse; Parker, Richard A et al. (SAGE Publications, 2017-01)
      $\textbf{Background}$ Dedicated blood-pool contrast agents combined with optimal angiographic protocols could improve the diagnostic accuracy of thoracic magnetic resonance angiography (MRA). $\textbf{Purpose}$ To assess ...
    • Gadolinium Enhancement in Intracranial Atherosclerotic Plaque and Ischemic Stroke: A Systematic Review and Meta-Analysis 

      Gupta, Ajay; Baradaran, Hediyeh; Al-Dasuqi, Khalid; Knight-Greenfield, Ashley; Giambrone, Ashley E; Delgado, Diana; Wright, Drew et al. (American Heart Association, 2016-08-15)
      $\textbf{Background—}$Gadolinium enhancement on high-resolution magnetic resonance imaging (MRI) has been proposed as a marker of inflammation and instability in intracranial atherosclerotic plaque. We performed a systematic ...
    • The Gaia -ESO Survey: Low- α element stars in the Galactic bulge 

      Recio-Blanco, A; Rojas-Arriagada, A; de Laverny, P; Mikolaitis, S; Hill, V; Zoccali, M; Fernández-Trincado, JG et al. (EDP Sciences, 2017-06)
      We take advantage of the Gaia-ESO Survey iDR4 bulge data to search for abundance anomalies that could shed light on the composite nature of the Milky Way bulge. The α-element (Mg, Si, and whenever available, Ca) abundances, ...
    • Gaia data release 1, the photometric data 

      Leeuwen, FV; Evans, Dafydd Wyn; Angeli, FD; Jordi, C; Busso, Giorgia; Cacciari, C; Riello, Marco et al. (EDP Sciences, 2017-03)
      CONTEXT. This paper presents an overview of the photometric data that are part of the first Gaia data release. AIMS. The principles of the processing and the main characteristics of the Gaia photometric data are presented. ...