Now showing items 1-7 of 7

    • An anterior medial cell population with an apical-organ-like transcriptional profile that pioneers the central nervous system in the centipede Strigamia maritima 

      Hunnekuhl, Vera S.; Akam, Michael (Elsevier, 2014)
      The apical plate of primary marine larvae is characterized by a common set of 5 transcription factors comprising six3, rx, hbn, nk2.1 and FoxQ2. It harbours the 6 apical organ, a neural and ciliary structure with neurosecretory ...
    • Appendage development and early Distal-less regulation in arthropods: A study of the chelicerate Tetranychus urticae (Acarida) 

      Cyrus-Kent, Chloë (2007-12-08)
      A major goal of evolutionary developmental biology is to explore mechanisms and events underlying evolution of the myriad body plan morphologies expressed both genetically and phenotypically within the animal kingdom. ...
    • The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima 

      Chipman, Ariel D.; Ferrier, David E. K.; Brena, Carlo; Qu, Jiaxin; Hughes, Daniel S. T.; Schröder, Reinhard; Torres-­Oliva, Montserrat et al. (PLOS, 2014)
      Myriapods (e.g., centipedes and millipedes) display a simple homonomous body plan relative to other arthropods. All members of the class are terrestrial, but they attained terrestriality independently of insects. Myriapoda ...
    • Germ cells of the centipede Strigamia maritima are specified early in embryonic development 

      Green, Jack E.; Akam, Michael (Elsevier, 2014-06-12)
      We provide the first systematic description of germ cell development with molecular markers in a myriapod, the centipede Strigamia maritima. By examining the expression of Strigamia vasa and nanos orthologues, we find that ...
    • Odd-paired controls frequency doubling in Drosophila segmentation by altering the pair-rule gene regulatory network 

      Clark, Erik; Akam, Michael (eLife, 2016-08-15)
      The Drosophila embryo transiently exhibits a double-segment periodicity, defined by the expression of seven 'pair-rule' genes, each in a pattern of seven stripes. At gastrulation, interactions between the pair-rule genes ...
    • Six3 demarcates the anterior-most developing brain region in bilaterian animals 

      Steinmetz, Patrick R H; Urbach, Rolf; Posnien, Nico; Eriksson, Joakim; Kostyuchenko, Roman P; Brena, Carlo; Guy, Keren et al. (2010-12-29)
      Abstract Background The heads of annelids (earthworms, polychaetes, and others) and arthropods (insects, myriapods, spiders, and others) and the arthropod-related onychophorans (velvet worms) show similar brain architecture ...
    • XX/XY system of sex determination in the geophilomorph centipede Strigamia maritima 

      Green, Jack E.; Dalíková, Martina; Sahara, Ken; Marec, František; Akam, Michael (PLOS, 2016)
      We show that the geophilomorph centipede Strigamia maritima possesses an XX/XY system of sex chromosomes, with males being the heterogametic sex. This is, to our knowledge, the first report of sex chromosomes in any ...