Now showing items 1-14 of 14

    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F et al. (2012-05-14)
      Abstract Introduction Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with ...
    • Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population 

      Duarte-Salles, Talita; Misra, Sandeep; Stepien, Magdalena; Plymoth, Amelie; Muller, David C; Overvad, Kim; Olsen, Anja et al. (American Association for Cancer Research, 2016-06-23)
      We previously identified osteopontin (OPN) as a promising marker for the early detection of hepatocellular carcinoma (HCC). In this study, we investigated the association between pre-diagnostic circulating OPN levels and ...
    • Coffee Drinking and Mortality in 10 European Countries: A Multinational Cohort Study 

      Gunter, Marc J; Murphy, Neil; Cross, Amanda J; Dossus, Laure; Dartois, Laureen; Fagherazzi, Guy; Kaaks, Rudolf et al. (American College of Physicians, 2017-08-15)
      Background: The relationship between coffee consumption and mortality in diverse European populations with variable coffee preparation methods is unclear. Objective: To examine whether coffee consumption is associated with ...
    • A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study. 

      Imamura, Fumiaki; Sharp, Stephen John; Koulman, Albert; Schulze, Matthias B; Kröger, Janine; Griffin, Julian Leether; Huerta, José M et al. (Public Library of Science (PLoS), 2017-10-11)
      Background: Combinations of multiple fatty acids may influence cardiometabolic risk more than single fatty acids. The association of a combination of fatty acids with incident type 2 diabetes (T2D) has not been evaluated. Methods ...
    • Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohort 

      Fortner, Renée T; Vitonis, Allison F; Schock, Helena; Hüsing, Anika; Johnson, Theron; Fichorova, Raina N; Fashemi, Titilayo et al. (2017-03-20)
      Abstract Background Ovarian cancer early detection markers CA125, CA15.3, HE4, and CA72.4 vary between healthy women, limiting their utility for screening. ...
    • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort. 

      Zamora-Ros, Raul; Barupal, Dinesh K; Rothwell, Joseph A; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira et al. (John Wiley & Sons Inc., 2017-04)
      Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in ...
    • Erratum. Dietary protein intake and incidence of type 2 diabetes in europe: the EPIC-InterAct case-cohort study. Diabetes Care 2014;37:1854-1862. 

      van Nielen, Monique; Feskens, Edith JM; Mensink, Marco; Sluijs, Ivonne; Molina, Esther; Amiano, Pilar; Ardanaz, Eva et al. (2015-10)
    • The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk 

      Campa, Daniele; Husing, Anika; McKay, James D; Sinilnikova, Olga M; Vogel, Ulla; Tjonneland, Anne; Overvad, Kim et al. (2010-10-18)
      Abstract Background The single nucleotide polymorphism rs7566605, located in the promoter of the INSIG2 gene, has been the subject of a strong scientific effort aimed to elucidate its possible association with body mass ...
    • Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries. 

      Li, Sherly X; Imamura, Fumiaki; Schulze, Matthias B; Zheng, Jusheng; Ye, Zheng; Agudo, Antonio; Ardanaz, Eva et al. (Springer Nature, 2018-03-17)
      Abstract Aims/hypothesis: Gene-macronutrient interactions may contribute to the development of type 2 diabetes but evidence is inconclusive. Methods: We investigated interactions between genetic risk scores (GRSs) for ...
    • Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study. 

      Moskal, Aurélie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T; Jenab, Mazda; Ferrari, Pietro et al. (2016-11)
    • Modifiable causes of premature death in middle-age in Western Europe: results from the EPIC cohort study. 

      Muller, David C; Murphy, Neil; Johansson, Mattias; Ferrari, Pietro; Tsilidis, Konstantinos K; Boutron-Ruault, Marie-Christine; Clavel, Francoise et al. (BioMed Central, 2016-06-14)
      BACKGROUND: Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, ...
    • Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort 

      Fortner, Renée T; Sarink, Danja; Schock, Helena; Johnson, Theron; Tjønneland, Anne; Olsen, Anja; Overvad, Kim et al. (2017-02-08)
      Abstract Background Circulating osteoprotegerin (OPG), a member of the receptor activator of nuclear factor kappa-B (RANK) axis, may influence breast cancer risk via its role ...
    • Physical Activity and all-cause mortality across levels of general and abdominal adiposity: The European Prospective Investigation into Cancer and Nutrition Study (EPIC) 

      Ekelund, Ulf Mikael; Ward, Heather A; Norat, Teresa; Luan, Jian'an; May, Anne M; Weiderpass, Elisabete; Sharp, Stephen John et al. (American Society for Nutrition, 2015-01-14)
      Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number of deaths reduced by eliminating physical inactivity compared with overall ...
    • Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort 

      Hughes, David J; Duarte-Salles, Talita; Hybsier, Sandra; Trichopoulou, Antonia; Stepien, Magdalena; Aleksandrova, Krasimira; Overvad, Kim et al. (American Society for Nutrition, 2016-06-29)
      Background: Selenium status is suboptimal in many Europeans and may be a risk factor for the development of various cancers, including those of the liver and biliary tract. Objective: We wished to examine whether selenium ...