Now showing items 3-17 of 17

    • Defining the broader, medium and narrow autism phenotype among parents using the Autism Spectrum Quotient (AQ) 

      Wheelwright, Sally; Auyeung, Bonnie; Allison, Carrie; Baron-Cohen, Simon (2010-06-17)
      Abstract Background The Autism Spectrum Quotient (AQ) is a self-report questionnaire for quantifying autistic traits. This study tests whether the AQ can differentiate between parents of children with an autism spectrum ...
    • Foetal testosterone and autistic traits in 18 to 24-month-old children 

      Auyeung, Bonnie; Taylor, Kevin; Hackett, Gerald; Baron-Cohen, Simon (2010-07-12)
      Abstract Background Autism spectrum conditions have been characterised as an extreme presentation of certain male-typical psychological traits. In addition, several studies have established a link between prenatal exposure ...
    • Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing 

      Lombardo, Michael V.; Auyeung, Bonnie; Holt, Rosemary J.; Waldman, Jack; Ruigrok, Amber N. V.; Mooney, Natasha; Bullmore, Edward T. et al. (Elsevier, 2016-07-11)
      Functional magnetic resonance imaging (fMRI) research is routinely criticized for being statistically underpowered due to characteristically small sample sizes and much larger sample sizes are being increasingly recommended. ...
    • Measuring autistic traits in the general population: a systematic review of the Autism-Spectrum Quotient (AQ) in a nonclinical population sample of 6,900 typical adult males and females 

      Ruzich, E.; Allison, Carrie; Smith, Paula; Watson, Peter; Auyeung, Bonnie; Ring, Howard; Baron-Cohen, Simon (BioMed Central, 2015-01-14)
      The Autism-Spectrum Quotient (AQ) is a self-report measure of autistic traits. It is frequently cited in diverse fields and has been administered to adults of at least average intelligence with autism and to nonclinical ...
    • Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age 

      Auyeung, Bonnie; Ahluwalia, Jag; Thomson, Lynn; Taylor, Kevin; Hackett, Gerald; O’Donnell, Kieran J; Baron-Cohen, Simon (2012-12-11)
      Abstract Background Studies of prenatal exposure to sex steroid hormones predict autistic traits in children at 18 to 24 and at 96 months of age. However, it is not known whether postnatal exposure to these hormones has a ...
    • Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis 

      Sun, Xiang; Allison, Carrie; Matthews, Fiona E; Sharp, Stephen J; Auyeung, Bonnie; Baron-Cohen, Simon; Brayne, Carol (2013-04-09)
      Abstract Background The prevalence of autism spectrum conditions (ASC) is 1% in developed countries, but little data are available from mainland China, Hong Kong and Taiwan. This study synthesizes evidence relating to the ...
    • Quantifying and exploring camouflaging in men and women with autism 

      Lai, Meng-Chuan; Lombardo, Michael V.; Ruigrok, Amber N. V.; Chakrabarti, Bhismadev; Auyeung, Bonnie; MRC AIMS Consortium; Szatmari, Peter et al. (SAGE Publications, 2016-11-30)
      Autobiographical descriptions and clinician observations suggest that some individuals with autism, particularly females, ‘camouflage’ their social-communication difficulties, which may require considerable cognitive effort ...
    • The “Reading the Mind in the Eyes” test: Complete absence of typical sex difference in ~400 men and women with autism 

      Baron-Cohen, Simon; Bowen, Daniel C.; Holt, Rosemary J.; Allison, Carrie; Auyeung, Bonnie; Lombardo, Michael V.; Smith, Paula et al. (PLoS, 2015)
      The “Reading the Mind in the Eyes” test (Eyes test) is an advanced test of theory of mind. Typical sex difference has been reported (i.e., female advantage). Individuals with autism show more difficulty than do typically ...
    • Sex/Gender Differences and Autism: Setting the Scene for Future Research 

      Lai, Meng-Chuan; Lombardo, Michael V.; Auyeung, Bonnie; Chakrabarti, Bhismadev; Baron-Cohen, Simon (Elsevier, 2014-10-16)
      Objective: The relationship between sex/gender differences and autism has attracted a variety of research ranging from clinical and neurobiological to etiological, stimulated by the male bias in autism prevalence. ...
    • Subgrouping siblings of people with autism: identifying the broader autism phenotype 

      Ruzich, Emily; Allison, Carrie; Smith, Paula; Watson, Peter; Auyeung, Bonnie; Ring, Howard; Baron-Cohen, Simon (Wiley, 2015-09-02)
      We investigate the broader autism phenotype (BAP) in siblings of individuals with autism spectrum conditions (ASC). Autistic traits were measured in typical controls (n = 2,000), siblings (n = 496), and volunteers with ASC ...
    • The EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation 

      Charman, Tony; Loth, Eva; Tillmann, Julian; Crawley, Daisy; Wooldridge, Caroline; Goyard, David; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism ...
    • The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders 

      Loth, Eva; Charman, Tony; Mason, Luke; Tillmann, Julian; Jones, Emily J H; Wooldridge, Caroline; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of ...
    • Unsupervised data-driven stratification of mentalizing heterogeneity in autism 

      Lombardo, Michael V.; Lai, Meng-Chuan; Auyeung, Bonnie; Holt, Rosemary J.; Allison, Carrie; Smith, Paula; Chakrabarti, Bhismadev et al. (Nature Publishing Group, 2016-10-18)
      Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a ...
    • Validation of existing diagnosis of autism in mainland China using standardised diagnositc instruments 

      Sun, Xiang; Allison, Carrie; Auyeung, Bonnie; Zhixiang, Zhang; Matthews, Fiona E.; Baron-Cohen, Simon; Brayne, Carol (SAGE, 2015-03-10)
      Research to date in mainland China has mainly focused on children with autistic disorder rather than Autism Spectrum Conditions and the diagnosis largely depended on clinical judgment without the use of diagnostic instruments. ...
    • Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children 

      Tavassoli, Teresa; Auyeung, Bonnie; Murphy, Laura C; Baron-Cohen, Simon; Chakrabarti, Bhismadev (2012-07-06)
      AbstractBackgroundAutism spectrum conditions have a strong genetic component. Atypical sensory sensitivities are one of the core but neglected features of autism spectrum conditions. GABRB3 is a well-characterised candidate ...