Now showing items 13-17 of 17

    • The EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation 

      Charman, Tony; Loth, Eva; Tillmann, Julian; Crawley, Daisy; Wooldridge, Caroline; Goyard, David; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism ...
    • The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders 

      Loth, Eva; Charman, Tony; Mason, Luke; Tillmann, Julian; Jones, Emily J H; Wooldridge, Caroline; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of ...
    • Unsupervised data-driven stratification of mentalizing heterogeneity in autism 

      Lombardo, Michael V.; Lai, Meng-Chuan; Auyeung, Bonnie; Holt, Rosemary J.; Allison, Carrie; Smith, Paula; Chakrabarti, Bhismadev et al. (Nature Publishing Group, 2016-10-18)
      Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a ...
    • Validation of existing diagnosis of autism in mainland China using standardised diagnositc instruments 

      Sun, Xiang; Allison, Carrie; Auyeung, Bonnie; Zhixiang, Zhang; Matthews, Fiona E.; Baron-Cohen, Simon; Brayne, Carol (SAGE, 2015-03-10)
      Research to date in mainland China has mainly focused on children with autistic disorder rather than Autism Spectrum Conditions and the diagnosis largely depended on clinical judgment without the use of diagnostic instruments. ...
    • Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children 

      Tavassoli, Teresa; Auyeung, Bonnie; Murphy, Laura C; Baron-Cohen, Simon; Chakrabarti, Bhismadev (2012-07-06)
      AbstractBackgroundAutism spectrum conditions have a strong genetic component. Atypical sensory sensitivities are one of the core but neglected features of autism spectrum conditions. GABRB3 is a well-characterised candidate ...