Now showing items 33-46 of 46

    • Self-referential and social cognition in a case of autism and agenesis of the corpus callosum 

      Lombardo, Michael V; Chakrabarti, Bhismadev; Lai, Meng-Chuan; MRC AIMS Consortium; Baron-Cohen, Simon (2012-11-21)
      Abstract Background While models of autism spectrum conditions (ASC) are emerging at the genetic level of analysis, clear models at higher levels of analysis, such as neuroanatomy, are lacking. Here we examine agenesis of ...
    • Self-referential cognition and empathy in autism 

      Lombardo, Michael V.; Barnes, Jennifer L.; Wheelwright, Sally J.; Baron-Cohen, Simon (PLoS One, 2007)
      Background. Individuals with autism spectrum conditions (ASC) have profound impairments in the interpersonal social domain, but it is unclear if individuals with ASC also have impairments in the intrapersonal self-referential ...
    • Semi-Metric Topology of the Human Connectome: Sensitivity and Specificity to Autism and Major Depressive Disorder 

      Simas, Tiago; Chattopadhyay, Shayanti; Hagan, Cindy; Kundu, Prantik; Patel, Ameera; Rosemary, Holt; Floris, Dorothea et al. (PLOS, 2015-08-26)
      Introduction: The human functional connectome is a graphical representation, consisting of nodes connected by edges, of the inter-relationships of blood oxygenation-level dependent (BOLD) time-series measured by MRI from ...
    • Sex and STEM occupation predict Autism-Spectrum Quotient (AQ) scores in half a million people 

      Ruzich, Emily; Allison, Carrie; Chakrabarti, Bhismadev; Smith, Paula; Musto, Henry; Ring, Howard; Baron-Cohen, Simon (PLoS, 2015-10-21)
      This study assesses Autism-Spectrum Quotient (AQ) scores in a ‘big data’ sample collected through the UK Channel 4 television website, following the broadcasting of a medical education program. We examine correlations ...
    • Sex/Gender Differences and Autism: Setting the Scene for Future Research 

      Lai, Meng-Chuan; Lombardo, Michael V.; Auyeung, Bonnie; Chakrabarti, Bhismadev; Baron-Cohen, Simon (Elsevier, 2014-10-16)
      Objective: The relationship between sex/gender differences and autism has attracted a variety of research ranging from clinical and neurobiological to etiological, stimulated by the male bias in autism prevalence. ...
    • Spatial localisation in autism: evidence for differences in early cortical visual processing 

      Latham, Keziah; Chung, Susana T. L.; Allen, Peter M.; Tavassoli, Teresa; Baron-Cohen, Simon (2013-02-19)
      Abstract Background Vision in people with autism spectrum conditions (ASC) is reported to be different from people without ASC, but the neural level at which the differences begin to occur is not yet known. Here we examine ...
    • Subgrouping siblings of people with autism: identifying the broader autism phenotype 

      Ruzich, Emily; Allison, Carrie; Smith, Paula; Watson, Peter; Auyeung, Bonnie; Ring, Howard; Baron-Cohen, Simon (Wiley, 2015-09-02)
      We investigate the broader autism phenotype (BAP) in siblings of individuals with autism spectrum conditions (ASC). Autistic traits were measured in typical controls (n = 2,000), siblings (n = 496), and volunteers with ASC ...
    • Task-related functional connectivity in autism spectrum conditions: an EEG study using wavelet transform coherence 

      Catarino, Ana; Andrade, Alexandre; Churches, Owen; Wagner, Adam P.; Baron-Cohen, Simon; Ring, Howard (2013-01-12)
      Abstract Background Autism Spectrum Conditions (ASC) are a set of pervasive neurodevelopmental conditions characterized by a wide range of lifelong signs and symptoms. Recent explanatory models of autism propose abnormal ...
    • Testing the ‘extreme female brain’ theory of psychosis in adults with autism spectrum disorder with or without co-morbid psychosis 

      Larson, Felicity V.; Lai, Meng-Chuan; Wagner, Adam P.; MRC AIMS Consortium; Baron-Cohen, Simon; Holland, Anthony J. (PLOS, 2015-06-12)
      Introduction: Males and females in the general population differ, on average, in their drive for empathizing (higher in females) and systemizing (higher in males). People with autism spectrum disorder (ASD) show a drive ...
    • Typical Magnitude and Spatial Extent of Crowding in Autism 

      Freyberg, Jan; Robertson, Caroline E.; Baron-Cohen, Simon (Association for Research in Vision and Ophthalmology, 2016)
      Enhanced spatial processing of local visual details has been reported in individuals with Autism Spectrum Conditions (ASC), and crowding is postulated to be a mechanism that may produce this ability. However, evidence for ...
    • Unsupervised data-driven stratification of mentalizing heterogeneity in autism 

      Lombardo, Michael V.; Lai, Meng-Chuan; Auyeung, Bonnie; Holt, Rosemary J.; Allison, Carrie; Smith, Paula; Chakrabarti, Bhismadev et al. (Nature Publishing Group, 2016-10-18)
      Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a ...
    • Validation of existing diagnosis of autism in mainland China using standardised diagnositc instruments 

      Sun, Xiang; Allison, Carrie; Auyeung, Bonnie; Zhixiang, Zhang; Matthews, Fiona E.; Baron-Cohen, Simon; Brayne, Carol (SAGE, 2015-03-10)
      Research to date in mainland China has mainly focused on children with autistic disorder rather than Autism Spectrum Conditions and the diagnosis largely depended on clinical judgment without the use of diagnostic instruments. ...
    • Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children 

      Tavassoli, Teresa; Auyeung, Bonnie; Murphy, Laura C; Baron-Cohen, Simon; Chakrabarti, Bhismadev (2012-07-06)
      AbstractBackgroundAutism spectrum conditions have a strong genetic component. Atypical sensory sensitivities are one of the core but neglected features of autism spectrum conditions. GABRB3 is a well-characterised candidate ...
    • Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces 

      Chakrabarti, Bhismadev; Baron-Cohen, Simon (2011-06-29)
      Abstract Background From an early age, humans look longer at preferred stimuli and also typically look longer at facial expressions of emotion, particularly happy faces. Atypical gaze patterns towards social stimuli are ...