Now showing items 1-4 of 4

    • Characterisation of microRNA expression in post-natal mouse mammary gland development 

      Avril-Sassen, Stefanie; Goldstein, Leonard D.; Stingl, John; Blenkiron, Cherie; Le Quesne, John; Spiteri, Inmaculada; Karagavriilidou, Konstantina et al. (2009-11-20)
      Abstract Background The differential expression pattern of microRNAs (miRNAs) during mammary gland development might provide insights into their role in regulating the homeostasis of the mammary epithelium. Our aim was to ...
    • Differential expression of selected histone modifier genes in human solid cancers 

      Ozdag, Hilal; Teschendorff, Andrew E.; Ahmed, Ahmed A.; Hyland, Sarah J.; Blenkiron, Cherie; Bobrow, Linda; Veerakumarasivam, Abhi et al. (2006-04-25)
      Abstract Background Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we report characteristic patterns of expression of 12 members ...
    • MicroRNA expression profiling of human breast cancer identifies new markers of tumour subtype 

      Blenkiron, Cherie; Goldstein, Leonard D.; Thorne, Natalie P.; Spiteri, Inmaculada; Chin, Suet-Feung; Dunning, Mark J.; Barbosa-Morais, Nuno L. et al. (2007-10-08)
      Abstract Background MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants and animals, often act post-transcriptionally to inhibit gene expression. Results Here we report the analysis of miRNA expression ...
    • PMC42, a breast progenitor cancer cell line, has normal-like mRNA and miRNA transcriptomes 

      Git, Anna; Spiteri, Inmaculada; Blenkiron, Cherie; Dunning, Mark J.; Pole, Jessica C. M.; Chin, Suet-Feung; Wang, Yanzhong et al. (2008-06-27)
      Abstract Introduction The use of cultured cell lines as model systems for normal tissue is limited by the molecular alterations accompanying the immortalisation process, including changes in the mRNA and microRNA (miRNA) ...