Now showing items 12-31 of 38

    • The Descriptive Epidemiology of the Diurnal Profile of Bouts and Breaks in Sedentary Time in English Older Adults 

      Yerrakalva, Dharani; Cooper, Andrew John; Westgate, Kathryn Louise; Khaw, Kay-Tee; Wareham, Nicholas John; Brage, Soren; Griffin, Simon James et al. (OUP, 2017-08-08)
      Background: High sedentary time is associated with adverse metabolic health outcomes and mortality in older adults. It has been suggested that breaking up sedentary time may be beneficial for metabolic health; however, ...
    • Estimation of Physical Activity Energy Expenditure during Free-Living from Wrist Accelerometry in UK Adults. 

      White, Tom; Westgate, Kathryn Louise; Wareham, Nicholas John; Brage, Soren (Public Library of Science (PLoS), 2016-01)
    • Frequency and duration of physical activity bouts in school-aged children: A comparison within and between days 

      Brooke, HL; Atkin, Andrew James; Corder, Kirsten Liane; Brage, Soren; van Sluijs, Esther Maria (Elsevier, 2016-12-01)
      Understanding how physical activity (PA) patterns vary within and between days may guide PA promotion in young people. We aimed to 1) describe and compare the frequency (bouts/day) and duration (min/bout) of bouts of ...
    • Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 

      Graff, Mariaelisa; Scott, Robert A; Justice, Anne E; Young, Kristin L; Feitosa, Mary F; Barata, Llilda; Winkler, Thomas W et al. (2017-04-27)
    • Home and Work Physical Activity Environments: Associations with Cardiorespiratory Fitness and Physical Activity Level in French Women 

      Oppert, J-M; Charles, M-A; Charreire, H; Menai, M; De Bourdeaudhuij, I; Brage, Soren; de Lauzon-Guillain, B et al. (MDPI, 2016-08-15)
      The influence of the physical activity environment in the home and at work on cardiorespiratory fitness (CRF) and objectively-measured physical activity has not been extensively studied. We recruited 147 women with a (mean ...
    • Impact of sit-stand desks at work on energy expenditure and sedentary time: protocol for a feasibility study 

      Mantzari, Eleni; Wijndaele, Katrien; Brage, Soren; Griffin, Simon J.; Marteau, Theresa M. (BioMed Central, 2016-07-18)
      ${\bf Background:}$ Prolonged sitting, an independent risk factor for disease development and premature mortality, is increasing in prevalence in high- and middle-income countries, with no signs of abating. Adults in such ...
    • Impact of sit-stand desks at work on energy expenditure and sedentary time: protocol for a feasibility study. 

      Mantzari, Eleni; Wijndaele, Katrien Lieve; Brage, Soren; Griffin, Simon James; Marteau, Theresa, M (BioMed Central, 2016-07-18)
      BACKGROUND: Prolonged sitting, an independent risk factor for disease development and premature mortality, is increasing in prevalence in high- and middle-income countries, with no signs of abating. Adults in such countries ...
    • Independent and joint associations of grip strength and adiposity with all-cause and cardiovascular disease mortality in 403,199 adults: the UK Biobank study. 

      Kim, Youngwon; Wijndaele, Katrien; Lee, Duck-Chul; Sharp, Stephen J; Wareham, Nicholas John; Brage, Soren (American Society for Clinical Nutrition, Inc., 2017-09)
    • Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study 

      Doherty, A; Jackson, D; Hammerla, N; Plötz, T; Olivier, P; Granat, MH; White, Tom et al. (Public Library of Science (PLoS), 2017-02-01)
      BACKGROUND: Physical activity has not been objectively measured in prospective cohorts with sufficiently large numbers to reliably detect associations with multiple health outcomes. Technological advances now make this ...
    • Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness 

      Willems, SM; Wright, Daniel; Day, Felix Ranulf; Trajanoska, K; Joshi, PK; Morris, JA; Matteini, AM et al. (Nature Publishing Group, 2017-07-12)
      Hand grip strength is a widely used proxy of muscular fitness, a marker of frailty, and predictor of a range of morbidities and all-cause mortality. To investigate the genetic determinants of variation in grip strength, ...
    • Mediation and modification of genetic susceptibility to obesity by eating behaviors. 

      de Lauzon-Guillain, Blandine; Clifton, Emma; Day, Felix Ranulf; Clément, Karine; Brage, Soren; Forouhi, Nita Gandhi; Griffin, Simon James et al. (American Society for Clinical Nutrition, Inc., 2017-08-16)
      $\textbf{}$Background: Many genetic variants show highly robust associations with body mass index (BMI). However, the mechanisms through which genetic susceptibility to obesity operates are not well understood. Potentially ...
    • Mortality Risk Reductions from Substituting Screen Time by Discretionary Activities. 

      Wijndaele, Katrien Lieve; Sharp, Stephen John; Wareham, Nicholas John; Brage, Soren (Lippincott Williams & Wilkins Ltd., 2017-06)
      $\textbf{Purpose:}$ Leisure-screen-time, including TV viewing, is associated with increased mortality risk. We estimated the all-cause mortality risk reductions associated with substituting leisure-screen-time with different ...
    • Objective Measures of Activity in the Elderly: Distribution and Associations With Demographic and Health Factors. 

      Koolhaas, Chantal M; van Rooij, Frank JA; Schoufour, Josje D; Cepeda, Magda; Tiemeier, Henning; Brage, Soren; Franco, Oscar H (Elsevier, 2017-06-08)
    • Physical activity and incident type 2 diabetes mellitus: a systematic review and dose-response meta-analysis of prospective cohort studies. 

      Smith, AD; Crippa, A; Woodcock, James David; Brage, Soren (Springer, 2016-12)
      AIMS/HYPOTHESIS: Inverse associations between physical activity (PA) and type 2 diabetes mellitus are well known. However, the shape of the dose-response relationship is still uncertain. This review synthesises results ...
    • Physical activity and sedentary time in relation to academic achievement in children. 

      Haapala, EA; Väistö, J; Lintu, N; Westgate, Kathryn Louise; Ekelund, U; Poikkeus, A-M; Brage, Soren et al.
      OBJECTIVES: To investigate the independent and combined associations of objectively measured moderate-to-vigorous physical activity (MVPA) and sedentary time (ST) with reading and arithmetic skills. DESIGN: Cross-section ...
    • Physical activity levels objectively measured among older adults: a population-based study in a Southern city of Brazil 

      Ramires, Virgílio V; Wehrmeister, Fernando C; Böhm, Andrea W; Galliano, Leony; Ekelund, Ulf; Brage, Soren; da Silva, Inácio C M (2017-02-02)
      Abstract Background Low levels of physical activity are currently observed in all age groups around the world. Among older adults physical activity is even lower, potentially ...
    • Physical activity levels objectively measured among older adults: a population-based study in a Southern city of Brazil 

      Ramires, VV; Wehrmeister, FC; Wendt Böhm, A; Galliano, L; Ekelund, U; Brage, Soren; Crochemore Mohnsam da Silva, I
      $\textbf{Background:}$ Low levels of physical activity are currently observed in all age groups around the world. Among older adults physical activity is even lower, potentially influencing quality of life, incidence of ...
    • Physical activity throughout adolescence and HbA1c in early adulthood: birth cohort study 

      Nakamura, PM; Mielke, GI; Horta, BL; Assunção, MC; Gonçalves, H; Menezes, AMB; Barros, FC et al.
      Background: Physical inactivity is responsible for 7% of diabetes deaths worldwide, but little is known whether low levels of physical activity (PA) during adolescence increase the risk of diabetes in early adulthood. We ...
    • Physical Activity, Sedentary Time, and Fatness in a Biethnic Sample of Young Children. 

      Collings, PJ; Brage, Soren; Bingham, DD; Costa, Silvia Susana; West, J; McEachan, RR; Wright, J et al. (Wolters Kluwer, 2017-01-03)
      PURPOSE: To investigate associations of objectively-measured physical activity (PA) and sedentary time (ST) with adiposity in a predominantly bi-ethnic (South Asian and White British) sample of young children. METHODS: The ...
    • Protocol for Get Moving: a randomised controlled trial to assess the effectiveness of three minimal contact interventions to promote fitness and physical activity in working adults 

      Cooper, Andrew J; Dearnley, Katie; Williams, Kate M; Sharp, Stephen J; van Sluijs, Esther M; Brage, Soren; Sutton, Stephen et al. (2015-03-27)
      Abstract Background Web-based interventions for physical activity offer several advantages over face-to-face, print-and telephone-based interventions and are scalable and ...