Now showing items 1-20 of 52

• #### A commentary on studies presenting projections of the future prevalence of dementia ﻿

(2013-01-02)
Abstract Background Population ageing over the first half of this century is likely to lead to dramatic increases in the prevalence of dementia. This will affect all regions of the world, but particularly developing regions. ...
• #### A comparison of parametric models for the investigation of the shape of cognitive change in the older population. ﻿

(2008-05-16)
Abstract Background Cognitive decline is a major threat to well being in later life. Change scores and regression based models have often been used for its investigation. Most methods used to describe cognitive decline ...
• #### An investigation of the population impact of variation in HbA1c levels in older people in England and Wales: from a population based multi-centre longitudinal study ﻿

(2008-02-11)
Abstract Background Diabetes is common in the older population and is increasing. Glycated hemoglobin (HbA1c) is an indicator of average blood glucose concentration over the past three months. The HbA1c test is currently ...
• #### An investigation of whether factors associated with short-term attrition change or persist over ten years: data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) ﻿

(2006-07-18)
Abstract Background Factors associated with the loss of participants in long-term longitudinal studies of ageing, due to refusal or moves, have been discussed less than those with short term follow-up. Methods In a ...
• #### Assessing environmental features related to mental health: a reliability study of visual streetscape images Assessing environmental features related to mental health: a reliability study of visual streetscape images ﻿

(BioMed Central, 2014-10-22)
Background: An association between depressive symptoms and features of built environment has been reported in the literature. A remaining research challenge is the development of methods to efficiently capture pertinent ...
• #### The association between community environment and cognitive function: a systematic review ﻿

(Springer, 2014-08-03)
Purposes: The aim of this study is to review the published evidence on the association between community environment and cognitive function in older people, focusing on the findings and a critique of the existing studies. ...
• #### The association between depressive symptoms in the community, non-psychiatric hospital admission and hospital outcomes: a systematic review. ﻿

(Elsevier, 2014-11-08)
Objectives This paper aims to systematically review observational studies that have analysed whether depressive symptoms in the community are associated with higher general hospital admissions, longer hospital stays and ...
• #### Attitudes and preferences towards screening for dementia: a systematic review of the literature ﻿

(BioMed Central, 2015-06-16)
Background Population screening might provide a mechanism to enable early detection of dementia. Yet the potential benefits, harms or acceptability of such a large-scale intervention are not well understood. This research ...
• #### Barriers and Facilitators to the Uptake and Maintenance of Healthy Behaviours by People at Mid-Life: A Rapid Systematic Review ﻿

(PLOS, 2016-01-27)
Background With an ageing population, there is an increasing societal impact of ill health in later life. People who adopt healthy behaviours are more likely to age successfully. To engage people in health promotion ...
• #### Behavioural and psychological symptoms in the older population without dementia - relationship with socio-demographics, health and cognition ﻿

(2010-11-30)
Abstract Background Behavioural and psychological symptoms are associated with dementia, but are also present in a significant number of the older population without dementia. Here we explore the distribution of behavioural ...
• #### Behavioural Risk Factors in Mid-Life Associated with Successful Ageing, Disability, Dementia and Frailty in Later Life: A Rapid Systematic Review ﻿

(PLOS, 2016-02-04)
Background Smoking, alcohol consumption, poor diet and low levels of physical activity significantly contribute to the burden of illness in developed countries. Whilst the links between specific and multiple risk ...
• #### The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing ﻿

(BioMed Central, 2014-10-14)
Background As greater numbers of us are living longer, it is increasingly important to understand how we can age healthily. Although old age is often stereotyped as a time of declining mental abilities and inflexibility, ...
• #### Changing non-participation in epidemiological studies of older people: evidence from the Cognitive Function and Ageing Study I and II ﻿

(OUP, 2015-08-14)
Background: non-participation in epidemiological studies threatens the generalisability of findings. Objective: to investigate the change in non-participation between the Medical Research Council Cognitive Function and ...
• #### Cognitive function in a general population of men and women: A cross sectional study in the European Investigation of Cancer–Norfolk cohort (EPIC-Norfolk) ﻿

(BioMed Central, 2014-12-19)
Background: Although ageing is strongly associated with cognitive decline, a wide range of cognitive ability is observed in older populations with varying rates of change across different cognitive domains. Objective: We ...
• #### Cohort differences in disease and disability in the young-old: findings from the MRC Cognitive Function and Ageing Study (MRC-CFAS) ﻿

(2007-07-13)
Abstract Background Projections of health and social care need are highly sensitive to assumptions about cohort trends in health and disability. We use a repeated population-based cross-sectional study from the Cambridgeshire ...
• #### Community environment, cognitive impairment and dementia in later life: results from the Cognitive Function and Ageing Study ﻿

(Oxford University Press, 2015-10-13)
Background: Few studies have investigated the impact of the community environment, as distinct from area deprivation, on cognition in later life. This study explores cross-sectional associations between cognitive impairment ...
• #### Daytime napping and increased risk of incident respiratory diseases: symptom, marker, or risk factor? ﻿

(Elsevier, 2016-07-12)
$\textit{Background:}$ We have identified a strong association between daytime napping and increased mortality risk from respiratory diseases, but little is known about the relationship between daytime napping and respiratory ...
• #### Daytime napping, sleep duration and serum C-reactive protein: a population-based cohort study ﻿

(BMJ Group, 2014-11-11)
Objectives: To explore whether daytime napping and sleep duration are linked to serum C-reactive protein (CRP), a pro-inflammatory marker, in an older-aged British population. Design: Cross-sectional study Setting: ...
• #### Death and the Oldest Old: Attitudes and Preferences for End-of-Life Care Qualitative Research within a Population-Based Cohort Study ﻿

(Public Library Of Science, 2016)
Introduction: Increasing longevity means more people will be dying in very old age, but little is known about the preferences of the ‘oldest old’ regarding their care at the end of life. Aims: To understand very old ...
• #### Dementia in western Europe: epidemiological evidence and implications for policy making ﻿

(Elsevier, 2015-06-10)
Dementia impact has received increasing attention of governments and politicians across the globe in recent years. Epidemiological research based Western European populations twenty years ago provided key evidence for ...