Now showing items 6-15 of 15

    • A pooled genome-wide association study of Asperger Syndrome 

      Warrier, Varun; Chakrabarti, Bhismadev; Murphy, Laura; Chan, Allen; Craig, Ian; Mallya, Uma; Lakatošová, Silvia et al. (PLOS, 2015-07-15)
      Asperger Syndrome (AS) is a neurodevelopmental condition characterized by impairments in social interaction and communication, alongside the presence of unusually repetitive, restricted interests and stereotyped behaviour. ...
    • Quantifying and exploring camouflaging in men and women with autism 

      Lai, Meng-Chuan; Lombardo, Michael V.; Ruigrok, Amber N. V.; Chakrabarti, Bhismadev; Auyeung, Bonnie; MRC AIMS Consortium; Szatmari, Peter et al. (SAGE Publications, 2016-11-30)
      Autobiographical descriptions and clinician observations suggest that some individuals with autism, particularly females, ‘camouflage’ their social-communication difficulties, which may require considerable cognitive effort ...
    • Self-referential and social cognition in a case of autism and agenesis of the corpus callosum 

      Lombardo, Michael V; Chakrabarti, Bhismadev; Lai, Meng-Chuan; MRC AIMS Consortium; Baron-Cohen, Simon (2012-11-21)
      Abstract Background While models of autism spectrum conditions (ASC) are emerging at the genetic level of analysis, clear models at higher levels of analysis, such as neuroanatomy, are lacking. Here we examine agenesis of ...
    • Sex and STEM occupation predict Autism-Spectrum Quotient (AQ) scores in half a million people 

      Ruzich, Emily; Allison, Carrie; Chakrabarti, Bhismadev; Smith, Paula; Musto, Henry; Ring, Howard; Baron-Cohen, Simon (PLoS, 2015-10-21)
      This study assesses Autism-Spectrum Quotient (AQ) scores in a ‘big data’ sample collected through the UK Channel 4 television website, following the broadcasting of a medical education program. We examine correlations ...
    • Sex/Gender Differences and Autism: Setting the Scene for Future Research 

      Lai, Meng-Chuan; Lombardo, Michael V.; Auyeung, Bonnie; Chakrabarti, Bhismadev; Baron-Cohen, Simon (Elsevier, 2014-10-16)
      Objective: The relationship between sex/gender differences and autism has attracted a variety of research ranging from clinical and neurobiological to etiological, stimulated by the male bias in autism prevalence. ...
    • The EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation 

      Charman, Tony; Loth, Eva; Tillmann, Julian; Crawley, Daisy; Wooldridge, Caroline; Goyard, David; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism ...
    • The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders 

      Loth, Eva; Charman, Tony; Mason, Luke; Tillmann, Julian; Jones, Emily J H; Wooldridge, Caroline; Ahmad, Jumana et al. (2017-06-23)
      Abstract Background The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of ...
    • Unsupervised data-driven stratification of mentalizing heterogeneity in autism 

      Lombardo, Michael V.; Lai, Meng-Chuan; Auyeung, Bonnie; Holt, Rosemary J.; Allison, Carrie; Smith, Paula; Chakrabarti, Bhismadev et al. (Nature Publishing Group, 2016-10-18)
      Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a ...
    • Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children 

      Tavassoli, Teresa; Auyeung, Bonnie; Murphy, Laura C; Baron-Cohen, Simon; Chakrabarti, Bhismadev (2012-07-06)
      AbstractBackgroundAutism spectrum conditions have a strong genetic component. Atypical sensory sensitivities are one of the core but neglected features of autism spectrum conditions. GABRB3 is a well-characterised candidate ...
    • Variation in the human Cannabinoid Receptor (CNR1) gene modulates gaze duration for happy faces 

      Chakrabarti, Bhismadev; Baron-Cohen, Simon (2011-06-29)
      Abstract Background From an early age, humans look longer at preferred stimuli and also typically look longer at facial expressions of emotion, particularly happy faces. Atypical gaze patterns towards social stimuli are ...