Now showing items 2-10 of 10

    • Genes Required for the Fitness of Salmonella enterica Serovar Typhimurium during Infection of Immunodeficient gp91−/−phox Mice 

      Grant, Andrew James; Oshota, Olusegun; Chaudhuri, Roy R; Mayho, Matthew; Peters, Sarah E; Clare, Simon; Maskell, Duncan John et al. (American Society for Microbiology, 2016-01-19)
      Salmonella enterica causes systemic diseases (typhoid and paratyphoid fever), nontyphoidal septicemia (NTS), and gastroenteritis in humans and other animals worldwide. An important but underrecognized emerging infectious ...
    • Genome-Wide High-Throughput Screening to Investigate Essential Genes Involved in Methicillin-Resistant Staphylococcus aureus Sequence Type 398 Survival 

      Christiansen, Mette T; Kaas, Rolf S; Chaudhuri, Roy R; Holmes, Mark Adrian; Hasman, Henrik; Aarestrup, Frank M (PLoS, 2014-02-12)
      Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) Sequence Type 398 (ST398) is an opportunistic pathogen that is able to colonize and cause disease in several animal species including humans. To ...
    • Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis 

      Weinert, Lucy Anne; Chaudhuri, Roy R; Wang, Jinhong; Peters, Sarah Elizabeth; Corander, Jukka; Jombart, Thibaut; Baig, Abiyad et al. (Nature Publishing Group, 2015-03-31)
      Streptococcus suis causes disease in pigs worldwide and is increasingly implicated in zoonotic disease in East and South-East Asia. To understand the genetic basis of disease in S. suis, we study the genomes of 375 isolates ...
    • "Pathotyping" Multiplex PCR Assay for Haemophilus parasuis: a Tool for Prediction of Virulence. 

      Howell, Kate Joanne; Weinert, Lucy Anne; Peters, Sarah E; Wang, Jinhong; Hernandez-Garcia, Juan; Chaudhuri, Roy R; Luan, Shi-Lu et al. (American Society for Microbiology, 2017-09)
      Haemophilus parasuis is a diverse bacterial species found in the upper respiratory tract of pigs that can also cause Glässer's disease and pneumonia. A previous pan-genome study of H. parasuis identified 48 genes that were ...
    • Transcriptome and proteome analysis of Salmonella enterica serovar Typhimurium systemic infection of wild type and immune-deficient mice. 

      Oshota, Olusegun; Conway, Max; Fookes, Maria; Schreiber, Fernanda; Chaudhuri, Roy R; Yu, Lu; Morgan, Fiona JE et al. (Public Library of Science (PLoS), 2017-01)
      Salmonella enterica are a threat to public health. Current vaccines are not fully effective. The ability to grow in infected tissues within phagocytes is required for S. enterica virulence in systemic disease. As the ...
    • The use of genome wide association methods to investigate pathogenicity, population structure and serovar in Haemophilus parasuis 

      Howell, Kate Joanne; Weinert, Lucy Anne; Chaudhuri, Roy R; Luan, Shi-Lu; Peters, Sarah Elizabeth; Corander, Jukka; Harris, David et al. (2014-12-24)
    • The use of genome wide association methods to investigate pathogenicity, population structure and serovar in Haemophilus parasuis 

      Howell, Kate Joanne; Weinert, Lucy Anne; Chaudhuri, Roy R; Luan, Shi-Lu; Peters, Sarah Elizabeth; Corander, Jukka; Harris, David et al. (BioMed Central, 2014-12-24)
      Background: Haemophilus parasuis is the etiologic agent of Glässer’s disease in pigs and causes devastating losses to the farming industry. Whilst some hyper-virulent isolates have been described, the relationship between ...
    • Whole genome investigation of a divergent clade of the pathogen Streptococcus suis 

      Baig, Abiyad; Weinert, Lucy Anne; Peters, Sarah E; Howell, Kate J; Chaudhuri, Roy R; Wang, Jinhong; Holden, Matthew TG et al. (Frontiers, 2015-11-04)
      Streptococcus suis is a major porcine and zoonotic pathogen responsible for significant economic losses in the pig industry and an increasing number of human cases. Multiple isolates of S. suis show marked genomic diversity. ...
    • Whole Genome Sequencing for Surveillance of Antimicrobial Resistance in Actinobacillus pleuropneumoniae. 

      Bossé, Janine T; Li, Yanwen; Rogers, Jon; Fernandez Crespo, Roberto; Li, Yinghui; Chaudhuri, Roy R; Holden, Matthew TG et al. (2017-01)
      The aim of this study was to evaluate the correlation between antimicrobial resistance (AMR) profiles of 96 clinical isolates of Actinobacillus pleuropneumoniae, an important porcine respiratory pathogen, and the identification ...