Now showing items 1-10 of 10

    • Changes in health in England with analysis by English region and areas of deprivation: findings of the Global Burden of Disease Study 2013 

      Newton, John N; Briggs, Adam DM; Murray, Christopher JL; Dicker, Daniel; Foreman, Kyle J; Wang, Haidong; Naghavi, Mohsen et al. (Elsevier, 2015-09-15)
      Background The Global Burden of Diseases, Injuries, and Risk factors Study 2013 (GBD 2013) integrates knowledge about health and its determinants into a comparable framework to inform health policy. GBD 2013 includes ...
    • Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium 

      Moayyeri, Alireza; Hsu, Yi-Hsiang; Karasik, David; Estrada, Karol; Xiao, Su-Mei; Nielson, Carrie; Srikanth, Priya et al. (Oxford Journals, 2014-01-14)
      Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by x-ray (DXA), may be convenient alternatives for evaluating ...
    • Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Hay, Simon I; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Abdulle, Abdishakur M et al. (2017-09-16)
    • Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals 

      Finucane, Francis M.; Sharp, Stephen J.; Hatunic, Mensud; Sleigh, Alison; De Lucia Rolfe, Ema; Sayer, Avan Aihie; Cooper, Cyrus et al. (2013-5-2)
      Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by ...
    • MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. 

      Harvey, Nicholas C.; Javaid, Kassim; Bishop, Nicholas; Kennedy, Stephen; Papageorghiou, Aris T.; Fraser, Robert; Gandhi, Saurabh V. et al. (2012-02-07)
      Abstract MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR. Background Osteoporosis is a major public ...
    • No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. 

      Scott, Robert; Chu, Audrey Y; Grarup, Niels; Manning, Alisa K; Hivert, Marie-France; Shungin, Dmitry; Tönjes, Anke et al. (2012-05)
    • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 

      Dastani, Zari; Hivert, Marie-France; Timpson, Nicholas; Perry, John Richard; Yuan, Xin; Scott, Robert; Henneman, Peter et al. (2012-01)
    • Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children’s health in India and Sub-Saharan Africa 

      Chandak, Giriraj R; Silver, Matt J; Saffari, Ayden; Lillycrop, Karen A; Shrestha, Smeeta; Sahariah, Sirazul A; Di Gravio, Chiara et al. (2017-10-30)
      Abstract Background Animal studies have shown that nutritional exposures during pregnancy can modify epigenetic marks regulating fetal development and susceptibility to later ...
    • Randomised controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial 

      Finucane, Francis M; Horton, Jessica; Purslow, Lisa R; Savage, David Bousfield; Brage, Soren; Besson, Herve; Horton, Kenneth et al. (2009-06-19)
      Abstract Background While there are compelling observational data confirming that individuals who exercise are healthier, the efficacy of aerobic exercise interventions to reduce metabolic risk and improve insulin sensitivity ...
    • Validation of a maternal questionnaire on correlates of physical activity in preschool children 

      McMinn, Alison M; van, Esther Maria; Harvey, Nicholas C; Cooper, Cyrus; Inskip, Hazel M; Godfrey, Keith M; Griffin, Simon James (2009-12-02)
      Abstract Background Valid measures of physical activity correlates in preschool children are lacking. This study aimed to assess the validity, factor structure and internal consistency of a maternal questionnaire on potential ...