Now showing items 2-10 of 10

    • Genetic determinants of heel bone properties: Genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium 

      Moayyeri, Alireza; Hsu, Yi-Hsiang; Karasik, David; Estrada, Karol; Xiao, Su-Mei; Nielson, Carrie; Srikanth, Priya et al. (Oxford Journals, 2014-01-14)
      Quantitative ultrasound of the heel captures heel bone properties that independently predict fracture risk and, with bone mineral density (BMD) assessed by x-ray (DXA), may be convenient alternatives for evaluating ...
    • Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 

      Hay, Simon I; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M; Abd-Allah, Foad; Abdulle, Abdishakur M et al. (2017-09-16)
      Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy ...
    • Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals 

      Finucane, Francis M.; Sharp, Stephen J.; Hatunic, Mensud; Sleigh, Alison; De Lucia Rolfe, Ema; Sayer, Avan Aihie; Cooper, Cyrus et al. (2013-5-2)
      Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by ...
    • MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. 

      Harvey, Nicholas C.; Javaid, Kassim; Bishop, Nicholas; Kennedy, Stephen; Papageorghiou, Aris T.; Fraser, Robert; Gandhi, Saurabh V. et al. (2012-02-07)
      Abstract MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR. Background Osteoporosis is a major public ...
    • No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels. 

      Scott, Robert; Chu, Audrey Y; Grarup, Niels; Manning, Alisa K; Hivert, Marie-France; Shungin, Dmitry; Tönjes, Anke et al. (2012-05)
    • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 

      Dastani, Zari; Hivert, Marie-France; Timpson, Nicholas; Perry, John Richard; Yuan, Xin; Scott, Robert; Henneman, Peter et al. (2012-01)
    • Protocol for the EMPHASIS study; epigenetic mechanisms linking maternal pre-conceptional nutrition and children’s health in India and Sub-Saharan Africa 

      Chandak, Giriraj R; Silver, Matt J; Saffari, Ayden; Lillycrop, Karen A; Shrestha, Smeeta; Sahariah, Sirazul A; Di Gravio, Chiara et al. (2017-10-30)
      Abstract Background Animal studies have shown that nutritional exposures during pregnancy can modify epigenetic marks regulating fetal development and susceptibility to later ...
    • Randomised controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial 

      Finucane, Francis M; Horton, Jessica; Purslow, Lisa R; Savage, David Bousfield; Brage, Soren; Besson, Herve; Horton, Kenneth et al. (2009-06-19)
      Abstract Background While there are compelling observational data confirming that individuals who exercise are healthier, the efficacy of aerobic exercise interventions to reduce metabolic risk and improve insulin sensitivity ...
    • Validation of a maternal questionnaire on correlates of physical activity in preschool children 

      McMinn, Alison M; van, Esther Maria; Harvey, Nicholas C; Cooper, Cyrus; Inskip, Hazel M; Godfrey, Keith M; Griffin, Simon James (2009-12-02)
      Abstract Background Valid measures of physical activity correlates in preschool children are lacking. This study aimed to assess the validity, factor structure and internal consistency of a maternal questionnaire on potential ...