Now showing items 16-20 of 20

    • PhenoScanner: a database of human genotype-phenotype associations 

      Staley, James R.; Blackshaw, James; Kamat, Mihir A.; Ellis, Steve; Surendran, Praveen; Sun, Benjamin B.; Paul, Dirk S. et al. (Oxford University Press, 2016)
      PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate “phenome scans”, the cross-referencing of genetic variants with many phenotypes, ...
    • Recruitment and representativeness of blood donors in the INTERVAL randomised trial assessing varying inter-donation intervals 

      Moore, Carmel; Bolton, Thomas; Walker, Matthew; Kaptoge, Stephen; Allen, David; Daynes, Michael; Mehenny, Susan et al. (BioMed Central, 2016-09-20)
      Background The interpretation of trial results can be helped by understanding how generalisable they are to the target population for which inferences are intended. INTERVAL, a large pragmatic randomised trial of blood ...
    • The association between psychiatric diagnosis and violent re-offending in adult offenders in the community 

      Grann, Martin; Danesh, John; Fazel, Seena (2008-11-25)
      Abstract Background High rates of repeat offending are common across nations that are socially and culturally different. Although psychiatric disorders are believed to be risk factors for violent reoffending, the available ...
    • Tobacco use and the risk of cardiovascular diseases in developed and developing countries 

      Alexander, Myriam (2013-10-08)
      The association between cigarette smoking and the risk of cardiovascular diseases (CVD) is well established. However, the effect of other, less common, types of smoking on CVD risk, such as pipes and cigars in developed ...
    • Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension 

      Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P.; Manning, Alisa K.; Grarup, Niels et al. (Nature Publishing Group, 2016-09-12)
      High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we ...