Now showing items 22-25 of 25

    • Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease 

      Webb, TR; Erdmann, J; Stirrups, Kathleen Elizabeth; Stitziel, NO; Masca, NGD; Jansen, H; Kanoni, S et al. (Elsevier, 2017-02-21)
      BACKGROUND: Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or ...
    • The association between psychiatric diagnosis and violent re-offending in adult offenders in the community 

      Grann, Martin; Danesh, John; Fazel, Seena (2008-11-25)
      Abstract Background High rates of repeat offending are common across nations that are socially and culturally different. Although psychiatric disorders are believed to be risk factors for violent reoffending, the available ...
    • Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension 

      Surendran, Praveen; Drenos, Fotios; Young, Robin; Warren, Helen; Cook, James P.; Manning, Alisa K.; Grarup, Niels et al. (Nature Publishing Group, 2016-09-12)
      High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we ...
    • Validation of self-administered nasal swabs and postage for the isolation of $\textit{Staphylococcus aureus}$ 

      Harrison, Ewan Michael; Gleadall, Nicholas; Ba, Xiaoliang; Danesh, John; Peacock, Sharon Jayne; Holmes, Mark Adrian (Microbiology Society, 2016-12-01)
      $\textit{Staphylococcus aureus}$ carriers are at higher risk of $\textit{S. aureus}$ infection and are a reservoir for transmission to others. Detection of nasal $\textit{S. aureus}$ carriage is important for both targeted ...