Now showing items 1-5 of 5

    • Data analysis issues for allele-specific expression using Illumina's GoldenGate assay 

      Ritchie, Matthew E; Forrest, Matthew S; Dimas, Antigone S; Daelemans, Caroline; Dermitzakis, Emmanouil T; Deloukas, Panagiotis; Tavare, Simon (2010-05-26)
      Abstract Background High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explore several data sets which make use ...
    • Evaluating the glucose raising effect of established loci via a genetic risk score. 

      Marouli, Eirini; Kanoni, Stavroula; Mamakou, Vasiliki; Hackinger, Sophie; Southam, Lorraine; Prins, Bram Peter; Rentari, Angela et al.
      Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with glucose levels. We tested the hypothesis here whether the cumulative effect of glucose raising SNPs, ...
    • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 

      Scott, Robert A; Scott, Laura J; Mägi, Reedik; Marullo, Letizia; Gaulton, Kyle J; Kaakinen, Marika; Pervjakova, Natalia et al. (American Diabetes Association, 2017-11-01)
      To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum, we conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects of European ...
    • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. 

      Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha et al. (2015-12)
    • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 

      Dastani, Zari; Hivert, Marie-France; Timpson, Nicholas; Perry, John Richard; Yuan, Xin; Scott, Robert; Henneman, Peter et al. (2012-01)