Now showing items 1-5 of 5

    • Data analysis issues for allele-specific expression using Illumina's GoldenGate assay 

      Ritchie, Matthew E; Forrest, Matthew S; Dimas, Antigone S; Daelemans, Caroline; Dermitzakis, Emmanouil T; Deloukas, Panagiotis; Tavare, Simon (2010-05-26)
      Abstract Background High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explore several data sets which make use ...
    • An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 

      Scott, Robert A; Scott, Laura J; Mägi, Reedik; Marullo, Letizia; Gaulton, Kyle J; Kaakinen, Marika; Pervjakova, Natalia et al. (American Diabetes Association, 2017-11-01)
      To characterize type 2 diabetes (T2D)-associated variation across the allele frequency spectrum, we conducted a meta-analysis of genome-wide association data from 26,676 T2D case and 132,532 control subjects of European ...
    • Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. 

      Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; Mahajan, Anubha et al. (2015-12)
    • Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. 

      Dastani, Zari; Hivert, Marie-France; Timpson, Nicholas; Perry, John Richard; Yuan, Xin; Scott, Robert; Henneman, Peter et al. (2012-01)
    • Sequencing and association analysis of the type 1 diabetes - linked region on chromosome 10p12-q11. 

      Nejentsev, Sergey; Smink, Luc J; Smyth, Deborah J; Bailey, Rebecca; Lowe, Christopher Eric; Payne, Felicity; Masters, Jennifer et al. (2007-05-17)
      Background: In an effort to locate susceptibility genes for type I diabetes (TID) several genome-wide linkage scans have been undertaken. A chromosomal region designated IDDM10 retained genome-wide significance in a combined ...