Browsing by Author "Dobson, Christopher M"
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species Iljina, Marija; Hong, Liu; Horrocks, Mathew H; Ludtmann, Marthe H; Choi, Minee L; Hughes, Craig D; Ruggeri, Francesco SGuilliams, TimBuell, Alexander KLee, Ji-EunGandhi, SoniaLee, Steven FBryant, Clare EVendruscolo, MicheleKnowles, Tuomas P JDobson, Christopher MDe Genst, ErwinKlenerman, David et al. (2017-07-03)Abstract Background The aggregation of the protein ɑ-synuclein (ɑS) underlies a range of increasingly common neurodegenerative disorders including Parkinson’s disease. One ...
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis. Hanspal, Maya A; Dobson, Christopher M; Yerbury, Justin J; Kumita, Janet R (Elsevier BV, 2017-07-12)