Now showing items 2-2 of 2

    • A fusion intermediate gp41 immunogen elicits neutralizing antibodies to HIV-1 

      Lai, Rachel PJ; Hock, Miriam; Radzimanowski, Jens; Tonks, Paul Nicholas; Hulsik, David Lutje; Effantin, Gregory; Seilly, David J et al. (American Society for Biochemistry and Molecular Biology, 2014-08-26)
      The membrane proximal external region (MPER) of the HIV-1 Env glycoprotein subunit gp41 is targeted by potent broadly neutralizing antibodies (bnAb) 2F5, 4E10 and 10E8. These antibodies recognize linear epitopes and have ...