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    • Chromosomal instability determines taxane sensitivity - supplementary materials 

      Swanton, Charles; Nicke, Barbara; Schuett, Marion; Eklund, Aron C.; Ng, Charlotte; Li, Qiyuan; Hardcastle, Thomas et al. (2009-04-24)
      Microtubule-stabilizing (MTS) agents, such as taxanes, are important chemotherapeutics with a poorly understood mechanism of action. We identified a set of genes repressed in multiple cell lines in response to MTS agents ...
    • Pro-neural transcription factors as cancer markers 

      Vias, Maria; Massie, Charles E; East, Philip; Scott, Helen; Warren, Anne; Zhou, Zongxiang; Nikitin, Alexander Yu et al. (2008-05-19)
      Abstract Background The aberrant transcription in cancer of genes normally associated with embryonic tissue differentiation at various organ sites may be a hallmark of tumour progression. For example, neuroendocrine ...