Now showing items 3-7 of 7

    • Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independently of obesity 

      Scott, Robert A.; Fall, Tove; Pasko, Dorota; Barker, Adam; Sharp, Stephen J.; Arriola, Larraitz; Balkau, Beverley et al. (American Diabetes Association, 2014-06-19)
      We aimed to validate genetic variants as instruments for insulin resistance and secretion, to characterise their association with intermediate phenotypes, and to investigate their role in T2D risk among normal-weight, ...
    • Dietary Intakes of Individual Flavanols and Flavonols Are Inversely Associated with Incident Type 2 Diabetes in European Populations 

      Zamora-Ros, Raul; Forouhi, Nita G.; Sharp, Stephen J.; Gonzalez, Carlos A.; Buijsse, Brian; Guevara, Marcela; van der Schouw, Yvonne T. et al. (The American Society for Nutrition, 2013-12-24)
      Dietary flavanols and flavonols, flavonoid subclasses, have been recently associated with a lower risk of type 2 diabetes (T2D) in Europe. Even within the same subclass, flavonoids may differ considerably in bioavailability ...
    • Physical Activity and all-cause mortality across levels of general and abdominal adiposity: The European Prospective Investigation into Cancer and Nutrition Study (EPIC) 

      Ekelund, Ulf; Ward, Heather A.; Norat, Teresa; Luan, Jian'an; May, Anne M.; Weiderpass, Elisabete; Sharp, Stephen S. et al. (American Society for Nutrition, 2015-01-14)
      Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number of deaths reduced by eliminating physical inactivity compared with overall ...
    • The association of education with body mass index and waist circumference in the EPIC-PANACEA study 

      Hermann, Silke; Rohrmann, Sabine; Linseisen, Jakob; May, Anne M.; Kunst, Anton; Besson, Herve; Romaguera, Dora et al. (2011-03-17)
      Abstract Background To examine the association of education with body mass index (BMI) and waist circumference (WC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Method This study included ...
    • The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk 

      Campa, Daniele; Husing, Anika; McKay, James D.; Sinilnikova, Olga M.; Vogel, Ulla; Tjonneland, Anne; Overvad, Kim et al. (2010-10-18)
      Abstract Background The single nucleotide polymorphism rs7566605, located in the promoter of the INSIG2 gene, has been the subject of a strong scientific effort aimed to elucidate its possible association with body mass ...