Now showing items 3-5 of 5

    • Chromatin signatures at Notch regulated enhancers reveal large-scale changes in H3K56ac upon activation 

      Skalska, Lenka; Stojnic, Robert; Li, Jinghua; Fischer, Bettina; Cerda-Moya, Gustavo; Sakai, Hiroshi; Tajbakhsh, Shahragim et al. (Wiley, 2015-06-10)
      The conserved Notch pathway functions in diverse developmental and disease-related processes, requiring mechanisms to ensure appropriate target-selection and gene activation in each context. To investigate the influence ...
    • SimArray: a user-friendly and user-configurable microarray design tool 

      Auburn, Richard P.; Russell, Roslin; Fischer, Bettina; Meadows, Lisa A.; Sevillano Matilla, Santiago; Russell, Steven R. (2006-03-01)
      Abstract Background Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Regardless of the intended application, ...
    • The impact of quantitative optimization of hybridization conditions on gene expression analysis 

      Sykacek, Peter; Kreil, David P.; Meadows, Lisa A.; Auburn, Richard P.; Fischer, Bettina; Russell, Steven R.; Micklem, Gos (2011-03-14)
      Abstract Background With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studies. While probe-design is a major ...