Browsing by Author "Flesch-Janys, Dieter"
Now showing items 9-17 of 17
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Genetic variation in the immunosuppression pathway genes and breast cancer: a pooled analysis of 42,510 cases and 40,577 controls from the Breast
Lei, Jieping; Rudolph, Anja; Moysich, Kirsten B.; Behrens, Sabine; Goode, Ellen L.; Bolla, Manjeet K.; Dennis, JoeDunning, Alison M.Easton, Douglas F.Wang, QinBenitez, JavierHopper, John L.Southey, Melissa C.Schmidt, Marjanka K.Broeks, AnnegienFasching, Peter A.Haeberle, LotharPeto, Juliandos-Santos-Silva, IsabelSawyer, Elinor J.Tomlinson, IanBurwinkel, BarbaraMarmé, FrederikGuénel, PascalTruong, ThérèseBojesen, Stig E.Flyger, HenrikNielsen, Sune F.Nordestgaard, Børge G.González-Neira, AnnaMenéndez, PrimitivaAnton-Culver, HodaNeuhausen, Susan L.Brenner, HermannArndt, VolkerMeindl, AlfonsSchmutzler, Rita K.Brauch, HiltrudHamann, UteNevanlinna, HeliFagerholm, RainerDörk, ThiloBogdanova, Natalia V.Mannermaa, ArtoHartikainen, Jaana M.Australian Ovarian Study GroupkConFab Investigatorsvan Dijck, LaurienSmeets, AnnFlesch-Janys, DieterEilber, UrsulaRadice, PaoloPeterlongo, PaoloCouch, Fergus J.Hallberg, EmilyGiles, Graham G.Milne, Roger L.Haiman, Christopher A.Schumacher, FredrickSimard, JacquesGoldberg, Mark S.Kristensen, VesselaBorresen-Dale, Anne-LiseZheng, WeiBeeghly-Fadiel, AliciaWinqvist, RobertGrip, MerviAndrulis, Irene L.Glendon, GordGarcía-Closas, MontserratFigueroa, JonineCzene, KamilaBrand, Judith S.Darabi, HatefEriksson, MikaelHall, PerLi, JingmeiCox, AngelaCross, Simon S.Pharoah, Paul D. P.Shah, MitulKabisch, MariaTorres, DianaJakubowska, AnnaLubinski, JanAdemuyiwa, FolusoAmbrosone, Christine B.Swerdlow, AnthonyJones, MichaelChang-Claude, Jenny et al. (Springer, 2015-11-30)Immunosuppression plays a pivotal role in assisting tumors to evade immune destruction and promoting tumor development. We hypothesized that genetic variation in the immunosuppression pathway genes may be implicated in ... -
Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
Guo, Yan; Andersen, Shaneda Warren; Shu, Xiao-Ou; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Qin; Garcia-Closas, MontserratMilne, Roger L.Schmidt, Marjanka K.Chang-Claude, JennyDunning, AllisonBojesen, Stig E.Ahsan, HabibulAittomäki, KristiinaAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerBeckmann, Matthias W.Beeghly-Fadiel, AliciaBenitez, JavierBogdanova, Natalia V.Bonanni, BernardoBørresen-Dale, Anne-LiseBrand, JudithBrauch, HiltrudBrenner, HermannBrüning, ThomasBurwinkel, BarbaraCasey, GrahamChenevix-Trench, GeorgiaCouch, Fergus J.Cox, AngelaCross, Simon S.Czene, KamilaDevilee, PeterDörk, ThiloDumont, MartineFasching, Peter A.Figueroa, JonineFlesch-Janys, DieterFletcher, OliviaFlyger, HenrikFostira, FlorentiaGammon, MarilieGiles, Graham G.Guénel, PascalHaiman, Christopher A.Hamann, UteHooning, Maartje J.Hopper, John L.Jakubowska, AnnaJasmine, FarzanaJenkins, MarkJohn, Esther M.Johnson, NicholaJones, Michael E.Kabisch, MariaKibriya, MuhammadKnight, Julia A.Koppert, Linetta B.Kosma, Veli-MattiKristensen, VesselaLe Marchand, LoicLee, EunjungLi, JingmeiLindblom, AnnikaLuben, RobertLubinski, JanMalone, Kathi E.Mannermaa, ArtoMargolin, SaraMarme, FrederikMcLean, CatrionaMeijers-Heijboer, HanneMeindl, AlfonsNeuhausen, Susan L.Nevanlinna, HeliNeven, PatrickOlson, Janet E.Perez, Jose I. A.Perkins, BarbaraPeterlongo, PaoloPhillips, Kelly-AnnePylkäs, KatriRudolph, AnjaSantella, ReginaSawyer, Elinor J.Schmutzler, Rita K.Seynaeve, CarolineShah, MitulShrubsole, Martha J.Southey, Melissa C.Swerdlow, Anthony J.Toland, Amanda E.Tomlinson, IanTorres, DianaTruong, ThérèseUrsin, GiskeVan Der Luijt, Rob B.Verhoef, SennoWhittemore, Alice S.Winqvist, RobertZhao, HuiZhao, ShilinHall, PerSimard, JacquesKraft, PeterPharoah, PaulHunter, DavidEaston, Douglas F.Zheng, Wei et al. (Public Library of Science, 2016-08-23)$\textbf{Background}$ Observational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal ... -
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Michailidou, Kyriaki; Beesley, Jonathan; Lindstrom, Sara; Canisius, Sander; Dennis, Joe; Lush, Michael J.; Maranian, Mel J.Bolla, Manjeet K.Wang, QinShah, MitulPerkins, Barbara J.Czene, KamilaEriksson, MikaelDarabi, HatefBrand, Judith S.Bojesen, Stig E.Nordestgaard, Borge G.Flyger, HenrikNielsen, Sune F.Rahman, NazneenTurnbull, ClareBOCSFletcher, OliviaPeto, JulianGibson, Lornados-Santos-Silva, IsabelChang-Claude, JennyFlesch-Janys, DieterRudolph, AnjaEilber, UrsulaBehrens, SabineNevanlinna, HeliMuranen, Taru A.Aittomaki, KristiinaBlomqvist, CarlKhan, SofiaAaltonen, KirsimariAhsan, HabibulKibriya, Muhammad G.Whittemore, Alice S.John, Esther M.Malone, Kathleen E.Gammon, Marilie D.Santella, Regina M.Ursin, GiskeMakalic, EnesSchmidt, Daniel F.Casey, GrahamHunter, David J.Gapstur, Susan M.Gaudet, Mia M.Diver, W. RyanHaiman, Christopher A.Schumacher, FredrickHenderson, Brian E.Le Marchand, LoicBerg, Christine D.Chanock, Stephen J.Figueroa, JonineHoover, Robert N.Lambrechts, DietherNeven, PatrickWildiers, Hansvan Limbergen, ErikSchmidt, Marjanka K.Broeks, AnnegienVerhoef, SennoCornelissen, StenCouch, Fergus J.Olson, Janet E.Hallberg, EmilyVachon, CelineWaisfisz, QuintenMeijers-Heijboer, HanneAdank, Muriel A.van der Luijt, Rob B.Li, JingmeiLiu, JianjunHumphreys, KeithKang, DaeheeChoi, Ji-YeobPark, Sue K.Yoo, Keun-YoungMatsuo, KeitaroIto, HidemiIwata, HirojiTajima, KazuoGuenel, PascalTruong, ThereseMulot, ClaireSanchez, MarieBurwinkel, BarbaraMarme, FrederikSurowy, HaraldSohn, ChristofWu, Anna H.Tseng, Chiu-chenVan Den Berg, DavidStram, Daniel O.Gonzalez-Neira, AnnaBenitez, JavierZamora, M. PilarPerez, Jose Ignacio AriasShu, Xiao-OuLu, WeiGao, Yu-TangCai, HuiCox, AngelaCross, Simon S.Reed, Malcolm W. R.Andrulis, Irene L.Knight, Julia A.Glendon, GordMulligan, Anna MarieSawyer, Elinor J.Tomlinson, IanKerin, Michael J.Miller, NicolakConFab InvestigatorsAOCS GroupLindblom, AnnikaMargolin, SaraTeo, Soo HwangYip, Cheng HarTaib, Nur Aishah MohdTan, Gie-HooiHooning, Maartje J.Hollestelle, AntoinetteMartens, John W. M.Collee, J. MargrietBlot, WilliamSignorello, Lisa B.Cai, QiuyinHopper, John L.Southey, Melissa C.Tsimiklis, HelenApicella, CarmelShen, Chen-YangHsiung, Chia-NiWu, Pei-EiHou, Ming-FengKristensen, Vessela N.Nord, SiljeAlnaes, Grethe I. GrenakerNBCSGiles, Graham G.Milne, Roger L.McLean, CatrionaCanzian, FedericoTrichopoulos, DimitriosPeeters, PetraLund, EilivSund, MalinKhaw, Kay-TeeGunter, Marc J.Palli, DomenicoMortensen, Lotte MaxildDossus, LaureHuerta, Jose-MariaMeindl, AlfonsSchmutzler, Rita K.Sutter, ChristianYang, RongxiMuir, KennethLophatananon, ArtitayaStewart-Brown, SarahSiriwanarangsan, PornthepHartman, MikaelMiao, HuiChia, Kee SengChan, Ching WanFasching, Peter A.Hein, AlexanderBeckmann, Matthias W.Haeberle, LotharBrenner, HermannDieffenbach, Aida KarinaArndt, VolkerStegmaier, ChristaAshworth, AlanOrr, NickSchoemaker, Minouk J.Swerdlow, Anthony J.Brinton, LouiseGarcia-Closas, MontserratZheng, WeiHalverson, Sandra L.Shrubsole, MarthaLong, JirongGoldberg, Mark S.Labreche, FranceDumont, MartineWinqvist, RobertPylkas, KatriJukkola-Vuorinen, ArjaGrip, MerviBrauch, HiltrudHamann, UteBruning, ThomasGENICA NetworkRadice, PaoloPeterlongo, PaoloManoukian, SiranoushBernard, LorisBogdanova, Natalia V.Dork, ThiloMannermaa, ArtoKataja, VesaKosma, Veli-MattiHartikainen, Jaana M.Devilee, PeterTollenaar, Robert A. E. M.Seynaeve, CarolineVan Asperen, Christi J.Jakubowska, AnnaLubinski, JanJaworska, KatarzynaHuzarski, TomaszSangrajrang, SuleepornGaborieau, ValerieBrennan, PaulMcKay, JamesSlager, SusanToland, Amanda E.Ambrosone, Christine B.Yannoukakos, DrakoulisKabisch, MariaTorres, DianaNeuhausen, Susan L.Anton-Culver, HodaLuccarini, CraigBaynes, CarolineAhmed, ShahanaHealey, Catherine S.Tessier, Daniel C.Vincent, DanielBacot, FrancoisPita, GuillermoAlonso, M. RosarioAlvarez, NuriaHerrero, DanielSimard, JacquesPharoah, Paul D. P.Kraft, PeterDunning, Alison M.Chenevix-Trench, GeorgiaHall, PerEaston, Douglas F. et al. (NPG, 2015-03-09)Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining ~14% of the familial risk of the disease. To identify new ... -
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
Kar, Siddhartha P.; Beesley, Jonathan; Amin Al Olama, Ali; Michailidou, Kyriaki; Tyrer, Jonathan; Kote-Jarai, ZSofia; Lawrenson, KateLindstrom, SaraRamus, Susan J.Thompson, Deborah J.ABCTB InvestigatorsKibel, Adam S.Dansonka-Mieszkowska, AgnieszkaMichael, AgnieszkaDieffenbach, Aida K.Gentry-Maharaj, AleksandraWhittemore, Alice S.Wolk, AlicjaMonteiro, AlvaroPeixoto, AnaKierzek, AndrzejCox, AngelaRudolph, AnjaGonzalez-Neira, AnnaWu, Anna H.Lindblom, AnnikaSwerdlow, AnthonyAOCS Study Group & Australian Cancer Study (Ovarian Cancer)APCB BioResourceZiogas, ArgyriosEkici, Arif B.Burwinkel, BarbaraKarlan, Beth Y.Nordestgaard, Børge G.Blomqvist, CarlPhelan, CatherineMcLean, CatrionaPearce, Celeste LeighVachon, CelineCybulski, CezarySlavov, ChavdarStegmaier, ChristaMaier, ChristianeAmbrosone, Christine B.Høgdall, Claus K.Teerlink, Craig C.Kang, DaeheeTessier, Daniel C.Schaid, Daniel J.Stram, Daniel O.Cramer, Daniel W.Neal, David E.Eccles, DianaFlesch-Janys, DieterEdwards, Digna R. VelezWokozorczyk, DominikaLevine, Douglas A.Yannoukakos, DrakoulisSawyer, Elinor J.Bandera, Elisa V.Poole, Elizabeth M.Goode, Ellen L.Khusnutdinova, ElzaHøgdall, EstridSong, FengjuBruinsma, FionaHeitz, FlorianModugno, FrancesmaryHamdy, Freddie C.Wiklund, FredrikGiles, Graham G.Olsson, HåkanWildiers, HansUlmer, Hans-UlrichPandha, HardevRisch, Harvey A.Darabi, HatefSalvesen, Helga B.Nevanlinna, HeliGronberg, HenrikBrenner, HermannBrauch, HiltrudAnton-Culver, HodaSong, HonglinLim, Hui-YiMcNeish, IainCampbell, IanVergote, IgnaceGronwald, JacekLubiński, JanStanford, Janet L.Benítez, JavierDoherty, Jennifer A.Permuth, Jennifer B.Chang-Claude, JennyDonovan, Jenny L.Dennis, JoeSchildkraut, Joellen M.Schleutker, JohannaHopper, John L.Kupryjanczyk, JolantaPark, Jong Y.Figueroa, JonineClements, Judith A.Knight, Julia A.Peto, JulianCunningham, Julie M.Pow-Sang, JulioBatra, JyotsnaCzene, KamilaLu, Karen H.Herkommer, KathleenKhaw, Kay-TeekConFab InvestigatorsMatsuo, KeitaroMuir, KennethOffitt, KennethChen, KexinMoysich, Kirsten B.Aittomäki, KristiinaOdunsi, KunleKiemeney, Lambertus A.Massuger, Leon F.A.G.Fitzgerald, Liesel M.Cook, Linda S.Cannon-Albright, LisaHooning, Maartje J.Pike, Malcolm C.Bolla, Manjeet K.Luedeke, ManuelTeixeira, Manuel R.Goodman, Marc T.Schmidt, Marjanka K.Riggan, MarjorieAly, MarkusRossing, Mary AnneBeckmann, Matthias W.Moisse, MatthieuSanderson, MaureenSouthey, Melissa C.Jones, MichaelLush, MichaelHildebrandt, Michelle A.T.Hou, Ming-FengSchoemaker, Minouk J.Garcia-Closas, MontserratBogdanova, NataliaRahman, NazneenNBCS InvestigatorsLe, Nhu D.Orr, NickWentzensen, NicolasPashayan, NoraPeterlongo, PaoloGuénel, PascalBrennan, PaulPaulo, PaulaWebb, Penelope M.Broberg, PerFasching, Peter A.Devilee, PeterWang, QinCai, QiuyinLi, QiyuanKaneva, RadkaButzow, RalfKopperud, Reidun KristinSchmutzler, Rita K.Stephenson, Robert A.MacInnis, Robert J.Hoover, Robert N.Winqvist, RobertNess, RobertaMilne, Roger L.Travis, Ruth C.Benlloch, SaraOlson, Sara H.McDonnell, Shannon K.Tworoger, Shelley S.Maia, SofiaBerndt, SonjaLee, Soo ChinTeo, Soo-HwangThibodeau, Stephen N.Bojesen, Stig E.Gapstur, Susan M.Kjær, Susanne KrügerPejovic, TanjaTammela, Teuvo L.J.the GENICA Networkthe PRACTICAL consortiumDörk, ThiloBrüning, ThomasWahlfors, TiinaKey, Tim J.Edwards, Todd L.Menon, UshaHamann, UteMitev, VanioKosma, Veli-MattiSetiawan, Veronica WendyKristensen, VesselaArndt, VolkerVogel, WaltherZheng, WeiSieh, WeivaBlot, William J.Kluzniak, WojciechShu, Xiao-OuGao, Yu-TangSchumacher, FredrickFreedman, Matthew L.Berchuck, AndrewDunning, Alison M.Simard, JacquesHaiman, Christopher A.Spurdle, AmandaSellers, Thomas A.Hunter, David J.Henderson, Brian E.Kraft, PeterChanock, Stephen J.Couch, Fergus J.Hall, PerGayther, Simon A.Easton, Douglas F.Chenevix-Trench, GeorgiaEeles, RosalindPharoah, Paul D.P.Lambrechts, Diether et al. (American Association for Cancer Research, 2016-07-17)Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic basis, but this has not been investigated systematically by genome-wide association (GWA) studies. Meta-analyses combining the largest ... -
Identification and characterisation of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
Lin, Wei-Yu; Camp, Nicola J.; Ghoussaini, Maya; Beesley, Jonathan; Michailidou, Kyriaki; Hopper, John L.; Apicella, CarmelStone, JenniferSchmidt, Marjanka K.Broeks, AnnegienVan't Veer, Laura J.Rutgers, Emiel J. Th.Muir, KennethLophatananon, ArtitayaStewart-Brown, SarahSiriwanarangsan, PornthepFasching, Peter A.Haeberle, LotharEkici, Arif B.Beckmann, Matthias W.Peto, Juliandos-Santos-Silva, IsabelFletcher, OliviaJohnson, NicholaBolla, Manjeet K.Wang, QinDennis, JoeSawyer, Elinor J.Cheng, TimothyTomlinson, IanKerin, Michael J.Miller, NicolaMarmé, FrederikSurowy, Harald M.Burwinkel, BarbaraGuénel, PascalTruong, ThérèseMenegaux, FlorenceMulot, ClaireBojesen, Stig E.Nordestgaard, Børge G.Nielsen, Sune F.Flyger, HenrikBenitez, JavierZamora, M. PilarPerez, Jose Ignacio AriasMenéndez, PrimitivaGonzález-Neira, AnnaPita, GuillermoAlonso, M. RosarioÁlvarez, NuriaHerrero, DanielAnton-Culver, HodaBrenner, HermannDieffenbach, Aida KarinaArndt, VolkerStegmaier, ChristaMeindl, AlfonsLichtner, PeterSchmutzler, Rita K.Müller-Myhsok, BertramBrauch, HiltrudBrüning, ThomasKo, Yon-DschunGENICA NetworkTessier, Daniel C.Vincent, DanielBacot, FrancoisNevanlinna, HeliAittomäki, KristiinaBlomqvist, CarlKhan, SofiaMatsuo, KeitaroIto, HidemiIwata, HirojiHorio, AkiyoBogdanova, Natalia V.Antonenkova, Natalia N.Dörk, ThiloLindblom, AnnikaMargolin, SaraMannermaa, ArtoKataja, VesaKosma, Veli-MattiHartikainen, Jaana M.kConFab InvestigatorsAustralian Ovarian Cancer Study GroupWu, Anna H.Tseng, Chiu-chenBerg, David Van DenStram, Daniel O.Neven, PatrickWauters, ElsWildiers, HansLambrechts, DietherChang-Claude, JennyRudolph, AnjaSeibold, PetraFlesch-Janys, DieterRadice, PaoloPeterlongo, PaoloManoukian, SiranoushBonanni, BernardoCouch, Fergus J.Wang, XianshuVachon, CelinePurrington, KristenGiles, Graham G.Milne, RogerMcLean, CatrionaHaiman, Christopher A.Henderson, Brian E.Schumacher, FredrickLe Marchand, LoicSimard, JacquesGoldberg, Mark S.Labrèche, FranceDumont, MartineTeo, Soo HwangYip, Cheng HarHassan, NorhashimahVithana, Eranga NishanthieKristensen, VesselaZheng, WeiDeming-Halverson, SandraShrubsole, MarthaLong, JirongWinqvist, RobertPylkäs, KatriJukkola-Vuorinen, ArjaKauppila, SailaAndrulis, Irene L.Knight, Julia A.Glendon, GordTchatchou, SandrineDevilee, PeterTollenaar, Robert A. E. M.Seynaeve, CarolineAsperen, Christi J. VanGarcía-Closas, MontserratFigueroa, JonineLissowska, JolantaBrinton, LouiseCzene, KamilaDarabi, HatefEriksson, MikaelBrand, Judith S.Hooning, Maartje J.Hollestelle, AntoinetteOuweland, Ans M. W. van denJager, AgnesLi, JingmeiLiu, JianjunHumphreys, KeithShu, Xiao-OuLu, WeiGao, Yu-TangCai, HuiCross, Simon S.Reed, Malcolm W. R.Blot, WilliamSignorello, Lisa B.Cai, QiuyinPharoah, Paul D. P.Perkins, BarbaraShah, MitulBlows, Fiona M.Kang, DaeheeYoo, Keun-YoungNoh, Dong-YoungHartman, MikaelMiao, HuiChia, Kee SengPutti, Thomas ChoudaryHamann, UteLuccarini, CraigBaynes, CarolineAhmed, ShahanaMaranian, MelHealey, Catherine S.Jakubowska, AnnaLubinski, JanJaworska-Bieniek, KatarzynaDurda, KatarzynaSangrajrang, SuleepornGaborieau, ValerieBrennan, PaulMcKay, JamesSlager, SusanToland, Amanda E.Yannoukakos, DrakoulisShen, Chen-YangHsiung, Chia-NiWu, Pei-EiDing, Shian-lingAshworth, AlanJones, MichaelOrr, NickSwerdlow, Anthony J.Tsimiklis, HelenMakalic, EnesSchmidt, Daniel F.Bui, Quang M.Chanock, Stephen J.Hunter, David J.Hein, RebeccaDahmen, NorbertBeckmann, LarsAaltonen, KirsimariMuranen, Taru A.Heikkinen, TuomasIrwanto, AstridRahman, NazneenTurnbull, ClareBreast and Ovarian Cancer Susceptibility StudyWaisfisz, QuintenMeijers-Heijboer, Hanne E. J.Adank, Muriel A.Luijt, Rob B. van derHall, PerChenevix-Trench, GeorgiaDunning, Alison M.Easton, Douglas F.Cox, Angela et al. (Oxford University Press, 2014-08-28)Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility we carried out dense genotyping of this region ... -
Identification of four novel susceptibility loci for estrogen receptor negative breast cancer
Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, CurtisHallberg, EmilyAgata, SimonaAhsan, HabibulAittomäki, KristiinaAmbrosone, ChristineAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerArun, Banu K.Arver, BritaBarile, MonicaBarkardottir, Rosa B.Barrowdale, DanielBeckmann, LarsBeckmann, Matthias W.Benitez, JavierBlank, Stephanie V.Blomqvist, CarlBogdanova, Natalia V.Bojesen, Stig E.Bolla, Manjeet K.Bonanni, BernardoBrauch, HiltrudBrenner, HermannBurwinkel, BarbaraBuys, Saundra S.Caldes, TrinidadCaligo, Maria A.Canzian, FedericoCarpenter, JaneChang-Claude, JennyChanock, Stephen J.Chung, Wendy K.Claes, Kathleen B. M.Cox, AngelaCross, Simon S.Cunningham, Julie M.Czene, KamilaDaly, Mary B.Damiola, FrancescaDarabi, Hatefde la Hoya, MiguelDevilee, PeterDiez, OrlandDing, Yuan C.Dolcetti, RiccardoDomchek, Susan M.Dorfling, Cecilia M.dos-Santos-Silva, IsabelDumont, MartineDunning, Alison M.Eccles, Diana M.Ehrencrona, HansEkici, Arif B.Eliassen, HeatherEllis, SteveFasching, Peter A.Figueroa, JonineFlesch-Janys, DieterFörsti, AstaFostira, FlorentiaFoulkes, William D.Friebel, TaraFriedman, EitanFrost, DebraGabrielson, MarikeGammon, Marilie D.Ganz, Patricia A.Gapstur, Susan M.Garber, JudyGaudet, Mia M.Gayther, Simon A.Gerdes, Anne-MarieGhoussaini, MayaGiles, Graham G.Glendon, GordGodwin, Andrew K.Goldberg, Mark S.Goldgar, David E.González-Neira, AnnaGreene, Mark H.Gronwald, JacekGuénel, PascalGunter, MarcHaeberle, LotharHaiman, Christopher A.Hamann, UteHansen, Thomas V. O.Hart, StevenHealey, SueHeikkinen, TuomasHenderson, Brian E.Herzog, JosefHogervorst, Frans B. L.Hollestelle, AntoinetteHooning, Maartje J.Hoover, Robert N.Hopper, John L.Humphreys, KeithHunter, David J.Huzarski, TomaszImyanitov, Evgeny N.Isaacs, ClaudineJakubowska, AnnaJames, PaulJanavicius, RamunasJensen, Uffe BirkJohn, Esther M.Jones, MichaelKabisch, MariaKar, SiddarthaKarlan, Beth Y.Khan, SofiaKhaw, Kay-TeeKibriya, Muhammad G.Knight, Julia A.Ko, Yon-DschunKonstantopoulou, IreneKosma, Veli-MattiKristensen, VesselaKwong, AvaLaitman, YaelLambrechts, DietherLazaro, ConxiLee, EunjungMarchand, Loic LeLester, JennyLindblom, AnnikaLindor, NoralaneLindstrom, SaraLiu, JianjunLong, JirongLubinski, JanMai, Phuong L.Makalic, EnesMalone, Kathleen E.Mannermaa, ArtoManoukian, SiranoushMargolin, SaraMarme, FrederikMartens, John W. M.McGuffog, LesleyMeindl, AlfonsMiller, AustinMilne, Roger L.Miron, PenelopeMontagna, MarcoMazoyer, SylvieMulligan, Anna M.Muranen, Taru A.Nathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNordestgaard, Børge G.Nussbaum, Robert L.Offit, KennethOlah, EdithOlopade, Olufunmilayo I.Olson, Janet E.Osorio, AnaPark, Sue K.Peeters, Petra H.Peissel, BernardPeterlongo, PaoloPeto, JulianPhelan, Catherine M.Pilarski, RobertPoppe, BrucePylkäs, KatriRadice, PaoloRahman, NazneenRantala, JohannaRappaport, ChristineRennert, GadRichardson, AndreaRobson, MarkRomieu, IsabelleRudolph, AnjaRutgers, Emiel J.Sanchez, Maria-JoseSantella, Regina M.Sawyer, Elinor J.Schmidt, Daniel F.Schmidt, Marjanka K.Schmutzler, Rita K.Schumacher, FredrickScott, RodneySenter, LeighaSharma, PriyankaSimard, JacquesSinger, Christian F.Sinilnikova, Olga M.Soucy, PennySouthey, MelissaSteinemann, DorisStenmark-Askmalm, MarieStoppa-Lyonnet, DominiqueSwerdlow, AnthonySzabo, Csilla I.Tamimi, RullaTapper, WilliamTeixeira, Manuel R.Teo, Soo-HwangTerry, Mary B.Thomassen, MadsThompson, DeborahTihomirova, LaimaToland, Amanda E.Tollenaar, Robert A. E. M.Tomlinson, IanTruong, ThérèseTsimiklis, HelenTeulé, AlexTumino, RosarioTung, NadineTurnbull, ClareUrsin, Giskivan Deurzen, Carolien H. M.van Rensburg, Elizabeth J.Varon-Mateeva, RaymondaWang, ZhaomingWang-Gohrke, ShanWeiderpass, ElisabeteWeitzel, Jeffrey N.Whittemore, AliceWildiers, HansWinqvist, RobertYang, Xiaohong R.Yannoukakos, DrakoulisYao, SongZamora, M. PilarZheng, WeiHall, PerKraft, PeterVachon, CelineSlager, SusanChenevix-Trench, GeorgiaPharoah, Paul D. P.Monteiro, Alvaro A. N.García-Closas, MontserratEaston, Douglas F.Antoniou, Antonis C. et al. (Nature Publishing Group, 2016)Common variants in 94 loci have been associated with breast cancer including 15 loci with genome wide significant associations (P<5x10-8) with estrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer ... -
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna; Olswold, CurtisHallberg, EmilyAgata, SimonaAhsan, HabibulAittomäki, KristiinaAmbrosone, ChristineAndrulis, Irene L.Anton-Culver, HodaArndt, VolkerArun, Banu K.Arver, BritaBarile, MonicaBarkardottir, Rosa B.Barrowdale, DanielBeckmann, LarsBeckmann, Matthias W.Benitez, JavierBlank, Stephanie V.Blomqvist, CarlBogdanova, Natalia V.Bojesen, Stig E.Bolla, Manjeet K.Bonanni, BernardoBrauch, HiltrudBrenner, HermannBurwinkel, BarbaraBuys, Saundra S.Caldes, TrinidadCaligo, Maria A.Canzian, FedericoCarpenter, JaneChang-Claude, JennyChanock, Stephen J.Chung, Wendy K.Claes, Kathleen B. M.Cox, AngelaCross, Simon S.Cunningham, Julie M.Czene, KamilaDaly, Mary B.Damiola, FrancescaDarabi, Hatefde la Hoya, MiguelDevilee, PeterDiez, OrlandDing, Yuan C.Dolcetti, RiccardoDomchek, Susan M.Dorfling, Cecilia M.dos-Santos-Silva, IsabelDumont, MartineDunning, Alison M.Eccles, Diana M.Ehrencrona, HansEkici, Arif B.Eliassen, HeatherEllis, SteveFasching, Peter A.Figueroa, JonineFlesch-Janys, DieterFörsti, AstaFostira, FlorentiaFoulkes, William D.Friebel, TaraFriedman, EitanFrost, DebraGabrielson, MarikeGammon, Marilie D.Ganz, Patricia A.Gapstur, Susan M.Garber, JudyGaudet, Mia M.Gayther, Simon A.Gerdes, Anne-MarieGhoussaini, MayaGiles, Graham G.Glendon, GordGodwin, Andrew K.Goldberg, Mark S.Goldgar, David E.González-Neira, AnnaGreene, Mark H.Gronwald, JacekGuénel, PascalGunter, MarcHaeberle, LotharHaiman, Christopher A.Hamann, UteHansen, Thomas V. O.Hart, StevenHealey, SueHeikkinen, TuomasHenderson, Brian E.Herzog, JosefHogervorst, Frans B. L.Hollestelle, AntoinetteHooning, Maartje J.Hoover, Robert N.Hopper, John L.Humphreys, KeithHunter, David J.Huzarski, TomaszImyanitov, Evgeny N.Isaacs, ClaudineJakubowska, AnnaJames, PaulJanavicius, RamunasJensen, Uffe BirkJohn, Esther M.Jones, MichaelKabisch, MariaKar, SiddharthaKarlan, Beth Y.Khan, SofiaKhaw, Kay-TeeKibriya, Muhammad G.Knight, Julia A.Ko, Yon-DschunKonstantopoulou, IreneKosma, Veli-MattiKristensen, VesselaKwong, AvaLaitman, YaelLambrechts, DietherLazaro, ConxiLee, EunjungLe Marchand, LoicLester, JennyLindblom, AnnikaLindor, NoralaneLindstrom, SaraLiu, JianjunLong, JirongLubinski, JanMai, Phuong L.Makalic, EnesMalone, Kathleen E.Mannermaa, ArtoManoukian, SiranoushMargolin, SaraMarme, FrederikMartens, John W. M.McGuffog, LesleyMeindl, AlfonsMiller, AustinMilne, Roger L.Miron, PenelopeMontagna, MarcoMazoyer, SylvieMulligan, Anna M.Muranen, Taru A.Nathanson, Katherine L.Neuhausen, Susan L.Nevanlinna, HeliNordestgaard, Børge G.Nussbaum, Robert L.Offit, KennethOlah, EdithOlopade, Olufunmilayo I.Olson, Janet E.Osorio, AnaPark, Sue K.Peeters, Petra H.Peissel, BernardPeterlongo, PaoloPeto, JulianPhelan, Catherine M.Pilarski, RobertPoppe, BrucePylkäs, KatriRadice, PaoloRahman, NazneenRantala, JohannaRappaport, ChristineRennert, GadRichardson, AndreaRobson, MarkRomieu, IsabelleRudolph, AnjaRutgers, Emiel J.Sanchez, Maria-JoseSantella, Regina M.Sawyer, Elinor J.Schmidt, Daniel F.Schmidt, Marjanka K.Schmutzler, Rita K.Schumacher, FredrickScott, RodneySenter, LeighaSharma, PriyankaSimard, JacquesSinger, Christian F.Sinilnikova, Olga M.Soucy, PennySouthey, MelissaSteinemann, DorisStenmark-Askmalm, MarieStoppa-Lyonnet, DominiqueSwerdlow, AnthonySzabo, Csilla I.Tamimi, RullaTapper, WilliamTeixeira, Manuel R.Teo, Soo-HwangTerry, Mary B.Thomassen, MadsThompson, DeborahTihomirova, LaimaToland, Amanda E.Tollenaar, Robert A. E. M.Tomlinson, IanTruong, ThérèseTsimiklis, HelenTeulé, AlexTumino, RosarioTung, NadineTurnbull, ClareUrsin, Giskivan Deurzen, Carolien H. M.van Rensburg, Elizabeth J.Varon-Mateeva, RaymondaWang, ZhaomingWang-Gohrke, ShanWeiderpass, ElisabeteWeitzel, Jeffrey N.Whittemore, AliceWildiers, HansWinqvist, RobertYang, Xiaohong R.Yannoukakos, DrakoulisYao, SongZamora, M. PilarZheng, WeiHall, PerKraft, PeterVachon, CelineSlager, SusanChenevix-Trench, GeorgiaPharoah, Paul D. P.Monteiro, Alvaro A. N.García-Closas, MontserratEaston, Douglas F.Antoniou, Antonis C. et al. (Nature Publishing Group, 2016-04-27)Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10$^{−8}$) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated ... -
Identification of Novel Genetic Markers of Breast Cancer Survival
Guo, Qi; Schmidt, Marjanka K.; Kraft, Peter; Canisius, Sander; Chen, Constance; Khan, Sofia; Tyrer, JonathanBolla, Manjeet K.Wang, QinDennis, JoeMichailidou, KyriakiLush, MichaelKar, SiddharthaBeesley, JonathanDunning, Alison M.Shah, MitulCzene, KamilaDarabi, HatefEriksson, MikaelLambrechts, DietherWeltens, CarolineLeunen, KarinBojesen, Stig E.Nordestgaard, Børge G.Nielsen, Sune F.Flyger, HenrikChang-Claude, JennyRudolph, AnjaSeibold, PetraFlesch-Janys, DieterBlomqvist, CarlAittomäki, KristiinaFagerholm, RainerMuranen, Taru A.Couch, Fergus J.Olson, Janet E.Vachon, CelineAndrulis, Irene L.Knight, Julia A.Glendon, GordMulligan, Anna MarieBroeks, AnnegienHogervorst, Frans B.Haiman, Christopher A.Henderson, Brian E.Schumacher, FredrickLe Marchand, LoicHopper, John L.Tsimiklis, HelenApicella, CarmelSouthey, Melissa C.Cox, AngelaCross, Simon S.Reed, Malcolm W. R.Giles, Graham G.Milne, Roger L.McLean, CatrionaWinqvist, RobertPylkäs, KatriJukkola-Vuorinen, ArjaGrip, MerviHooning, Maartje J.Hollestelle, AntoinetteMartens, John W. M.van den Ouweland, Ans M. W.Marme, FederikSchneeweiss, AndreasYang, RongxiBurwinkel, BarbaraFigueroa, JonineChanock, Stephen J.Lissowska, JolantaSawyer, Elinor J.Tomlinson, IanKerin, Michael J.Miller, NicolaBrenner, HermannDieffenbach, Aida KarinaArndt, VolkerHolleczek, BerndMannermaa, ArtoKataja, VesaKosma, Veli-MattiHartikainen, Jaana M.Li, JingmeiBrand, Judith S.Humphreys, KeithDevilee, PeterTollenaar, Rob A. E. M.Seynaeve, CarolineRadice, PaoloPeterlongo, PaoloBonanni, BernardoMariani, PaoloFasching, Peter A.Beckmann, Matthias W.Hein, AlexanderEkici, Arif B.Chenevix-Trench, GeorgiaBalleine, RosemarykConFab InvestigatorsPhillips, Kelly-AnneBenitez, JavierZamora, M. PilarArias Perez, Jose IgnacioMenéndez, PrimitivaJakubowska, AnnaLubinski, JanJaworska-Bieniek, KatarzynaDurda, KatarzynaHamann, UteKabisch, MariaUlmer, Hans UlrichRüdiger, ThomasMargolin, SaraKristensen, VesselaNord, SiljeEvans, D. GarethAbraham, Jean E.Earl, Helena M.Hiller, LouiseDunn, Janet A.Bowden, SarahBerg, ChristineCampa, DanieleDiver, W. RyanGapstur, Susan M.Gaudet, Mia M.Hankinson, Susan E.Hoover, Robert N.Hüsing, AnikaKaaks, RudolfMachiela, Mitchell J.Willett, WalterBarrdahl, MyrtoCanzian, FedericoChin, Suet-FeungCaldas, CarlosHunter, David J.Lindstrom, SaraGarcía-Closas, MontserratHall, PerEaston, Douglas F.Eccles, Diana M.Rahman, NazneenNevanlinna, HeliPharoah, Paul D. P. et al. (Oxford Journals, 2015-04-18)Background: Survival after a diagnosis of breast cancer varies considerably between patients, and some of this variation may be because of germline genetic variation. We aimed to identify genetic markers associated with ... -
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
Southey, Melissa C.; Goldgar, David; Winqvist, Robert; Pylkäs, Katri; Couch, Fergus; Tischkowitz, Marc; Foulkes, WilliamDennis, JoeMichailidou, Kyriakivan Rensburg, Elizabeth J.Heikkinen, TuomasNevanlinna, HeliHopper, JohnDörk, ThiloClaes, KathleenReis-Filho, JorgeTeo, Zhi LingRadice, PaoloCatucci, IrenePeterlongo, PaoloTsimiklis, HelenOdefrey, Fabrice A.Dowty, James G.Schmidt, Marjanka K.Broeks, AnnegienHogervorst, Frans B.Verhoef, SennoCarpenter, JaneClarke, ChristineScott, RodneyFasching, Peter A.Haeberle, LotharEkici, Arif B.Beckmann, Matthias W.Peto, Juliandos-Santos-Silva, IsabelFletcher, OliviaJohnson, NicholaBolla, Manjeet K.Sawyer, Elinor J.Tomlinson, IanKerin, Michael J.Miller, NicolaMarme, FederikBurwinkel, BarbaraYang, RongxiGuénel, PascalTruong, ThérèseMenegaux, FlorenceSanchez, MarieBojesen, StigNielsen, Sune F.Flyger, HenrikBenitez, JavierZamora, M. PilarPerez, Jose Ignacio AriasMenéndez, PrimitivaAnton-Culver, HodaNeuhausen, SusanZiogas, ArgyriosDur, Christina ClarkeBrenner, HermannArndt, VolkerStegmaier, ChristaBrauch, HiltrudBruning, ThomasKo, Yon-DschunMuranen, Taru A.Aittomäki, KristiinaBlomqvist, CarlBogdanova, Natalia V.Antonenkova, Natalia N.Lindblom, AnnikaMargolin, SaraMannermaa, ArtoKataja, VesaKosma, Veli-MattiHartikainen, Jaana M.Spurdle, AmandakConFab InvestigatorsAustralian Ovarian Cancer Study GroupWauters, ElsSmeets, DominiekBeuselinck, BenoitFloris, GiuseppeChang-Claude, JennyRudolph, AnjaSeibold, PetraFlesch-Janys, DieterOlson, Janet E.Vachon, CelinePankratz, Vernon S.McLean, CatrionaHaiman, Christopher A.Henderson, Brian E.Schumacher, FredrickLe Marchand, LoicKristensen, VesselaAlnæs, Grethe GrenakerZheng, WeiHunter, David J.Lindstrom, SaraHankinson, Susan E.Kraft, PeterAndrulis, IreneKnight, Julia A.Glendon, GordMulligan, Anna MarieJukkola-Vuorinen, ArjaGrip, MerviKauppila, SailaDevilee, PeterTollenaar, Robert A. E. M.Seynaeve, CarolineHollestelle, AntoinetteGarcia-Closas, MontserratFigueroa, JonineChanock, Stephen J.Lissowska, JolantaCzene, KamilaDarabi, HatefEriksson, MikaelEccles, Diana M.Rafiq, SajjadTapper, William J.Gerty, Sue M.Hooning, Maartje J.Martens, John W. M.Collée, J. MargrietTilanus-Linthorst, MadeleineHall, PerLi, JingmeiBrand, Judith S.Humphreys, KeithCox, AngelaReed, Malcolm W. R.Luccarini, CraigBaynes, CarolineDunning, AlisonHamann, UteTorres, DianaUlmer, Hans UlrichRüdiger, ThomasJakubowska, AnnaLubinski, JanJaworska, KatarzynaDurda, KatarzynaSlager, SusanToland, Amanda E.Ambrosone, Christine B.Yannoukakos, DrakoulisSwerdlow, AnthonyAshworth, AlanOrr, NickJones, MichaelGonzález-Neira, AnnaPita, GuillermoAlonso, M. RosarioÁlvarez, NuriaHerrero, DanielTessier, Daniel C.Vincent, DanielBacot, FrancoisSimard, JacquesDumont, MartineSoucy, PennyEeles, RosalindMuir, KennethWiklund, FredrikGronberg, HenrikSchleutker, JohannaWeischer, MarenNordestgaard, Børge G.Travis, Ruth C.Neal, DavidDonovan, Jenny L.Hamdy, Freddie C.Khaw, Kay-TeeStanford, Janet L.Blot, William J.Thibodeau, StephenSchaid, Daniel J.Kelley, Joseph L.Maier, ChristianeKibel, Adam S.Cybulski, CezaryCannon-Albright, LisaButterbach, KatjaPark, JongKaneva, RadkaBatra, JyotsnaTeixeira, Manuel R.Kote-Jarai, ZsofiaAmin Al Olama, AliBenlloch, SaraRenner, Stefan P.Hartmann, ArndtHein, AlexanderRuebner, MatthiasLambrechts, Diethervan Nieuwenhuysen, ElsVergote, IgnaceLambretchs, SandrinaDoherty, Jennifer A.Rossing, Mary AnneNickels, StefanEilber, UrsulaWang-Gohrke, ShanOdunsi, KunleSucheston, Lara E.Friel, GraceLurie, GalinaKilleen, Jeffrey L.Wilkens, Lynne R.Goodman, Marc T.Runnebaum, IngoHillemanns, Peter A.Pelttari, Liisa M.Butzow, RalfModugno, FrancesmaryEdward, Robert P.Ness, Roberta B.Moysich, Kirsten B.du Bois, AndreasHeitz, FlorianHarter, PhilippKommoss, StefanKarlan, Beth Y.Walsh, ChristineLester, JennyJensen, AllanKjaer, Susanne KrügerHøgdall, EstridPeissel, BernardBonanni, BernardoBernard, LorisGoode, Ellen L.Fridley, Brooke L.Vierkant, Robert A.Cunningham, Julie M.Larson, Melissa C.Fogarty, Zachary C.Kalli, Kimberly R.Liang, DongLu, Karen H.Hildebrandt, Michelle A. T.Wu, XifengLevine, Douglas A.Dao, FannyBisogna, MariaBerchuck, AndrewIversen, Edwin S.Marks, Jeffrey R.Akushevich, LucyCramer, Daniel W.Shildkraut, JoellenTerry, Kathryn L.Poole, Elizabeth M.Stampfer, MeirTworoger, Shelley S.Bandera, Elisa V.Orlow, IreneOlson, Sara H.Bjorge, LineSalvesen, Helga B.van Altena, Anne M.Aben, Katja K. H.Kiemeney, Lambertus A.Massuger, Leon F. A. G.Pejovic, TanjaBean, YukieBrooks-Wilson, AngelaKelemen, Linda E.Cook, Linda S.Le, Nhu D.Górski, BohdanGronwald, JacekMenkiszak, JanuszHøgdall, Claus K.Lundvall, LeneNedergaard, LotteEngelholm, Svend AageDicks, EdTyrer, JonathanCampbell, IanMcNeish, IainPaul, JamesSiddiqui, NadeemGlasspool, RosalindWhittemore, Alice S.Rothstein, Joseph H.McGuire, ValerieSieh, WeivaCai, HuiShu, Xiao-OuTeten, Rachel T.Sutphen, RebeccaMcLaughlin, John R.Narod, Steven A.Phelan, CatherineMonteiro, AlvaroFenstermacher, DavidLin, Hui-YiPermuth-Wey, JenniferSellers, Thomas A.Chen, Y. AnnTsai, Ya-YuChen, ZhihuaGentry-Maharaj, AleksandraGayther, Simon A.Ramus, Susan J.Menon, UshaWu, Anna H.Pearce, Celeste L.Van Den Berg, DavidPike, Malcolm C.Dansonka-Mieszkowska, AgnieszkaPlisiecka-Halasa, JoannaMoes-Sosnowska, JoannaKupryjanczyk, JolantaPharoah, PaulSong, HonglinWinship, IngridChenevix-Trench, GeorgiaGiles, GrahamTavtigian, SeanEaston, DougMilne, Roger L. et al. (BMJ Publishing Group, 2016-09-05)Background The rarity of mutations in PALB2, CHEK2 and ATM make it difficult to estimate precisely associated cancer risks. Population-based family studies have provided evidence that at least some of these mutations are ...