Now showing items 1-4 of 4

    • Bioanalyzer chips can be used interchangeably for many analyses of DNA 

      Davies, Jessica; Denyer, Tom; Hadfield, James (BioTechniques, 2016)
      The Agilent 2100 Bioanalyzer (Agilent Technologies, CA, USA) enables small-scale gel electrophoretic separation of nucleic acids on a microfluidic chip. Shortage of chips and excess reagents is a common issue. This report ...
    • A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds 

      Bruna, Alejandra; Rueda, Oscar M; Greenwood, Wendy; Batra, Ankita Sati; Callari, Maurizio; Batra, Rajbir Nath; Pogrebniak, Katherine et al. (Elsevier, 2016-09-22)
      The inter- and intra-tumor heterogeneity of breast cancer needs to be adequately captured in pre-clinical models. We have created a large collection of breast cancer patient-derived tumor xenografts (PDTXs), in which the ...
    • The cost of reducing starting RNA quantity for Illumina BeadArrays: A bead-level dilution experiment. 

      Lynch, Andrew Graeme; Hadfield, James; Dunning, Mark James; Osborne, Michelle; Thorne, Natalie P; Tavare, Simon (2010-10-06)
      Abstract Background The demands of microarray expression technologies for quantities of RNA place a limit on the questions they can address. As a consequence, the RNA requirements have reduced over time as technologies ...
    • Progesterone receptor modulates estrogen receptor-α action in breast cancer 

      Mohammed, Hisham; Russell, I Alasdair; Stark, Rory; Rueda, Oscar M; Hickey, Theresa E; Tarulli, Gerard A; Serandour, Aurelien AA et al. (Nature Publishing Group, 2015-07-08)