Now showing items 21-25 of 25

    • Learning a novel technique to identify possible melanomas: are Australian general practitioners better than their U.K. colleagues? 

      Watson, Tony; Walter, Fiona M.; Wood, Annabel; Morris, Helen C.; Hall, Per; Karner, Simone; Emery, Jon D. (2009-04-30)
      Abstract Background Spectrophotometric intracutaneous analysis (SIAscopy™) is a multispectral imaging technique that is used to identify 'suspicious' (i.e. potentially malignant) pigmented skin lesions for further ...
    • Novel associations between common breast cancer susceptibility variants and risk-predicting mammographic density measures 

      Stone, Jennifer; Thompson, Deborah J; dos Santos Silva, Isabel; Scott, Christopher; Tamimi, Rulla M.; Lindstrom, Sara; Kraft, Peter et al. (American Association for Cancer Research, 2015-04-10)
      Mammographic density measures adjusted for age and body mass index (BMI) are heritable predictors of breast cancer risk but few mammographic density-associated genetic variants have been identified. Using data for 10,727 ...
    • Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression 

      Darabi, Hatef; McCue, Karen; Beesley, Jonathan; Michailidou, Kyriaki; Nord, Silje; Kar, Siddhartha; Humphreys, Keith et al. (Elsevier, 2015-06-11)
      Genome-wide association studies have identified SNPs near ZNF365 at 10q21.2 that are associated with both breast cancer risk and mammographic density. To identify the most likely causal SNPs, we fine mapped the association ...
    • Protocol for the MoleMateTM UK Trial: a randomised controlled trial of the MoleMate system in the management of pigmented skin lesions in primary care [ISRCTN 79932379] 

      Walter, Fiona M.; Morris, Helen C.; Humphrys, Elka; Hall, Per; Kinmonth, Ann Louise; Prevost, A. Toby; Wilson, Edward C. F. et al. (2010-05-11)
      Abstract Background Suspicious pigmented lesions are a common presenting problem in general practice consultations; while the majority are benign a small minority are melanomas. Differentiating melanomas from other pigmented ...
    • Volumetric Mammographic Density: Heritability and Association With Breast Cancer Susceptibility Loci 

      Brand, Judith S.; Humphreys, Keith; Thompson, Deborah J.; Li, Jingmei; Eriksson, Mikael; Czene, Kamila (Oxford University Press, 2014-09-15)
      Background: Mammographic density is a strong heritable trait, but data on its genetic component are limited to area-based and qualitative measures. We studied the heritability of volumetric mammographic density ascertained ...